[Risks, mechanisms, and prevention strategies for cerebrovascular diseases in lunar astronauts under deep] [0.03%]
[深空探测任务中月球航天员的脑血管疾病风险、机制及预防策略]
Lei Tang,Qiaoling Tang,Ye Li et al.
Lei Tang et al.
As human deep space exploration enters a practical phase, ensuring astronaut health and safety has become a critical determinant of mission success. The cerebrovascular system, essential for maintaining brain function, is highly sensitive t...
A comprehensive guide to genome - wide DNA methylation research in neuropsychiatric disorders and its implications for deep - space environments [0.03%]
精神神经疾病全基因组DNA甲基化研究综述及其在深空环境中的意义
Sheng Xu,Shishi Min,Haixia Gu et al.
Sheng Xu et al.
Neuropsychiatric disorders arise from complex interactions between genetic and environmental factors. DNA methylation, a reversible and environmentally responsive epigenetic regulatory mechanism, serves as a crucial bridge linking environme...
[Effects of lunar soil simulant and Earth soil on lung injury in mice] [0.03%]
月球土壤模拟物和地球土壤对小鼠肺损伤的影响
Xiaoxiao Gong,Shiyue He,Yixiao Chen et al.
Xiaoxiao Gong et al.
Objectives: Due to prolonged exposure to cosmic radiation and meteorite impacts, lunar surface dust forms nanoscale angular particles with strong electrostatic adsorption properties. These dust particles pose potential in...
[Toxicity of lunar dust simulant exposure via the digestive system: Microbiota dysbiosis and multi-organ injury] [0.03%]
模拟月尘通过消化系统暴露的毒性：微生物群失调和多器官损伤
Yixiao Chen,Yiwei Liu,Shiyue He et al.
Yixiao Chen et al.
Objectives: As early as the Apollo 11 mission, astronauts experienced ocular, skin, and upper airway irritation after lunar dust (LD) was brought into the return cabin, drawing attention to its potential biological toxici...
[A family report on congenital fibrosis of extraocular muscles syndrome caused by TUBB3 gene mutation] [0.03%]
[由TUBB3基因突变所致先天性眼外肌纤维化家系报告]
Min Li,Xin Qi,Yunping Li et al.
Min Li et al.
Congenital fibrosis of extraocular muscles (CFEOM) syndrome is a genetically determined congenital disorder characterized by non-progressive ophthalmoplegia, restrictive ocular fixation, and ptosis. Its estimated incidence is approximately ...
[Research progress in gut microbiota and metabolism in the pathogenesis of chronic urticaria] [0.03%]
慢性荨麻疹发病机制中肠道微生态及代谢研究进展
Meiyun Jiang,Jiayi Wang,Cong Peng et al.
Meiyun Jiang et al.
Chronic urticaria (CU) is a persistent immune-mediated skin disease with an incompletely understood pathogenesis. As the largest micro-ecosystem in the human body, the gut microbiota participates in complex metabolic processes and produces ...
[Mechanisms by which the gut microbiota regulates depressive disorder via the tryptophan metabolic pathway] [0.03%]
[肠道菌群通过色氨酸代谢通路调控抑郁症的机制]
Jing DU,Jiao Li,Pule Liu et al.
Jing DU et al.
The relationship between gut microbiota and depressive disorder has become a research focus in recent years. Within the microbiota-gut-brain axis, the gut microbiota influences the onset and progression of depressive disorder primarily thro...
[Application advances of fractional flow reserve in endovascular treatment of lower-extremity arterial disease] [0.03%]
血流储备分数在下肢动脉疾病血管内治疗中应用进展
Lei Zhang,Jian Qiu,Dingxiao Liu et al.
Lei Zhang et al.
Fractional flow reserve (FFR), an established modality for functionally assessing coronary artery disease, is increasingly applied to diagnose and manage lower extremity arterial disease. By incorporating functional parameters, FFR enhances...
[Targeting chimera technology: A new tool for undruggable in breast cancer] [0.03%]
[靶向嵌合技术：乳腺癌难治靶点的新工具]
Zhongwu Chen,Sandi Shen,Xiaoyu Song et al.
Zhongwu Chen et al.
Breast cancer is one of the most common and fatal malignancies among women worldwide, and its treatment efficacy is often limited by drug resistance and the presence of undruggable targets. Traditional small-molecule drugs have difficulty e...
[Current status and influencing factors of care burden in informal caregivers of patients with pressure injuries] [0.03%]
我国压疮患者家庭照护者负担现状及影响因素分析
Chunhong Ruan,Lian Mao,Jing Lu et al.
Chunhong Ruan et al.
Objectives: With the accelerating aging of the population and the rising prevalence of chronic diseases, the number of patients with pressure injuries (PIs) has increased markedly, prolonging the period of disease-related...