Astrocytes promote oligodendrocyte precursor cell proliferation via Cx47 - mediated regulation of exosome - derived CHI3L1 secretion [0.03%]
星形胶质细胞通过Cx47介导调节CHI3L1外泌体分泌促进少突胶质前体细胞增殖
Xiaoyan Zhang,Nannan Cheng,Yan Peng
Xiaoyan Zhang
Objectives: Neurodegenerative diseases are closely associated with myelin loss, and the proliferation and differentiation of oligodendrocyte precursor cells (OPCs) are crucial to remyelination. However, the regulatory mec...
Wanyun Ma,Liang Zhao,Wen Zhou
Wanyun Ma
Multiple myeloma (MM) is a common hematologic malignancy that originates from precursor conditions such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). Identifying its risk factors is cruc...
Clinical significance of CD45 and CD200 expression in newly diagnosed multiple myeloma patients [0.03%]
CD45和CD200在新诊断多发性骨髓瘤患者中的临床意义
Xinyi Long,Jing Liu,Rong Hu et al.
Xinyi Long et al.
Objectives: Multiple myeloma (MM) is a hematologically malignant clonal plasma cell disease. This study aims to explore the association between immunophenotypes and prognosis in patients with MM, to determine whether the ...
Construction of a treatment response prediction model for multiple myeloma based on multi-omics and machine learning [0.03%]
基于多组学和机器学习的弥漫大B细胞淋巴瘤治疗反应预测模型构建
Xionghui Zhou,Rong Gui,Jing Liu et al.
Xionghui Zhou et al.
Objectives: Multiple myeloma (MM) is a hematologic malignancy characterized by clonal proliferation of plasma cells and remains incurable. Patients with primary refractory multiple myeloma (PRMM) show poor response to ini...
A prognostic model for multiple myeloma based on lipid metabolism related genes [0.03%]
基于脂质代谢相关基因的多发性骨髓瘤预后模型
Zhengjiang Li,Liang Zhao,Fangming Shi et al.
Zhengjiang Li et al.
Objectives: Multiple myeloma (MM) is a highly heterogeneous hematologic malignancy, with disease progression driven by cytogenetic abnormalities and a complex bone marrow microenvironment. This study aims to construct a p...
A case of mitochondrial encephalomyopathy remarkable presenting with refractory shock [0.03%]
一例线粒体脑肌病伴难治性休克的病例报告
Yang Liao,Daomiao Xu,Li Li
Yang Liao
Mitochondrial encephalomyopathy is a multisystemic metabolic disorder caused by mutations in mitochondrial or nuclear genes. It commonly presents with stroke-like episodes or myopathy as initial symptoms. This paper reports a young male pat...
Yuchun Yang,Xiaojie Zhang,Ti Chen
Yuchun Yang
In recent years, gut microbiota has been increasingly recognized as a key player in ethanol metabolism and the development of related diseases. On one hand, ethanol intake directly affects the gut, leading to significant alterations in micr...
Characteristics of the amygdala and its subregions in premenstrual syndrome/premenstrual dysphoric disorder patients [0.03%]
前月经期综合征/经前心境不良障碍患者杏仁核及其亚区的特征研究
Ming Cheng,Baoyi Li,Zhen Zhang et al.
Ming Cheng et al.
Premenstrual dysphoric disorder (PMDD) is considered a severe form of premenstrual syndrome (PMS). As a key brain region involved in emotional regulation and stress responses, the amygdala has been implicated in the pathogenesis of PMS/PMDD...
Effect of different surgical approaches for intrauterine adhesions patients on pregnancy outcomes [0.03%]
不同手术入路治疗宫腔粘连患者的妊娠结局分析
Ping Guo,Meiqin Chen,Shan Liu et al.
Ping Guo et al.
Objectives: Transcervical resection of adhesions (TCRA) under hysteroscopy is the mainstay treatment for intrauterine adhesions (IUA), but its effectiveness varies depending on the surgical approach. This study aims to in...
Causal relationship between gut microbiota and diabetes based on Mendelian randomization [0.03%]
基于孟德尔随机化技术的肠道菌群与糖尿病因果关系研究
Manjun Luo,Ziye Li,Mengting Sun et al.
Manjun Luo et al.
Objectives: The gut microbiota plays a crucial role in the pathophysiology of various types of diabetes. However, the causal relationship between them has yet to be systematically elucidated. This study aims to explore th...