[Overexpression of miR-593-5p inhibits migration, invasion and proliferation and promotes apoptosis of gastric cancer cells by targeting PLK1] [0.03%]
miR-593-5p过表达通过靶向PLK1抑制胃癌细胞迁移、侵袭和增殖并促进其凋亡
Baolong Dong,Jiangshan Peng,Jinru Li et al.
Baolong Dong et al.
Objectives: To explore the role of miR-593-5p targeting Polo-like kinase 1 (PLK1) in regulating biological behaviors of human gastric cancer (GC) cells. M...
[Jintiange Capsule alleviates glucocorticoid-induced osteoporosis in rats by inhibiting vascular endothelial cell senescence and promoting bone formation] [0.03%]
关节康胶囊通过抑制血管内皮细胞衰老和促进骨形成防治糖皮质激素诱导的骨质疏松症
Zihao Deng,Zhuan Wang,Senxiong Meng et al.
Zihao Deng et al.
Objectives: To investigate the role of cellular senescence in glucocorticoid-induced osteoporosis and explore the therapeutic mechanism of Jintiange (JTG) Capsule. ...
[Hollow copper sulfide nanocomposites combined with photothermal and photodynamic therapy inhibits malignant behaviors of esophageal cancer cells] [0.03%]
[中空硫化铜纳米复合材料联合光热和光动力疗法抑制食管癌细胞恶性行为]
Pingjuan Yang,Anqi Ji,Shuxin Liao et al.
Pingjuan Yang et al.
Objectives: To develop a hollow Cu9S8-based nanoparticles loaded with the photosensitizer IR780, investigate its photothermal and photodynamic (PTT-PDT) effects against esophageal cancer cells and analyze the underlying m...
[Erianin inhibits proliferation and migration of breast cancer cells in vitro by inhibiting Wnt/β-catenin signaling] [0.03%]
厄里阿宁通过抑制Wnt/β-catenain信号通路体外抑制乳腺癌细胞增殖和迁移作用研究
Dongwei Fan,Xuanhe Li,Tingjing Yao et al.
Dongwei Fan et al.
Objectives: To investigate the effect of erianin on proliferation, migration, invasion, and apoptosis of breast cancer cells and the underlying mechanisms. ...
[Ursolic acid in Huajie Xiaoliu Formula inhibits colorectal cancer cell growth by inducing cuproptosis] [0.03%]
华竭消瘤方中乌索酸通过诱导铜依赖性细胞死亡抑制结直肠癌细胞生长
Chenghuan Jin,Zongchao Hong,Xueyun Duan et al.
Chenghuan Jin et al.
Objectives: To investigate the molecular mechanism by which Huajie Xiaoliu Formula (HJF) and its active component ursolic acid inhibit colorectal cancer (CRC) cell growth. ...
[Glutamine-induced autophagy exacerbates muscle atrophy in cachectic nude mice: a multi-omics analysis] [0.03%]
谷氨酰胺诱导的自噬可加剧裸鼠恶病质肌肉萎缩：多组学分析
Ziyuan Li,Xiaoyu Su,Zhihan Tian et al.
Ziyuan Li et al.
Objectives: To clarify whether glutamine induces autophagy to promote skeletal muscle atrophy in cancer cachexia through integrated transcriptomic and metabolomic analyses. ...
[Ophiopogonin D alleviates doxorubicin-induced myocardial hypertrophy in mice by activating the β-catenin/FUNDC1/mitophagy axis] [0.03%]
茋草昔D通过激活β连环素/FUNDC1/线粒体自噬轴缓解阿霉素致小鼠心肌肥厚
Yanping Lei,Jiasheng Song,Lewu Xu et al.
Yanping Lei et al.
Objectives: To investigate whether ophiopogonin D (OD) alleviates doxorubicin (Dox)‑induced myocardial hypertrophy in mice by regulating the β‑catenin/FUNDC1/mitophagy signaling axis. ...
[Patient and family predictors of group intervention outcomes in children with attention-deficit/hyperactivity disorder: a multidimensional model analysis] [0.03%]
注意缺陷多动障碍儿童团体干预效果的预测因素：一个多维度模型分析
Xinmei Yang,Yongqi Wang,Xiaohua Mo et al.
Xinmei Yang et al.
Objectives: To explore individual and family characteristics associated with children's response to group interventions for attention-deficit/hyperactivity disorder (ADHD) based on multidimensional indicators of intervent...
[Jianpi Zishen Formula improves renal damage in mice with systemic lupus erythematosus by inhibiting p53-MDM2 signaling axis-mediated ferroptosis] [0.03%]
健脾滋肾方通过抑制p53-MDM2信号轴介导的铁死亡改善系统性红斑狼疮小鼠肾损伤
Yunfei Li,Chuanbing Huang,Lijun Pang et al.
Yunfei Li et al.
Objectives: To investigate the therapeutic mechanism of Jianpi Ziren Formula (JPZS) for ameliorating renal injury in mice with systemic lupus erythematosus (SLE). ...
[Key determinants of global burden of non-alcoholic fatty liver disease: machine learning combined with Mendelian randomization analysis based on GBD data] [0.03%]
基于GBD数据的机器学习结合孟德尔随机化分析揭示全球非酒精性脂肪肝疾病负担的关键决定因素
Hao Chen,Zhenhan Li,Mengjia Ji et al.
Hao Chen et al.
Objectives: To analyze the global trends, drivers, and health inequalities of non-alcoholic fatty liver disease (NAFLD) burden to identify key predictors of NAFLD-related mortality. ...