[CHIR99021 alleviates neuroinflammation in a mouse model of Parkinson's disease by inhibiting the GSK-3β/NF-κB pathway] [0.03%]
[CHIR99021通过抑制GSK-3β/NF-κB途径缓解帕金森病小鼠模型的神经炎症]
Kelin Shi,Xiaochuan Qi,Shixiang Xu et al.
Kelin Shi et al.
Objectives: To investigate the effect of CHIR99021 for improving neuroinflammation in a mouse model of Parkinson's disease (PD) and the role of the GSK-3β/NF-κB pathway in mediating this effect. ...
[MBD1 knockdown inhibits proliferation, migration and angiogenesis of human umbilical vein endothelial cells in vitro] [0.03%]
沉默MBD1基因抑制人脐静脉内皮细胞的增殖、迁移及血管生成作用
Yutong Dan,Tingfu Zhang,Hongmei Liu et al.
Yutong Dan et al.
Objectives: To investigate the effects of methyl-CpG binding domain protein 1 (MBD1) on proliferation, migration, and angiogenesis in human umbilical vein endothelial cells (HUVECs). ...
[Rapid detection of fluconazole resistance in Candida tropicalis using MALDI-TOF mass spectrometry] [0.03%]
采用基质辅助激光解析电离飞行时间质谱技术快速检测光滑假丝酵母对氟康唑的耐药性
Jie Hou,Weilin Chen,Liang Peng et al.
Jie Hou et al.
Objectives: To evaluate the efficacy of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)-based antifungal susceptibility testing (MS-AFST) for rapid detection of fluconazole resi...
[Lonicera japonica attenuates oxidative stress and improves post-ischemic heart failure in mice via the STAT3/PGC-1α axis] [0.03%]
[日本绣线菊通过STAT3/PGC-1α轴减轻氧化应激并改善小鼠心肌梗死后的心力衰竭]
Miao Li,Guiying Yu,Jincheng Wang et al.
Miao Li et al.
Objectives: To investigate the mechanism by which freeze-dried water extract of Lonicera japonica alleviates oxidative stress and improves post-ischemic heart failure in mice. ...
[Chronic MRSA periprosthetic joint infection induces formation of mature tertiary lymphoid structures and osteolysis in mice] [0.03%]
慢性MRSA假体周围关节感染诱导小鼠成熟三级淋巴结构和骨溶解形成
Maihemuti Munila,Lisi Huang,Jiakai Li et al.
Maihemuti Munila et al.
Objectives: To investigate the histomorphological and functional characteristics of tertiary lymphoid structures (TLS) in a mouse model of chronic knee periprosthetic joint infection (PJI) with methicillin-resistant Staph...
[Tongqiao Huoxue Decoction-medicated rat cerebrospinal fluid attenuates oxygen and glucose deprivation-induced neuronal injury by suppressing fibrinogen-mediated NLRP3 inflammasome activation] [0.03%]
通窍活血汤药理脑脊液通过抑制纤维蛋白介导的NLRP3炎性小体激活减轻缺氧缺糖诱导的神经元损伤
Yan Wang,Ping Huang,Yuqin Peng et al.
Yan Wang et al.
Objectives: To examine the protective effects of cerebrospinal fluid from Tongqiao Huoxue Decoction-treated rats (TQHXD-CSF) against oxygen and glucose deprivation and reoxygenation (OGD/R)-induced injury in murine BV-2 m...
[High expression of CFL1 and phospho-CFL1 predicts poor prognosis and promotes migration of colon cancer cells in vitro] [0.03%]
CFL1及其磷酸化形式的高表达与结肠癌不良预后相关并促进体外细胞迁移能力增强
Linyu Wang,Xiaoyan Wang,Jijun Zhu et al.
Linyu Wang et al.
Objectives: To investigate the expressions of cofilin-1 (CFL1) and its phosphorylated form p-CFL1 in colon cancer, their relationship with clinicopathological features and patient prognosis, and their regulatory roles in ...
[Effect of Huayu Tongluo moxibustion combined with neural stem cell transplantation on hippocampal Drp1/Mfn proteins and mitochondrial dynamics in rats with vascular dementia] [0.03%]
化瘀通络灸结合神经干细胞移植对血管性痴呆大鼠海马Drp1/Mfn蛋白及线粒体动力学的影响
Weishuai Yin,Fei Li,Yi Cao et al.
Weishuai Yin et al.
Objectives: To investigate the mechanism by which Huayu Tongluo moxibustion (HYTLM) regulates mitochondrial dynamics of neural stem cells (NSCs) for treatment of vascular dementia (VD). ...
[Interpretable machine learning models for preoperative precision prediction of perineural invasion in cervical cancer to support treatment decision: a multicenter retrospective study] [0.03%]
[用于宫颈癌术前精准预测神经侵犯的可解释机器学习模型支持治疗决策多中心回顾性研究]
Mengxin Zhu,Xiao Liu,Shan Zhao et al.
Mengxin Zhu et al.
Objectives: To develop an interpretable machine learning model and web-based prediction tool for preoperative risk assessment of perineural invasion (PNI) in cervical cancer. ...
[Gastrodin alleviates hypobaric hypoxia-induced brain injury in rats by reducing neuronal ferroptosis via the P53/SLC7A11/GPX4 signaling axis] [0.03%]
天麻素通过P53/SLC7A11/GPX4信号轴降低神经元铁死亡来缓解高寒缺氧诱导的脑损伤
Jiping Yang,Yongzeng Gu,Zhenyi Fu et al.
Jiping Yang et al.
Objectives: To investigate the neuroprotective effect of gastrodin (GAS) against hypobaric hypoxia (HH)-induced brain injury in rats and the underlying mechanism. ...