LncRNA AK154753 mediates the development of acute kidney ischemia reperfusion injury via the miR - 345 - 3p/Bak and miR - 708 - 5p/Bim pathways [0.03%]
长链非编码RNA AK154753通过miR-345-3p/Bak和miR-708-5p/Bim途径介导急性肾脏缺血再灌注损伤的发展
Yanlin Wen,Yi He,Yunzhen Deng et al.
Yanlin Wen et al.
Objectives: Acute kidney injury (AKI) is a clinical syndrome characterized by sudden deterioration of renal function, with ischemia reperfusion injury (IRI) being the most common cause. Long noncoding RNA (lncRNA) regulat...
[Heterogeneity in the regulation of cellular stress responses by FUS gene mutations associated with amyotrophic lateral sclerosis] [0.03%]
与肌萎缩侧索硬化相关的FUS基因突变调节细胞应激反应的异质性
Chenchen Yu,Weiqian Zeng,Piyanat Meekrathok et al.
Chenchen Yu et al.
Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective death of motor neurons, exhibiting marked clinical heterogeneity and lacking effective treatment. T...
Mechanisms of gypenosides in type 2 diabetes mellitus via regulation of m6A methylase METTL3/14 and demethylase FTO [0.03%]
甘草苷通过调节m6A甲基转移酶METTL3/14和去甲基酶FTO改善2型糖尿病的机制研究
Jiayi Li,Shaoqian Zhang,Renwei Tian et al.
Jiayi Li et al.
Objectives: Type 2 diabetes mellitus (T2DM) is characterized by insufficient insulin secretion and insulin resistance. Gypenosides (GPs) are the major bioactive saponins extracted from Gynostemma pentaphyllum. Previous st...
[Progress in the application of artificial intelligence in assisted reproduction] [0.03%]
人工智能辅助生殖应用进展
Qiuyao Li,Ting Wang,Yidan Liu et al.
Qiuyao Li et al.
As a disease that seriously affects the health of men and women of childbearing age, the incidence of infertility is increasing worldwide, and the popularization of assisted reproductive technology (ART) is expected to improve the situation...
[Application of large language models in health education for patients with pediatric cataract] [0.03%]
[大型语言模型在儿童白内障患者健康教育中的应用]
Yuyu Guo,Yue Zhang,Yanhui Xu et al.
Yuyu Guo et al.
Objectives: Pediatric cataract occurs during the critical period of visual development, and early intervention is essential to avoid irreversible visual impairment. The health literacy and self-management ability of child...
[Interpretable machine learning-based predictive model for assessing abdominal surgery risk and biologic therapy efficacy in CDAI 0 to 1 level Crohn disease patients] [0.03%]
[基于解释性机器学习的预测模型在CDAI0至1级克罗恩病患者腹腔手术风险及生物制剂疗效评估中的应用]
Kailing Xie,Qi Sun,Zhixian Jiang et al.
Kailing Xie et al.
Objectives: Crohn disease (CD) patients face a clinically significant high risk of abdominal surgery. This study aims to develop a predictive model for estimating abdominal surgery in CD patients with Crohn Disease Activi...
[A multi-molecular predictive model for lymph node metastasis in papillary thyroid carcinoma based on machine learning algorithms] [0.03%]
基于机器学习算法的乳头状甲状腺癌淋巴结转移多分子预测模型
Zhijun Zhan,Lu Chen,Yan Sun et al.
Zhijun Zhan et al.
Objectives: Accurate preoperative evaluation of lymph node metastasis (LNM) status in patients with papillary thyroid carcinoma (PTC) is essential for the development of individualized diagnosis and treatment strategies; ...
[Etiological evaluation of pericardial effusion : A case report of adult ECD - LCH overlap syndrome] [0.03%]
成人ECD-LCH重叠综合征心包积液病因分析1例报告
Leng Huang,Ling Qin
Leng Huang
Langerhans cell histiocytosis (LCH) is a group of myeloid neoplastic disorders characterized by infiltration of Langerhans cells, which can accumulate in tissues and cause multisystem manifestations. Erdheim-Chester disease (ECD) is a rare ...
Yi Tang,Laiquan Zou,Xuanxuan Chen et al.
Yi Tang et al.
Depressive disorder is a highly prevalent psychiatric condition that imposes substantial psychological burden on patients and their families, as well as significant economic costs to society. A close relationship exists between depressive d...
[Biological activities of Polygonatum polysaccharides and their roles in the prevention and treatment of related diseases] [0.03%]
Polygonatum属多糖的生物活性及其在相关疾病预防和治疗中的作用研究进展
Peiyao Guan,Ziye Li,Qian Wang et al.
Peiyao Guan et al.
Polygonatum polysaccharides are the major active components of the traditional Chinese medicinal herb Polygonatum. They exhibit marked structural heterogeneity with diverse glycan types and possess a broad spectrum of biological activities,...