[Spermine suppresses GBP5-mediated NLRP3 inflammasome activation in macrophages to relieve vital organ injuries in neonatal mice with enterovirus 71 infection] [0.03%]
spermine通过抑制巨噬细胞中GBP5介导的NLRP3炎性小体激活缓解肠道病毒71型感染新生小鼠重要器官损伤
Zhihua Tian,Qingqing Yang,Xin Chen et al.
Zhihua Tian et al.
Objectives: To observe the therapeutic effect of spermine in neonatal mouse models of severe hand, foot and mouth disease (HFMD) caused by enterovirus 71 (EV71) infection and explore its therapeutic mechanism in light of ...
[Role of the Nrf2/HO-1 pathway in cypermethrin-induced oxidative injury of mice hippocampal neurons] [0.03%]
[通过Nrf2/HO-1途径探讨氯氰聚酯诱导的小鼠海马神经元氧化损伤的作用]
Lihua Zhou,Xun Zhang,Yingying Yu et al.
Lihua Zhou et al.
Objectives: To explore whether the antioxidant axis Nrf2/HO-1 is involved in the regulation of hippocampus injury induced by cypermethrin and its underlying mechanism. ...
[A pan-cancer analysis of PYCR1 and its predictive value for chemotherapy and immunotherapy responses in bladder cancer] [0.03%]
[基于多癌种的PYCR1研究及其在膀胱癌化疗和免疫治疗反应中的预测价值]
Yutong Li,Xingyu Song,Ruixu Sun et al.
Yutong Li et al.
Objectives: To explore the potential of pyrroline-5-carboxylate reductase 1 (PYCR1) as a pan-cancer biomarker and investigate its expression, function, and clinical significance in bladder cancer (BLCA). ...
[Causal relationship between autoimmune diseases and aplastic anemia: A Mendelian randomization study] [0.03%]
自身免疫疾病与再生障碍性贫血间的因果关联：孟德尔随机化研究
Wenjie Li,Yaonan Hong,Rui Huang et al.
Wenjie Li et al.
Objectives: To investigate the causal associations between autoimmune diseases and aplastic anemia (AA) using Mendelian randomization analysis. Methods: ...
[Bioinformatics analysis of oxidative stress and immune infiltration in rheumatoid arthritis] [0.03%]
[类风湿关节炎氧化应激与免疫浸润的生物信息学分析]
Zhi Gao,Ao Wu,Zhongxiang Hu et al.
Zhi Gao et al.
Objectives: To explore the role of oxidative stress and immune infiltration in rheumatoid arthritis (RA). Methods: RA datasets GSE55235...
[High expression of CDKN3 promotes migration and invasion of gastric cancer cells by regulating the p53/NF-κB signaling pathway and inhibiting cell apoptosis] [0.03%]
CDKN3高表达通过调控p53/NF-κB信号通路及抑制细胞凋亡促进胃癌细胞迁移侵袭能力
Yi Zhang,Yu Shen,Zhiqiang Wan et al.
Yi Zhang et al.
Objectives: To investigate the expression of CDKN3 in gastric cancer and its impact on prognosis of gastric cancer patients. Methods: W...
[Aurora-A overexpression promotes cervical cancer cell invasion and metastasis by activating the NF-κBp65/ARPC4 signaling axis] [0.03%]
Aurora-A过表达通过激活NF-κBp65/ARPC4信号轴促进宫颈癌细胞侵袭和转移
Yaqing Yue,Zhaoxia Mu,Xibo Wang et al.
Yaqing Yue et al.
Objectives: To investigate the regulatory effects of Aurora-A in regulating proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of cervical cancer cells and the role of actin-related protein 2/...
[High expression of DTX2 promotes proliferation, invasion and epithelial-mesenchymal transition of oxaliplatin-resistant colorectal cancer cells] [0.03%]
DTX2高表达促进奥沙利铂耐药结直肠癌细胞增殖、侵袭及上皮间质转化
Zhennan Ma,Fuquan Liu,Xuefeng Zhao et al.
Zhennan Ma et al.
Objectives: To investigate the role of DTX2 in regulating biological behaviors of oxaliplatin-resistant colorectal cancer cells (CRC/OXA cells). Methods: ...
[Moslosooflavone ameliorates dextran sulfate sodium-induced colitis in mice by suppressing intestinal epithelium apoptosis via inhibiting the PI3K/AKT signaling pathway] [0.03%]
莫斯洛索夫 flavone通过抑制PI3K/AKT信号通路缓解美拉zen鼠结肠炎
Fei Chu,Xiaohua Chen,Bowen Song et al.
Fei Chu et al.
Objectives: To investigate the effect of moslosooflavone (MOS) for ameliorating dextran sulfate sodium (DSS)-induced colitis in mice and the underlying molecular mechanism. ...
[Catalpol reduces liver toxicity of triptolide in mice by inhibiting hepatocyte ferroptosis through the SLC7A11/GPX4 pathway: testing the Fuzheng Zhidu theory for detoxification] [0.03%]
丹参素通过SLC7A11/GPX4通路抑制肝细胞铁死亡从而降低雷公藤内酯醇致小鼠肝毒性的机制研究：扶正治毒理论的验证性实验研究
Linluo Zhang,Changqing Li,Lingling Huang et al.
Linluo Zhang et al.
Objectives: To investigate the protective effect of catalpol against triptolide-induced liver injury and explore its mechanism to test the Fuzheng Zhidu theory for detoxification. ...