[Potential of early diagnosis and targeted therapy for Klotho protein in chronic kidney disease] [0.03%]
[在慢性肾脏病中早期诊断和靶向治疗克洛托蛋白的潜力]
Yifeng Li,Guihong Chen,Meijun Chen et al.
Yifeng Li et al.
Klotho (KL) protein is a key renoprotective protein that exerts organ-protective effects through regulation of mineral metabolism, anti-inflammatory and antioxidant activity, anti-aging signaling, modulation of autophagy, and inhibition of ...
[Mechanistic research progress on radiotherapy resistance of cancer stem cells] [0.03%]
癌症干细胞放射抵抗机制研究进展
Zhiwei Luo,Mingkai Yu,Jingyi Li et al.
Zhiwei Luo et al.
Radiotherapy is an important treatment modality for tumors and is involved in the treatment course of more than 50% of cancer patients. However, resistance to ionizing radiation results in suboptimal radiotherapy efficacy and contributes to...
[Role and mechanisms of FoxO3a-related signaling pathways in breast cancer cell apoptosis] [0.03%]
FoxO3a相关信号通路在乳腺癌细胞凋亡中的作用及机制
Zhongxu Wang,Haoming Tang,Xiaotong Shao et al.
Zhongxu Wang et al.
Breast cancer is one of the most common malignant tumors in women worldwide, and its high incidence and mortality rate seriously threaten women's health. Studies show that the forkhead box O3a (FoxO3a) plays a key role in the occurrence and...
Qi Jia,Kangmei Shao,Yangrun Li et al.
Qi Jia et al.
Aiolos is a member of the Ikaros zinc-finger protein family and is encoded by the Ikaros family zinc finger 3 (IKZF3) gene. Aiolos not only plays a crucial role in controlling the normal differentiation and proliferation of lymphocytes, but...
[Value of small bowel stenosis in Crohn ' s disease using small intestinal contrast ultrasound and evaluation of double - balloon endoscopy entry pathway] [0.03%]
克罗恩病小肠狭窄的肠系膜超声评价及双气囊小肠镜入口路径评估价值分析
Ying Mei,Yuanyuan Yang,Xuemei Li et al.
Ying Mei et al.
Objectives: Small bowel stenosis constitutes a frequent complication of Crohn's disease (CD). Early diagnosis of small bowel stenosis can guide individualized treatment, help avoid intestinal obstruction, and improve prog...
[Retinal protective effects of zinc - loaded magnesium oxide nanoparticles in a glutamate - excitotoxicity glaucoma model] [0.03%]
锌掺杂氧化镁纳米颗粒在谷氨酸兴奋毒性青光眼模型中的视网膜保护作用研究
Lemeng Feng,Yisong Chen,Chao Wang et al.
Lemeng Feng et al.
Objectives: Glaucoma is pathologically characterized by the progressive loss of retinal ganglion cells (RGCs). Currently, effective strategies for protection of RGCs in glaucoma remain lacking, and nanomaterials represent...
[CT radiomics - driven lung cancer subtyping based on pretreatment imaging: A single - center retrospective cohort study] [0.03%]
基于治疗前影像的肺癌分型的ct影像组学方法：单中心回顾性队列研究
Fuchang Han,Jinfan Zhang,Xueying Wang et al.
Fuchang Han et al.
Objectives: Platinum-based chemotherapy for advanced lung cancer is frequently challenged by platinum resistance, and effective early identification methods remain lacking. Although previous studies have demonstrated the ...
Exploration of safety indicators for radiotherapy in hepatocellular carcinoma: A real-world study [0.03%]
基于真实世界研究的肝细胞癌放射治疗安全性指标探索分析
Xueyi Xie,Xi Zhang,Honghua Peng et al.
Xueyi Xie et al.
Objectives: Hepatocellular carcinoma (HCC) is the most common pathological subtype of primary liver cancer and is associated with high incidence and mortality. External beam radiation therapy (EBRT) is a widely used local...
[Nitrosative stress promotes the malignant biological behavior of breast cancer through the glycolytic pathway] [0.03%]
硝应激通过促进糖酵解途径而促进乳腺癌恶性生物学行为
Yalu Wang,Mingyan Gong,Yunhao Zhu et al.
Yalu Wang et al.
Objectives: Breast cancer is one of the most common malignant tumors in women, and some patients face poor therapeutic efficacy and recurrence. Tumor cells are extremely dependent on the energy produced by the glycolytic ...
[Correlation between JAG1 ligand gene polymorphisms in the Notch signaling pathway and preeclampsia] [0.03%]
notch信号通路JAG1配体基因多态性与子痫前期的相关性分析
Fan Xia,Changxiang Ye,Yurong Jiang et al.
Fan Xia et al.
Objectives: Preeclampsia (PE) is a clinical syndrome characterized by new-onset hypertension and proteinuria after 20 weeks of gestation, seriously affecting the short- and long-term health of both mothers and infants. Th...