[Effects of ring finger and tryptophan-aspartic acid 2 on dendritic spines and synapse formation in cerebral cortex neurons of mice] [0.03%]
[环指蛋白和色氨酸天冬氨酸2对小鼠大脑皮层神经元突触棘及突触形成的影响]
T Sun,Y Wang,Z Fang et al.
T Sun et al.
Objective: To clarify the functional effects of differential expression of ring finger and tryptophan-aspartic acid 2 (RFWD2) on dendritic development and formation of dendritic spines in cerebral cortex neurons of mice. ...
[Anti-tumor mechanism of sesquiterpenoids from Cryptoporus volvatus based on molecular docking] [0.03%]
[Cryptoporus volvatus倍半萜类抗肿瘤机制的分子对接研究]
L Zhou,Z Zhao,F Xiong et al.
L Zhou et al.
Objective: To identify the target genes mediating anti-tumor effect of sesquiterpenoids from Cryptoporus volvatus and explore the possible mechanism using molecular docking and molecular dynamics simulation. ...
[27-P-CAUA induces apoptosis and mitochondrial autophagy in breast cancer cells by inhibiting HER2/PI3K/AKT signaling pathway] [0.03%]
[27-P-CAUA通过抑制HER2/PI3K/AKT信号通路诱导乳腺癌细胞凋亡和线粒体自噬]
C Huang,H Wang,C Wang
C Huang
Objective: To investigate the inhibitory effect of 27-P-coumayl-ursolic acid (27-P-CAUA), the active ingredient in triterpenoids from the leaves of Ilex latifolia Thunb, against breast cancer cells and explore the underly...
[TRIM21 suppresses invasion of hepatocellular carcinoma cells by promoting β-catenin ubiquitylation and degradation] [0.03%]
TRIM21通过促进β-连环蛋白泛素化降解抑制肝癌细胞侵袭转移
Z Zhang,Z Zhu,H Sheng et al.
Z Zhang et al.
Objective: To explore the role of TRIM21 in modulating the invasive phenotype of hepatocellular carcinoma (HCC) cells and its mechanism of action. Methods...
[Identification of onco-miRNAs in hepatocellular carcinoma and analysis of their regulatory network] [0.03%]
肝癌中致癌性miRNA的识别及其调控网络分析
J Ye,W Xu,T Chen
J Ye
Objective: To construct the regulatory network of survival-related onco-miRNAs and their target genes in hepatocellular carcinoma (HCC) and verify the interactions between the key miRNAs and their targets. ...
[Palmitic acid suppresses autophagy in neonatal rat cardiomyocytes via the cGAS-STING-IRF3 pathway] [0.03%]
棕榈酸通过cGAS-STING-IRF3信号通路抑制新生大鼠心肌细胞自噬
H Yu,Q Liu,Y Guo et al.
H Yu et al.
Objective: To investigate the effect of palmitic acid (PA) on autophagy in neonatal rat cardiomyocytes (NRCMs) and explore the underlying mechanism. Metho...
[Targeted killing of CD133+ lung cancer stem cells using paclitaxel-loaded PLGA-PEG nanoparticles with CD133 aptamers] [0.03%]
载有紫杉醇的CD133适配体修饰PLGA-PEG纳米粒靶向杀伤肺癌癌干细胞的研究
L Pang,X Huang,L Zhu et al.
L Pang et al.
Objective: To construct a polylactic acid-glycolic acid-polyethylene glycol (PLGA-PEG) nanocarrier (N-Pac-CD133) coupled with a CD133 nucleic acid aptamer carrying paclitaxel for eliminating lung cancer stem cells (CSCs)....
[Identification of traditional Chinese drugs containing active ingredients for treating myocardial infarction and analysis of their therapeutic mechanisms by network pharmacology and molecular docking] [0.03%]
[冠心病心肌梗死积极药物成分的中药品种识别及其作用机理网络药理学和分子对接分析]
S Zhao,K Liu,J Duan et al.
S Zhao et al.
Objective: To identify traditional Chinese drugs that contain active ingredients for treatment of myocardial infarction (MI) and explore their therapeutic mechanisms using network pharmacology and molecular docking techno...
[Bushen Huatan recipe for treatment of polycystic ovary syndrome: therapeutic mechanism based on network pharmacology and molecular docking] [0.03%]
补肾化痰方治疗多囊卵巢综合征的治则机制网络药理及分子对接研究
M Gao,Y Hong,M Cui et al.
M Gao et al.
Objective: To explore the pharmacological mechanism of Bushen Huatan (BSHT) recipe in the treatment of polycystic ovary syndrome (PCOS). Methods: ...
[Whole exome sequencing analysis of compound heterozygous variants of CDAN1 gene in a Chinese family with non-immune hydrops fetalis] [0.03%]
CDAN1基因复合杂合变异导致非免疫性胎儿水肿的全外显子组测序分析及其家系筛查
Y Wang,Q Li,X Sun et al.
Y Wang et al.
Objective: To study the clinical characteristics and genetic variants in a family with non-immune hydrops fetalis. Methods: Peripheral ...