[ANA- 12 inhibits spinal inflammation and alleviates acute and chronic pain in rats by targeted blocking of BDNF/TrkB signaling] [0.03%]
ANA-12通过靶向阻断BDNF/TrkB信号通路抑制脊髓炎症并缓解大鼠急慢性痛觉异常
J Zhao,H Yang,Z Wang et al.
J Zhao et al.
Objective: To investigate the inhibitory effect of ANA-12 that blocks brain-derived neurotrophic factor (BDNF)/ tropomyosin receptor kinase B (TrkB) signaling on inflammatory pain in rats and explore the underlying mechan...
[Performance of low-dose CT image reconstruction for detecting intracerebral hemorrhage: selection of dose, algorithms and their combinations] [0.03%]
低剂量CT颅内出血检测影像重建方法及剂量选择评估研究
S Fu,M Li,Z Bian et al.
S Fu et al.
Objective: To investigate the performance of different low-dose CT image reconstruction algorithms for detecting intracerebral hemorrhage. Methods: ...
[Profilin 2 is highly expressed in gastric cancer and promotes tumor cell proliferation and migration] [0.03%]
脯酰胺化蛋白2在胃癌中的高表达及其促进肿瘤细胞增殖和转移的作用
S Hu,L Shi
S Hu
Objective: To investigate the expression of profilin 2 (PFN2) in gastric cancer and assess its potential value as a novel prognostic indicator and a therapeutic target. ...
[Dihydromyricetin reverses Herceptin resistance by up-regulating miR-98-5p and inhibiting IGF1R/HER2 dimer formation in SKBR3 cells] [0.03%]
黄花素逆转赫赛汀耐药的机制研究及其增敏作用的研究InstanceId: portalgw_76024296 Skbr3细胞中二氢杨梅素通过上调miR-98-5p和抑制IGF1R/HER2二聚体的形成来逆转赫塞汀耐药性
M Zhang,C Guo,Y Chu et al.
M Zhang et al.
Objective: To explore the effect of dihydromyricetin on the expression of miR-98-5p and its mechanism in the development of Herceptin resistance in SKBR3 cells. ...
[Naphthalene allyl trifluoromethyl benzocyclopentanone inhibits proliferation and induces apoptosis of lung cancer A549 cells in vitro] [0.03%]
萘烯丙基三氟甲基苯并环戊酮体外抑制A549细胞增殖和诱导其凋亡的研究
X Wu,J He,P Li et al.
X Wu et al.
Objective: To investigate the molecular mechanism by which a novel naphthalene allyl trifluoromethyl benzocyclopentanone XX0335 inhibits the proliferation and induces apoptosis of lung cancer A549 cells. ...
[TIM-3 gene is highly expressed in ephithelial ovarian cancer to promote proliferation and migration of ovarian cancer cells] [0.03%]
TIM-3基因在卵巢癌组织中高表达并促进卵巢癌细胞的增殖和迁移作用
Y Huo,Y Wang,N An et al.
Y Huo et al.
Objective: To analyze the expression of immunoglobulin mucin molecule 3 (TIM-3) in epithelial ovarian cancer (EOC) and the effects of TIM-3 knockdown and overexpression on proliferation and migration of ovarian cancer cel...
[Inhibition of TAK1 aggravates airway inflammation by increasing RIPK1 activity and promoting macrophage death in a mouse model of toluene diisocyanate-induced asthma] [0.03%]
TAK1抑制通过增加RIPK1活性并促进巨噬细胞死亡而加重甲苯二异氰酸酯诱导的小鼠哮喘模型中气道炎症
S Yang,W Zhao,X Peng et al.
S Yang et al.
Objective: To explore the effect of transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) on toluene diisocyanate (TDI)-induced allergic airway inflammation in mice. ...
[Exploring the therapeutic mechanism of Longqi Fang for diabetic kidney disease based on network pharmacology and verification in rats] [0.03%]
基于网络药理学和大鼠模型验证的龙芪方治疗糖尿病肾病的作用机制探讨
L Xing,W Xing,H Guo
L Xing
Objective: To study the therapeutic mechanism of Longqi Fang (LQF) for diabetic kidney disease (DKD) based on GEO database and network pharmacology. Metho...
Weijie Zhan,Tao Yan,Jiawen Gao et al.
Weijie Zhan et al.
Objective Circular RNAs (circRNAs) are non-coding RNAs (ncRNA) circularized without a 3′ polyadenylation [poly-(A)] tail or a 5′ cap, resulting in a covalently closed loop structure. circRNAs were first discovered in RNA viruses in the 19...
[Practice of laparoscopic hepatectomy in primary care facilities in China: surgical planning, surgical techniques and postoperative management] [0.03%]
中国基层医院肝切除术的实践：手术计划、手术技术和术后管理
M Pan,C Zhang
M Pan
With the development and application of laparoscopic hepatectomy in major medical centers, domestic and foreign guidelines have summarized the indications, surgical techniques and operational procedures of the surgery. But in primary care f...