NIR-II thiopyrylium dyads guided photodynamic inactivation of Coronavirus [0.03%]
用于新型冠状病毒的近红外光动力失活的噻吡啶二聚体
Yunjie Xu,Changyu Yoon,Jong Seung Kim
Yunjie Xu
Yuan Xu,Zhixin Zhou,Nankai Deng et al.
Yuan Xu et al.
Emerging as cost-effective potential alternatives to natural enzymes, nanozymes have attracted increasing interest in broad fields. To exploit the in-depth potential of nanozymes, rational structural engineering and explicit catalytic mecha...
Simultaneous capture of ISG15 conjugating and deconjugating enzymes using a semi-synthetic ISG15-Dha probe [0.03%]
半合成的ISG15-Dha探针同时捕获ISG15连接酶和脱连接酶
Chuntong Li,Tian Wang,Lujun Liang et al.
Chuntong Li et al.
ISG15 is a ubiquitin-like (Ubl) protein attached to substrate proteins by ISG15 conjugating enzymes whose dysregulation is implicated in a multitude of disease processes, but the probing of these enzymes remains to be accomplished. Here, we...
Zhichao Liu,Ying Zhu,Liming Zhang et al.
Zhichao Liu et al.
Analyzing the complex structures and functions of brain is the key issue to understanding the physiological and pathological processes. Although neuronal morphology and local distribution of neurons/blood vessels in the brain have been know...
Wei-Hai Chen,Qi-Wen Chen,Qian Chen et al.
Wei-Hai Chen et al.
Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. ...
Jingjing Wei,Lianjie Xu,Wen-Hao Wu et al.
Jingjing Wei et al.
Information-rich molecules provide opportunities for evolution. Genetically engineered materials are superior in that their properties are coded within genetic sequences and could be fine-tuned. In this review, we elaborate the concept of g...
An automated nucleic acid detection platform using digital microfluidics with an optimized Cas12a system [0.03%]
一种使用数字微流控技术的自动化核酸检测平台，采用优化后的Cas12a系统
Zhen Sun,Kang-Feng Lin,Ze-Hang Zhao et al.
Zhen Sun et al.
Outbreaks of both influenza virus and the novel coronavirus SARS-CoV-2 are serious threats to human health and life. It is very important to establish a rapid, accurate test with large-scale detection potential to prevent the further spread...
Wenbin Wang,Wei Zhai,Ye Chen et al.
Wenbin Wang et al.
Cost-effective, rapid, and accurate virus detection technologies play key roles in reducing viral transmission. Prompt and accurate virus detection enables timely treatment and effective quarantine of virus carrier, and therefore effectivel...
Functional micro/nanobubbles for ultrasound medicine and visualizable guidance [0.03%]
用于超声药物和可视化导航的微/纳米气泡功能化研究进展
Chen Zhang,Yihong Li,Xinyong Ma et al.
Chen Zhang et al.
Chemically functionalized gas-filled bubbles with a versatile micro/nano-sized scale have witnessed a long history of developments and emerging applications in disease diagnosis and treatments. In combination with ultrasound and image-guida...
Nucleic Acids Analysis [0.03%]
核酸分析
Yongxi Zhao,Xiaolei Zuo,Qian Li et al.
Yongxi Zhao et al.
Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic ...