Activation of AMPK/OPA1 pathway alleviates traumatic brain damage by regulating mitophagy [0.03%]
AMPK/OPA1信号通路激活通过调节自噬防治脑外伤损伤
Hao Wei,Jiushan Liao,Wei Gao et al.
Hao Wei et al.
Purpose: Mitophagy is an important process in brain damage, and the precise impact on a traumatic brain injury (TBI) model remains unclear. AMP-activated protein kinase (AMPK) regulates mitochondrial homeostasis and mitop...
Investigation of the protective efficacy of Caesalpinia sappan and spirulina against ethanol-induced experimental rat gastritis model [0.03%]
密豆木和螺旋藻对乙醇所致大鼠实验性胃炎的保护作用研究
İdris Oruç,Zelal Karakoç,Filiz Akduman et al.
İdris Oruç et al.
Purpose: To evaluate the protective effect of Caesalpinia sappan and spirulina against gastritis and determine changes in the expression of CD8, CD68, and major histocompatibility complex (MHC) molecules. ...
Protective effects of fisetin on ovarian ischemia-reperfusion injury in rats via modulation of the TLR4-MyD88-TRAF6 signaling pathway [0.03%]
檞皮素通过调节TLR4-MyD88-TRAF6信号途径对卵巢缺血再灌注损伤的保护作用
Qianqian Gao,Dan Zhao,Wencong He
Qianqian Gao
Purpose: To investigate the protective effects of fisetin on ovarian ischemia-reperfusion injury in rats, focusing on the modulation of the TLR4-MyD88-TRAF6 signaling pathway. ...
Hepatoprotective effect of lotus leaf against non-alcoholic fatty liver disease in rats via alteration of AMPK/SIRT1 and Nrf2/HO-1 signaling pathway [0.03%]
荷叶通过AMPK/SIRT1和Nrf2/HO-1信号通路改善非酒精性脂肪肝的作用机制研究
Qingxia Shen,Junqian Wang,Na Yao et al.
Qingxia Shen et al.
Purpose: In this study, we scrutinized the protective effect of lotus leaf (LF) against high-fat diet (HFD) induced liver injury in rats. Methods: ...
Randomized clinical trial comparing removal followed by topical imiquimod versus removal followed by topical methylprednisolone in the treatment of keloids [0.03%]
随机临床试验比较Keloid的治疗中去除后使用伊莫奎莫德与去除后使用甲基泼尼松龙的效果
Alexandre Spiandorello Ricciardi,Marcio Fernandes Chedid,Claudia Elizabeth Thompson et al.
Alexandre Spiandorello Ricciardi et al.
Purpose: Keloids are unaesthetic benign dermatosis characterized by a disorganized proliferation of collagen. Treatment of keloids constitutes a therapeutic challenge. The aim of this study was to evaluate the efficacy an...
Corynoline alleviates renal ischemia-reperfusion injury by enhancing Nrf2/HO-1 pathway [0.03%]
藤黄素通过增强Nrf2/HO-1信号途径缓解肾缺血再灌注损伤
Ming Chang,Buhe Sichen
Ming Chang
Purpose: The potential of corynoline in ameliorating oxidative stress and inflammatory responses has been extensively demonstrated across various diseases. However, its specific role in the context of renal ischemia-reper...
Frog skin as an alternative temporary dressing for diabetic foot ulcers treatment: animal model [0.03%]
用于糖尿病足溃疡治疗的替代性敷料（动物模型）——蛙皮研究
Cristina Pires Camargo,Janayna Terlera Paulino,Deborah Luisa de Sousa Santos et al.
Cristina Pires Camargo et al.
Purpose: Diabetic foot ulcers (DFUs) are chronic lesions, and despite extensive research, no standardized treatment exists yet. This study aimed to evaluate the effect of frog skin application as a temporary dressing on t...
Enemas with sucralfate and n-acetylcysteine can reduce inflammation and oxidative stress in colonic mucosa without fecal stream [0.03%]
不含粪便流的硫酸蔗糖和N-乙酰半胱氨酸灌肠可以减少结肠粘膜的炎症和氧化应激
Marcelo César Zanesco,Mateus Magami Yoshitani,Felipe Leonardo Fagundes et al.
Marcelo César Zanesco et al.
Purpose: To evaluate whether enemas containing sucralfate (SCF) alone or in combination with n-acetylcysteine (NAC) reduces inflammation and oxidative stress (OS) in the colonic mucosa without fecal stream. ...
Paulo Cesar de Castro Junior,Jenif Braga de Souza,Ruy Garcia Marques
Paulo Cesar de Castro Junior
Purpose: To evaluate an experimental model of anal fistulas in rats, analyze the primary challenges associated with this model, and identify its key advantages. ...
Hepatoprotective effect of Paederia foetida on paracetamol-induced hepatobiliary disease in rats via alteration of inflammatory and Nrf2/HO-1 pathway [0.03%]
通过改变炎症和Nrf2 / HO-1途径诱导的肝胆疾病对大鼠帕尔迪利亚 fetida的肝保护作用
Zhenzhen Feng,Jianyin Li
Zhenzhen Feng
Purpose: To scrutinize the hepatoprotective effect of Paederia foetida against paracetamol-induced hepatobiliary in rats. Methods: Rats...