Gated container molecules [0.03%]
具有门控作用的容器分子
Liu Fang,Wang Hao,K N Houk
Liu Fang
Bin Sun,Bo Yang,Xuefei Huang
Bin Sun
GM1 is a common ganglioside pentasaccharide present on mammalian cell surface. It has been shown to play important roles in cellular communications and initiation of β-amyloid aggregation. In order to synthesize GM1, an efficient synthetic...
Chemoenzymatic synthesis of α2-3-sialylated carbohydrate epitopes [0.03%]
α2-3岩藻糖基化碳水化合物表位的 chemoenzymatic 合成
Huang Shengshu,Yu Hai,Chen Xi
Huang Shengshu
Sialic acids are common terminal carbohydrates on cell surface. Together with internal carbohydrate structures, they play important roles in many physiological and pathological processes. In order to obtain α2-3-sialylated oligosaccharides...
Pre-activation based stereoselective glycosylations: Stereochemical control by additives and solvent [0.03%]
基于预活化的立体选择性糖基化反应：立体专一性的控制通过添加剂和溶剂实现
Wasonga Gilbert,Zeng Youlin,Huang Xuefei
Wasonga Gilbert
Stereochemical control is an important issue in carbohydrate synthesis. Glycosyl donors with participating acyl protective groups on 2-O have been shown to give 1,2-trans glycosides reliably under the pre-activation based reaction condition...
Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds [0.03%]
增强CALUX和CAFLUX细胞生物测定法对类ダイオキシン化合物的定量检测响应力
Bin Zhao,David S Baston,Elaine Khan et al.
Bin Zhao et al.
Reporter genes produce a protein product in transfected cells that can be easily measured in intact or lysed cells and they have been extensively used in numerous basic and applied research applications. Over the past 10 years, reporter gen...
Two Remarkable Epimerizations Imperative for the Success of an Asymmetric Total Synthesis of (+)-Aigialospirol [0.03%]
(+)-Aigialospirol全合成中的两个关键的差向异构化反应
Ruth Figueroa,John B Feltenberger,Christle C Guevarra et al.
Ruth Figueroa et al.
Two remarkable epimerization processes were uncovered during our pursuit of an enantioselective synthesis of (+)-aigialospirol featuring a cyclic acetal tethered ring-closing metathesis. Through modeling, we were able to turn these two unex...
Nanotexture Optimization by Oxygen Plasma of Mesoporous Silica Thin Film for Enrichment of Low Molecular Weight Peptides Captured from Human Serum [0.03%]
纳米氧等离子体优化介孔二氧化硅薄膜的纳米结构以富集人类血清中的低分子量肽段
Ye Hu,Yang Peng,Louis Brousseau et al.
Ye Hu et al.
This study investigated the optimization of mesoporous silica thin films by nanotexturing using oxygen plasma versus thermal oxidation. Calcination in oxygen plasma provides superior control over pore formation with regard to the pore surfa...
Calciomics: prediction and analysis of EF-hand calcium binding proteins by protein engineering [0.03%]
钙分子学：利用蛋白质工程预测及分析EF手征钙结合蛋白
Chen Yanyi,Xue Shenghui,Zhou Yubin et al.
Chen Yanyi et al.
Ca(2+) plays a pivotal role in the physiology and biochemistry of prokaryotic and mammalian organisms. Viruses also utilize the universal Ca(2+) signal to create a specific cellular environment to achieve coexistence with the host, and to p...
Bioorthogonal Chemistry-A Covalent Strategy for the Study of Biological Systems [0.03%]
生物正交化学——一种用于生命体系研究的共价策略
Reyna K V Lim,Qing Lin
Reyna K V Lim