[Growth differentiation factor 11 attenuates hypoxia/reoxygenation injury in rat H9C2 cardiomyocytes in vitro by inhibiting thioredoxin-1 nitrative inactivation] [0.03%]
生长分化因子11通过抑制硫氧还蛋白1硝化失活减轻H9C2心肌细胞缺氧/复氧损伤
Jia Wei,Wei Jiang,Linying Xia et al.
Jia Wei et al.
Objectives: To verify the hypothesis that growth differentiation factor 11 (GDF11) attenuates myocardial ischemia/reperfusion (MI/R) injury and explore the underlying mechanism. ...
[Ethanol promotes oxaliplatin resistance in colorectal cancer by activating the TGF‑β/Smad/P21 signaling axis] [0.03%]
[乙醇通过激活TGF-β/Smad/P21信号轴促进奥沙利铂耐药在结直肠癌中的作用]
Bin Tan,Nuozhou Weng,Wentao Zeng et al.
Bin Tan et al.
Objectives: To investigate the effect of ethanol for promoting oxaliplatin resistance in colorectal cancer (CRC) and the underlying molecular mechanisms. ...
[Establishment of an gastric dysfunction and depression comorbidity model simulating clinical etiology in mice using a combined stress protocol] [0.03%]
基于临床病因建立小鼠胃功能障碍和抑郁共病的模型
Qingyang Huang,Wenwen Shen,Jin Hu et al.
Qingyang Huang et al.
Objectives: To establish a mouse model with the comorbidity of gastric dysfunction and depression mimicking clinical onset of the condition. Methods: ...
[Intravenous dexamethasone enhances efficacy of brachial plexus block via the costoclavicular space: a randomized, double-blind, single-center trial] [0.03%]
静脉注射地塞米松可增强锁骨costoclavicular空间臂丛神经阻滞效果的单中心随机双盲临床试验
Shuang Wang,Meishan Wu,Nan Sun et al.
Shuang Wang et al.
Objectives: To investigate the effect of intravenous 8 mg dexamethasone injection on the efficacy of ultrasound-guided brachial plexus block (BPB) with 20 mL 0.375% ropivacaine via the costoclavicular space (CCS). ...
[Myricetin inhibits proliferation and migration of bladder cancer cells by inhibiting HSP90AA1-mediated AKT phosphorylation] [0.03%]
山奈酚通过抑制HSP90AA1介导的AKT磷酸化抑制膀胱癌细胞增殖和迁移
Ruixu Sun,Yutong Li,Ling Zuo et al.
Ruixu Sun et al.
Objectives: To explore the targets and molecular mechanisms mediating the inhibitory effect of myricetin against bladder cancer. Methods: ...
[Chonggu Granules attenuate cartilage injury in knee osteoarthritis patients with liver-kidney deficiency syndrome by regulating the Nrf2 pathway] [0.03%]
补肾填精方通过调节核因子E2相关因子2途径改善膝骨关节炎肝肾亏虚症患者软骨损伤
Yuanyuan Cheng,Chuanbing Huang,Juan Zhang et al.
Yuanyuan Cheng et al.
Objectives: To explore the mechanism mediating the ameliorative effect of Chonggu Granules on cartilage injury in knee osteoarthritis (KOA). Methods: ...
[miR-143-3p alleviates neuropathic pain in mice with spared nerve injury by targeting the KRAS/RalA pathway and inhibiting astrocyte activation] [0.03%]
miR-143-3p通过靶向KRAS/RalA通路抑制星形胶质细胞活化从而缓解坐骨神经包裹法造模小鼠的神经病理性疼痛
Yixin Lin,Jinzhong Yao,Yeming Chen et al.
Yixin Lin et al.
Objectives: To investigate the therapeutic effect of microRNA (miR-143-3p) on neuropathic pain in mice and clarify its target gene and molecular mechanism. ...
[Ultrafine Xiebai powder alleviates lipopolysaccharide-induced acute lung injury in mice by suppressing ferroptosis and modulating the NF-κB/STAT3 signaling axis] [0.03%]
纳米细辛脑通过抑制铁死亡和调控NF-κB/STAT3信号轴缓解脂多糖致小鼠急性肺损伤
Jinchao Zhu,Ningning Shao,Zeyu Huang et al.
Jinchao Zhu et al.
Objectives: To investigate the protective effects of ultrafine Xiebai powder (UXP) against lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice and the underlying mechanism. ...
[KLF10 overexpression alleviates neuroinflammation and anxiety-depressive disorder in rats by downregulating the NF-κB/NLRP3 pathway] [0.03%]
KLF10过表达通过下调NF-κB/NLRP3信号通路缓解大鼠神经炎症和抑郁焦虑障碍
Anlan Liu,Weifeng Guo,Jianxiang Li et al.
Anlan Liu et al.
Objectives: To elucidate the neuroimmune regulatory mechanism of the circadian rhythm gene KLF10 as a biomarker for anxiety depressive disorder (ADD). Met...
[Multi-omics integration deciphers immune-metabolic heterogeneity in colorectal cancer: a prognostic model and therapeutic strategies targeting ANGPTL4/FABP4/RBP7] [0.03%]
多组学整合解码结直肠癌免疫代谢异质性：ANGPTL4/FABP4/RBP7靶向预后模型及治疗策略
Ning Ding,Tianshu Peng,Li Mo et al.
Ning Ding et al.
Objectives: To explore the heterogeneity of tumor immune microenvironment (TIME) in colorectal cancer (CRC) and the resultant treatment resistance and develop a prognostic model for predicting the treatment outcomes of CR...