Effects and mechanism of cerebroprotein hydrolysate on learning and memory ability in mice [0.03%]
脑蛋白水解物对小鼠学习记忆能力的影响及机制研究
L An,X Han,H Li et al.
L An et al.
Cerebroprotein hydrolysate is an extract from porcine brain tissue that acts on the central nervous system in various ways to protect neurons and improve memory, attention, and vigilance. This study examined the effect and mechanism of cere...
IFGFA: Identification of featured genes from genomic data using factor analysis [0.03%]
基于因子分析的基因组数据特征基因识别(IFGFA)算法研究
C H Fu,S Deng,J H Wu et al.
C H Fu et al.
In this study, a software tool (IFGFA) for identification of featured genes from gene expression data based on latent factor analysis was developed. Despite the availability of computational methods and statistical models appropriate for an...
KCNQ1 A340E impairs electrolyte homeostasis independently of the renin-angiotensin-aldosterone system in mice [0.03%]
KCNQ1 A340E独立于肾素血管紧张素醛固酮系统在小鼠中损害电解质稳态
Q Pan,Y Sang,C Sun et al.
Q Pan et al.
KCNQ1 (KvLQT1) is the pore-forming a-subunit of the potassium channel. To uncover its role in electrolyte metabolism, we investigated the effects of KCNQ1 A340E, a loss-of-function mutant, on J343 mice. Compared with the normal controls (C5...
Influence of environmental static electric field on antioxidant enzymes activities in hepatocytes of mice [0.03%]
环境静电场对小鼠肝细胞抗氧化酶活性的影响
S X Wu,Y Q Xu,G Q Di et al.
S X Wu et al.
With the increasing voltage of direct current transmission line, the intensity of the environmental static electric field has also increased. Thus, whether static electric fields cause biological injury is an important question. In this stu...
Effect of the extract from leaves of Liquidambar formosana Hance on S180 cells [0.03%]
Liquidambar formosana Hance树叶提取物对S180细胞的影响
Y T Zhong,X L Wang,Q J Xie et al.
Y T Zhong et al.
We examined the effects of the extract from leaves of Liquidambar formosana Hance on S180 cells and screened for antitumor active sites in the plant. Solvent extraction was conducted to prepare extracts from the leaves of L. formosana Hance...
Protein-protein interaction network construction for cancer using a new L1/2-penalized Net-SVM model [0.03%]
基于L1/2正则化的Net-SVM模型的癌症蛋白互作网络构建方法研究
H Chai,H H Huang,H K Jiang et al.
H Chai et al.
Identifying biomarker genes and characterizing interaction pathways with high-dimensional and low-sample size microarray data is a major challenge in computational biology. In this field, the construction of protein-protein interaction (PPI...
hBMP-7 induces the differentiation of adipose-derived mesenchymal stem cells into osteoblast-like cells [0.03%]
BMP-7诱导脂肪源间充质干细胞向成骨细胞样细胞的分化
Y Ren,C Han,J Wang et al.
Y Ren et al.
The aim of this study was to investigate the differentiation potential of adipose-derived mesenchymal stem cells (ADMSCs) into osteoblasts by human bone morphogenetic protein-7 (hBMP-7) induction. ADMSCs were isolated from the subcutaneous ...
S Lian,Y Tu,Y Wang et al.
S Lian et al.
Repetitive sequences of variable length are common in almost all eukaryotic genomes, and most of them are presumed to have important biomedical functions and can cause genomic instability. Next-generation sequencing (NGS) technologies provi...
Mechanism of juglone-induced apoptosis of MCF-7 cells by the mitochondrial pathway [0.03%]
walnut异硫氰酸盐通过线粒途径诱导MCF-7细胞凋亡的机制研究
Y B Ji,G S Xin,Z Y Qu et al.
Y B Ji et al.
This study investigated the nature and mechanism of juglone-induced apoptosis in the human breast cancer cell line MCF-7. The inhibitory effect of juglone on MCF-7 cell growth was evaluated by the dimethylthiazol tetrazolium assay. Morpholo...
Analysis of persistent changes to γ-aminobutyric acid receptor gene expression in Plutella xylostella subjected to sublethal amounts of spinosad [0.03%]
毒死蜱亚致死浓度对小菜蛾γ-氨基丁酸受体基因表达持久变化的影响分析
X-H Yin,Q-J Wu,Y-J Zhang et al.
X-H Yin et al.
A multi-generational approach was used to investigate the persistent effects of a sub-lethal dose of spinosad in Plutella xylostella. The susceptibility of various sub-populations of P. xylostella to spinosad and the effects of the insectic...