Is candidemia mortality inevitable or a consequence of inadequate guideline adherence? [0.03%]
念珠菌血流感染高死亡率是不可避免的吗？或仅仅是治疗不规范所致？
Murilo Freua Sequeira,Caio Trevelin Sambo,Bianca Leal de Almeida et al.
Murilo Freua Sequeira et al.
Background: Candidemia is a severe healthcare-associated infection with persistently high mortality, particularly in critically ill patients. Beyond host severity, inadequate implementation of recommended management strat...
Restoring well-being: quality of life improvements following dolutegravir-based therapy after antiretroviral failure [0.03%]
基于多替拉韦的治疗改善了经其他抗逆转录病毒治疗失败的患者的生存质量
Liliane Lins-Kusterer,Carlos Brites,Marcus Vinícius Guimarães de Lacerda et al.
Liliane Lins-Kusterer et al.
Background: Dolutegravir-based antiretroviral therapy has improved virologic outcomes in people living with HIV; however, its effects on Health-Related Quality of Life (HRQoL), particularly among individuals with prior an...
Etiological profile of male urethritis and genital ulcer disease and antimicrobial susceptibility of Neisseria gonorrhoeae in Southeastern Brazil [0.03%]
2017年巴西东南部地区男性尿道炎和生殖器溃疡病的病因及淋球菌耐药性分析
Felipe Barufaldi,Maria Luiza Bazo,Jessica Motta Martins et al.
Felipe Barufaldi et al.
Background: Sexually Transmitted Infections (STIs) are major causes of male urethritis and genital ulcer disease, with increasing concern about antimicrobial resistance, particularly in Neisseria gonorrhoeae. This study a...
Martin P Dieterle,Stefano Malvestiti,Barbara Zieger et al.
Martin P Dieterle et al.
Hospitalization costs of patients with severe acute respiratory infections due to COVID-19 in a public teaching hospital: a micro-costing approach [0.03%]
新冠肺炎重症呼吸道感染住院患者的住院费用分析：微观成本核算方法
Ana Carolina Esteves da Silva Pereira,Luciana G Gallo,Ana Flávia de M Oliveira et al.
Ana Carolina Esteves da Silva Pereira et al.
Objective: To estimate the costs associated with the hospitalization of patients with Severe Acute Respiratory Infection (SARI) due to SARS-CoV-2 in a university hospital affiliated with the Brazilian Unified Health Syste...
Insights of bacterial community structure and occurrence of antibiotic resistance and antimicrobial compounds in an urban stream in the megacity of São Paulo, Brazil [0.03%]
巴西圣保罗都市区城市河流中细菌群落结构、抗生素抗性基因和抗菌物质的分布及关联分析
Nazareno Scaccia,Maria Tereza Pepe Razzolini,Gabrielly Lacerda de Aragão et al.
Nazareno Scaccia et al.
This study aimed to investigate the microbial community structure and the presence of Antibiotic-Resistant Bacteria (ARB), Antibiotic Resistance Genes (ARGs), and antimicrobial residues in an urban stream adjacent to an informal settlement ...
Tri-layer microbiology for LMIC Hospitals: linking syndromic panels with reflex culture and targeted sequencing for real world care - a narrative review [0.03%]
低收入和中等收入国家医院的三层微生物学：将综合征谱系与反射培养和定向测序联系起来以指导实际临床护理——叙事性综述
Tokeshwar Kumar Sahu,Jaishriram Rathored,Praful Patil
Tokeshwar Kumar Sahu
Rapid, syndromic molecular panels and high throughput sequencing have transformed the diagnostic landscape for sepsis, respiratory, gastrointestinal, and central nervous system infections, but their value in routine practice depends on how ...
Immune exhaustion in bacterial infections: mechanisms, consequences, and therapeutic implications [0.03%]
细菌感染中的免疫耗竭：机制、后果及治疗意义
Saeed Hemati,Zeinab Mohsenipour
Saeed Hemati
T-cell exhaustion, a well-characterized phenomenon, has historically been studied in the context of viral and oncological diseases. However, its relevance to chronic bacterial infections has only recently garnered attention. This review sum...
Trends and disparities in retention to antiretroviral therapy of people living with HIV from 2014 to 2022 in Brazil: a population-based study [0.03%]
巴西2014至2022年HIV感染者接受抗逆转录病毒治疗的留存趋势及不平等现象：基于人口层面的研究
Marcelo A de Freitas,Rosana E G G Pinho,Ana Roberta P Pascom et al.
Marcelo A de Freitas et al.
Introduction: Retention to antiretroviral therapy (ART) is critical for controlling HIV/AIDS and reducing mortality rates worldwide. In Brazil, although ART is widely accessible, challenges remain in retaining individuals...
Abevailton Miranda,Róger Jesus Costa,Juan P Aguilar Ticona et al.
Abevailton Miranda et al.
Background: Oropouche Virus (OROV) is an arbovirus endemic to parts of Central and South America, historically confined to the Amazon region. In 2023‒2024, a significant expansion of OROV circulation was reported in Braz...