[Predictors of short-term antimicrobial treatment outcomes in patients with liver failure complicated by spontaneous bacterial peritonitis: A retrospective study] [0.03%]
肝硬化合并自发性细菌性腹膜炎短期抗感染治疗结局的影响因素分析：回顾性研究
Yangmei Zhou,Duoduo Li,Limin Chen et al.
Yangmei Zhou et al.
Objectives: Spontaneous bacterial peritonitis (SBP) is a common complication of liver failure and is associated with high mortality. This study aims to identify factors associated with the effectiveness of antimicrobial t...
Multi-omics investigation into the role of PTK7 as a driver of liver fibrosis [0.03%]
PTK7在肝纤维化中的驱动作用的多组学研究
Yongwen Yang,Jun Chen,Zebing Huang
Yongwen Yang
Objectives: Liver fibrosis is a critical stage in the progression of chronic liver disease to cirrhosis, and effective antifibrotic targets remain lacking. This study aims to investigate the association between protein ty...
[Untargeted metabolomics-based exploration of potential metabolic biomarkers for subclinical atherosclerosis in metabolic-associated fatty liver disease] [0.03%]
基于非靶向代谢组学探索代谢相关性脂肪肝病亚临床动脉粥样硬化的潜在代谢标志物
Yaqin Wang,Ting Yuan,Lei Liu et al.
Yaqin Wang et al.
Objectives: Cardiovascular disease is the most common extrahepatic complication and leading cause of death in metabolic dysfunction‑associated fatty liver disease (MAFLD). However, early metabolic biomarkers for subclini...
[A prediction model for early neurological improvement after intravenous thrombolysis in patients with acute ischemic stroke] [0.03%]
[急性缺血性卒中患者静脉溶栓后早期神经功能改善的预测模型]
Dujie Xie,Panyao Long,Shuntong Hu et al.
Dujie Xie et al.
Objectives: Early neurological improvement (ENI) is an important prognostic indicator in patients with acute ischemic stroke (AIS) receiving intravenous thrombolytic therapy. This study aims to develop and validate a mach...
[Chrysophanol alleviates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and inhibiting M1 macrophage polarization] [0.03%]
大黄素通过维持线粒体稳态和抑制M1型巨噬细胞极化治疗脓毒症相关急性肾损伤
Wei Zhang,Lele Wang,Ruihan Ge et al.
Wei Zhang et al.
Objectives: Sepsis-associated acute kidney injury (SA-AKI) is a major cause of mortality in critically ill patients. Imbalanced macrophage polarization plays a crucial role in the progression of SA-AKI, in which classical...
[miR-16-5p alleviates airway inflammation in asthmatic rats by regulating TXNIP and suppressing the NLRP3 signaling axis] [0.03%]
miR-16-5p通过调控TXNIP和抑制NLRP3信号轴来缓解哮喘大鼠气道炎症
Weiwei She,Mingde She,Tianshou Sun et al.
Weiwei She et al.
Objectives: Asthma is a chronic inflammatory airway disease. Thioredoxin-interacting protein (TXNIP), a thioredoxin (TRX)-binding protein, is involved in the regulation of inflammatory responses and apoptosis. The NOD-lik...
[Mechanisms of gut - derived trimethylamine - N - oxide in mediating multiple organ injury in post - cardiac arrest syndrome] [0.03%]
[肠道产生的三甲胺-N-氧化物介导心脏停搏后综合征多器官损伤的机制]
Xuanyi Gong,Shi Chen,Ting Zhang et al.
Xuanyi Gong et al.
Post-cardiac arrest syndrome (PCAS) is characterized by systemic ischemia-reperfusion injury as its central pathological basis and is associated with severe multiple organ dysfunction. In recent years, increasing attention has been directed...
[Advances in the application of the HEART score in patients with acute coronary syndromes] [0.03%]
[高危急性冠脉综合征患者HEART评分临床应用进展]
Hongyu Zhao,Caiyun Tang,Yinglong Duan et al.
Hongyu Zhao et al.
Acute coronary syndromes (ACS) are among the most critical cardiovascular emergencies in clinical practice. Rapid identification, accurate risk stratification, and early intervention are essential for improving patient outcomes. The HEART s...
[Research progress on the metabolic regulatory mechanisms of coronary collateral circulation] [0.03%]
冠状动脉侧支循环代谢调节机制研究进展
Lingping Zhu,Yongping Bai
Lingping Zhu
Coronary collateral circulation (CCC) develops in response to coronary artery stenosis or occlusion and helps maintain myocardial perfusion and attenuate ischemic injury. Shear stress and signaling pathways play crucial roles in collateral ...
[Analysis of cardiovascular adverse events associated with 8 immune checkpoint inhibitors based on the FAERS database] [0.03%]
基于FAERS数据库的8种免疫检查点抑制剂心血管不良事件分析
Linlu Huang,Caihong Qu,Wei Dai et al.
Linlu Huang et al.
Objectives: Immune checkpoint inhibitors (ICIs) are increasingly used in cancer therapy; however, systematic epidemiological studies of ICI-associated cardiovascular adverse events in China remain limited. This study aims...