Toxic epidermal necrolysis associated with immune checkpoint inhibitors for bladder cancer: A case report [0.03%]
免疫检查点抑制剂治疗膀胱癌相关中毒性表皮坏死松解症1例报告
Yangyang Wang,Lihua Liu,Meiyun Li
Yangyang Wang
Immune checkpoint inhibitors (ICIs) play a significant role in tumor treatment, but the immune-related adverse events (irAEs), which brings about have also attracted much attention. Among them, toxic epidermal necrolysis (TEN) is one of the...
[Role of m6A methylation modification in photoaging and ultraviolet-induced skin cancers] [0.03%]
m6A甲基化修饰在光老化及紫外线诱导皮肤癌变中的作用
Yanni Hou,Xiaoqing Zhang,Jun Liu et al.
Yanni Hou et al.
Ultraviolet (UV) radiation, one of the critical environmental carcinogenic factors, promotes skin photoaging and carcinogenesis by inducing DNA damage, oxidative stress, and chronic inflammatory cascades. N6-methyladenosine (m6A)-modifying ...
[Patterns and mechanisms of the " treating skin with skin " therapy under traditional Chinese medicine analogical thinking based on data mining and network pharmacology] [0.03%]
基于数据挖掘和网络药理学的中医类比思维下“以皮治皮”疗法的应用规律与机制探讨
Xiaoli Hu,Hui Guo,Guoyan Sun et al.
Xiaoli Hu et al.
Objectives: Under the guidance of analogical thinking in traditional Chinese medicine (TCM), the "treating of skin with skin" therapy, using processed animal and plant skin-derived medicinal materials to treat skin diseas...
[Data mining and toxicity profile analysis of immune checkpoint inhibitor-related skin toxicity events based on FAERS] [0.03%]
基于FAERS的免疫检查点抑制剂相关皮肤毒副反应的数据挖掘及毒性特征分析
Siyao Ma,Mingzhu Li,Yanyi Ren et al.
Siyao Ma et al.
Objectives: The widespread use of immune checkpoint inhibitors (ICIs) has led to breakthrough advances for patients with various advanced solid tumors. As the skin is an important target organ of immune responses, it is t...
[A multimodal disease-specific cohort for melanoma research: Construction, governance, and preliminary report] [0.03%]
[一种多模态黑色素瘤疾病特异性队列的构建、管理及初步结果报告]
Dongcheng Xie,Yongxiang Yuan,Shuang Zhao et al.
Dongcheng Xie et al.
Objectives: Given the high incidence, poor prognosis, and scarcity of high-quality multimodal research data for acral melanoma in the Chinese population, this study aims to build a representative multimodal disease-specif...
[Machine learning-based programmed cell death signature model for precise prediction of prognosis and treatment response in melanoma] [0.03%]
基于机器学习的细胞程序性死亡谱型模型在黑色素瘤预后及治疗反应精准预测中的应用研究
Benliang Wei,Hong Liu
Benliang Wei
Objectives: The occurrence, metastasis, and drug resistance of melanoma pose major challenges to patient prognosis, and predictive models capable of accurately forecasting patient outcomes and guiding treatment are still ...
[Glomerulopathy with fibronectin deposits caused by FN1 gene mutation: A familial case report and literature review] [0.03%]
FN1基因突变所致系膜增生性肾小球肾炎伴冷球蛋白血症及免疫复合物沉积一家系病例报告及文献复习
Qianting Chen,Li Qin,Yumei Luo et al.
Qianting Chen et al.
Glomerulopathy with fibronectin deposits (GFND) is a rare familial aggregation of autosomal dominant nephropathy. Proteinuria, hematuria, hypertension and progressive deterioration of renal function are the main clinical manifestations, whi...
[Antibacterial properties, biocompatibility, and clinical selection strategies of root canal filling materials for primary teeth] [0.03%]
乳牙根管填充材料的抗菌性能、生物相容性及其临床选择策略
Hongfeng Wang,Ousheng Liu,Piao Li et al.
Hongfeng Wang et al.
Root canal treatment for primary teeth is a critical therapy aimed at eliminating infected tissue, relieving pain, and preserving the primary tooth until its natural exfoliation and replacement. The success of this treatment largely depends...
Tong Wu,Xiya Wen,Jiaxin Zhang et al.
Tong Wu et al.
Tear fluid, also referred to as tears or tear film, is an important biological fluid that plays a key role in maintaining ocular surface health and immune homeostasis. Recent studies have found that tear fluid not only participates in the o...
[Application of flavonoid in disease treatment based on multi-omics technologies] [0.03%]
基于组学技术的黄酮类化合物疾病治疗应用研究进展
Weihua Zhang,Kezhen Han,Kexin Zhao et al.
Weihua Zhang et al.
Flavonoids are naturally occurring polyphenolic compounds widely distributed in nature, exhibiting pharmacological activities including anti-inflammatory effects and inhibition of cell proliferation. Their broader application has been const...