Dynamical and allosteric regulation of photoprotection in light harvesting complex II [0.03%]
光捕获复合体II的动态和别构调节在光保护中的作用
Hao Li,Yingjie Wang,Manping Ye et al.
Hao Li et al.
Major light-harvesting complex of photosystem II (LHCII) plays a dual role in light-harvesting and excited energy dissipation to protect photodamage from excess energy. The regulatory switch is induced by increased acidity, temperature or b...
A fully automated centrifugal microfluidic system for sample-to-answer viral nucleic acid testing [0.03%]
用于样品至检测结果病毒核酸测试的全自动离心微流控系统
Fei Tian,Chao Liu,Jinqi Deng et al.
Fei Tian et al.
The outbreak of virus-induced infectious diseases poses a global public-health challenge. Nucleic acid amplification testing (NAAT) enables early detection of pandemic viruses and plays a vital role in preventing onward transmission. Howeve...
Ultrasensitive label-free electrochemiluminescence immunosensor based on N-(4-aminobutyl)- N-ethylisoluminol-functionalized graphene composite [0.03%]
基于N-(4-氨基丁基)-N-乙基异鲁米诺修饰石墨烯复合材料的超灵敏无标记电化学发光免疫传感器
Jiangnan Shu,Wen Shen,Hua Cui
Jiangnan Shu
The electrochemiluminescence (ECL) behavior of N-(4-aminobutyl)-N-ethylisoluminol (ABEI)-functionalized graphene composite (ABEI-GC) modified on an indium tin oxide (ITO) electrode was studied. ABEI-GC exhibited excellent ECL activity. On t...
ZhiFei Cao,Ping Yang,QuanSheng Zhou
ZhiFei Cao
Lycorine is the major active component from the amaryllidaceae family plant Lycoris radiate, a represent traditional Chinese medicinal herb, and is one of the typical alkaloids with pyrrolophenanthridine nucleus core. Lycorine has drawn gre...
DaiZong Lin,WangKe Qian,Rolf Hilgenfeld et al.
DaiZong Lin et al.
An improved synthesis of rupintrivir (AG7088) was accomplished using three amino acids (l-glutamic acid, d-4-fluorophenylalanine, and l-valine) as the building blocks. The key fragment ketomethylene dipeptide isostere was constructed with t...
Synthesis, physicochemical and biological properties of oligonucleotides incorporated with amino-isonucleosides [0.03%]
含氨基异核苷的寡核苷酸的合成、理化性质和生物活性研究
Fang Wang,Yue Chen,Ye Huang et al.
Fang Wang et al.
Antisense oligonucleotides (ASONs) and siRNAs have been applied extensively for the regulation of cellular and viral gene expression, and RNAi is currently one of the most promising new approaches for anti-tumor and anti-viral therapy. In o...
Advances of multiplex and high throughput biomolecular detection technologies based on encoding microparticles [0.03%]
基于编码微粒的高通量生物分子检测技术进展
XiangWei Zhao,YuanJin Zhao,ZhongZe Gu
XiangWei Zhao
The rapid developments of genomics and proteomics have driven the demand for multiplex and high throughput analysis of large numbers of biomolecules in the fields of medical diagnostics, drug discovery, and environmental monitoring. Encodin...
Protein analysis based on molecular beacon probes and biofunctionalized nanoparticles [0.03%]
基于分子信标探针和生物功能化纳米颗粒的蛋白质分析方法研究
Hui Shi,XiaoXiao He,XiaoHai Yang et al.
Hui Shi et al.
With the completion of the human genome-sequencing project, there has been a resulting change in the focus of studies from genomics to proteomics. By utilizing the inherent advantages of molecular beacon probes and biofunctionalized nanopar...
Recent advances in proteolysis and peptide/protein separation by chromatographic strategies [0.03%]
近来液相色谱技术在蛋白质水解及肽/蛋白分离方面的进展
XiangMin Zhang,BaoHong Liu,LiHua Zhang et al.
XiangMin Zhang et al.
This review gives a broad glance on the progress of recent advances on proteolysis and peptide/protein separation by chromatographic strategies in the past ten years, covering the main research in these areas especially in China. The review...
Polymeric architectures of bismuth citrate based on dimeric building blocks [0.03%]
基于二聚体构建单元的柠檬酸铋聚合物架构
Nan Yang,Yan An,JiWen Cai et al.
Nan Yang et al.
Four bismuth complexes, (H2En)[Bi2(cit)2(H2O)4/3]·(H2O) x (1), (H2En)3[Bi2(cit)2Cl4]·(H2O) x (2), (HPy)2[Bi2(cit)2(H2O)8/5]·(H2O) x (3) and (H2En)[Bi2(cit)2](H2O) x (4) [cit = citrate4-; En = ethylenediamine; Py = pyridine] have been syn...