Xingxing Ma,Muzi Li,La Chen et al.
Xingxing Ma et al.
Stathmin 1 (STMN1) is a microtubule-binding cytoplasmic phosphoprotein that promotes microtubule depolymerization or inhibits microtubule assembly, thereby regulating cytoskeletal organization and cell cycle progression. STMN1 is upregulate...
[Association between stigma and quality of life in community-dwelling patients with schizophrenia: Multiple mediating roles of anxiety and depression symptoms] [0.03%]
精神分裂症社区患者污名与生活质量之间的关系：焦虑和抑郁症状的多重中介作用分析
Yue Chen,Xiaoyan Wan,Qin Yang et al.
Yue Chen et al.
Objectives: Stigma is common among community-dwelling patients with schizophrenia and has a profound negative impact on both psychiatric symptoms and quality of life. This study aims to explore the association between sti...
Gender differences in the burden of near vision loss in China: An analysis based on GBD 2021 data [0.03%]
基于GBD 2021数据的中国近视力损失性别差异负担分析
Yu Liu,Liping Zhu,Yanhui Lin et al.
Yu Liu et al.
Objectives: Near vision loss (NVL) is one of the leading causes of visual impairment worldwide, exerting a profound impact on individual quality of life and socio-economic development. This study aims to analyze the burde...
[Nomogram and machine learning models for predicting in-hospital mortality in sepsis patients with deep vein thrombosis] [0.03%]
[脓毒症深静脉血栓患者的院内死亡预测 nomogram和机器学习模型]
Hongwei Duan,Huaizheng Liu,Chuanzheng Sun et al.
Hongwei Duan et al.
Objectives: Global epidemiological data indicate that 20% to 30% of intensive care unit (ICU) sepsis patients progress to deep vein thrombosis (DVT) due to coagulopathy, with an associated mortality rate of 25% to 40%. Ex...
[Establishment and application of a UPLC-MS/MS method for the determination of tiletamine and its metabolite in biological samples] [0.03%]
高效液相色谱-质谱法建立并应用于生物样本中地西泮及其代谢物的测定研究
Zihao Cai,Wenguang Yan,Jiahao Li et al.
Zihao Cai et al.
Objectives: Tiletamine, a veterinary anesthetic, has emerged as a novel psychoactive substance and has been abused in many parts of the world, causing great harm to public health. However, the sensitivity of existing dete...
[Effect of morphine pump in prepontine cistern via lumbar approach for intractable head and neck cancer pain] [0.03%]
腰穿入路桥小脑角脑脊液腔美沙酮泵治疗顽固性头颈部癌痛的效果观察
Wenjie Zhang,Bohua Yin,Xinning Li et al.
Wenjie Zhang et al.
Objectives: Managing patients with refractory head and neck cancer pain is one of the more challenging issues in clinical practice, and traditional intrathecal drug delivery also fails to provide adequate analgesia. There...
[Ameliorative effects and mechanisms of an integrated endoplasmic reticulum stress inhibitor on lipopolysaccharide-induced cognitive impairment in mice] [0.03%]
内质网应激整合抑制剂改善脂多糖致小鼠认知障碍及机制研究
Dandan Liu,Wenjia Liu,Lihua Xie et al.
Dandan Liu et al.
Objectives: The integrated endoplasmic reticulum stress inhibitor (ISRIB) is a selective inhibitor of the protein kinase R-like endoplasmic reticulum kinase (PERK) signaling pathway within endoplasmic reticulum stress (ER...
[Itaconic acid alleviates macrophage PANoptosis in sepsis - associated acute lung injury via inhibiting ninjurin - 1 - mediated plasma membrane rupture] [0.03%]
柠檬酸通过抑制NINJ1介导的细胞膜破裂缓解脓毒症相关急性肺损伤中的巨噬细胞PANoptosis
Mengrui Chen,Xiaohua Tan,Wenjing Zhong et al.
Mengrui Chen et al.
Objectives: Sepsis-associated acute lung injury (S-ALI) is one of the major causes of death in intensive care unit (ICU) patients, yet its mechanisms remain incompletely understood and effective therapies are lacking. Lyt...
Effect of retinoic acid on delayed encephalopathy after acute carbon monoxide poisoning: Role of the lncRNA SNHG15/ LINGO-1/BDNF/TrkB axis [0.03%]
全反式维甲酸通过介导长链非编码RNA SNHG15/LINGO-1信号通路改善一氧化碳中毒迟发性脑病患者的疗效
Fangling Huang,Su&#x;e Wang,Zhengrong Peng et al.
Fangling Huang et al.
Objectives: The neurotoxicity of carbon monoxide (CO) to the central nervous system is a key pathogenesis of delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). Our previous study found that retinoic ac...
[ANXA2 and NF - κB positive feedback loop promotes high glucose - induced pyroptosis in renal tubular epithelial cells] [0.03%]
[ANXA2和NF-κB正反馈循环促进高糖诱导的肾小管上皮细胞焦亡]
Jiayi Yang,Yang Luo,Zixuan Zhu et al.
Jiayi Yang et al.
Objectives: Pyroptosis plays a critical role in tubulointerstitial lesions of diabetic kidney disease (DKD). Annexin A2 (ANXA2) is involved in cell proliferation, apoptosis, and adhesion and may be closely related to DKD,...