Distribution characteristics and influencing factors of overweight and obesity among urban and rural primary and secondary school students in Hunan Province [0.03%]
湖南省城乡中小学生超重肥胖流行特征及影响因素分布
Lixi Qin,Miyang Luo,Kexin Li et al.
Lixi Qin et al.
Objectives: The prevalence of overweight and obesity among children and adolescents continues to rise, becoming one of the most serious global public health issues of the 21st century. Given the differing growth and devel...
Analysis and projection of the disease burden of nasopharyngeal carcinoma in China based on the GBD database [0.03%]
基于GBD数据库的中国鼻咽癌疾病负担分析及预测
Yexun Song,Xiajing Liu,Yongquan Zhang et al.
Yexun Song et al.
Objectives: Nasopharyngeal carcinoma is often diagnosed at a late stage due to its concealed location and exhibits marked regional clustering, posing a significant public health challenge in China. This study aims to anal...
Effects of ultrasonic rapid processing method on the protein, DNA, and RNA in paraffin-embedded tissues [0.03%]
超声快速处理法对石蜡包埋组织中蛋白质、DNA和RNA的影响
Xiaohong Li,Jiadi Luo,Qingchun Liang et al.
Xiaohong Li et al.
Objectives: The traditional processing method for paraffin-embedded tissues is time-consuming, while the ultrasonic rapid processing method has a short processing time. However, its effects on tissue proteins, DNA, and RN...
Deep learning algorithm for pathological grading of renal cell carcinoma based on multi-phase enhanced CT [0.03%]
基于多时相增强CT的肾细胞癌病理分级深度学习算法
Haozhong Chen,Jun Liu,Kai Deng et al.
Haozhong Chen et al.
Objectives: Renal cell carcinoma (RCC) is a malignant renal tumor that poses a significant threat to patient health. Accurate preoperative pathological grading plays a crucial role in determining the appropriate treatment...
Wen Zeng,Shanhu Yao,Ying Li et al.
Wen Zeng et al.
Objectives: Metabolic syndrome (MetS) is a major public health concern that poses a significant threat to human health. Investigating its underlying mechanisms and identifying potential intervention targets has important ...
Li Qi Huo Xue Di Wan alleviates hypoxia-induced injury in human cardiac microvascular endothelial cells by inhibiting apoptosis and necroptosis pathways [0.03%]
Liqihuodidiwan通过抑制凋亡和坏死途径缓解缺氧诱导的心肌微血管内皮细胞损伤
Can Tang,Yiyue Zhang,Xiuju Luo et al.
Can Tang et al.
Objectives: Injury to human cardiac microvascular endothelial cells (HCMECs) compromises myocardial microcirculation and may contribute to major cardiovascular events such as coronary heart disease, posing a serious healt...
Role and mechanisms of interneurons in chronic pain and pain-induced cognitive impairment [0.03%]
中间神经元在慢性疼痛及疼痛诱导的认知障碍中的作用和机制研究
Qi Wang,Guangfen Zhang,Bo Wang
Qi Wang
Chronic pain, a prevalent chronic disease, frequently manifests not only in physical symptoms but also in cognitive impairment, which seriously affects patients' quality of life. Interneurons are multipolar neurons, most of which are inhibi...
BTVT ameliorates offspring blood - brain barrier damage induced by prenatal and lactational neodymium oxide exposure via the gut - brain axis [0.03%]
BTVT通过肠-脑轴改善孕期和哺乳期暴露于氧化钕引起的后代血脑屏障损伤
Xiaoyan DU,Xiaocheng Gao,Jing Cao et al.
Xiaoyan DU et al.
Objectives: Exposure to rare earth elements (REEs) has been linked to various systemic diseases, but their impact on the offspring blood-brain barrier (BBB) via the gut-brain axis remains unclear. This study aims to inves...
Noggin alleviates neuropathic pain by regulating microglial polarization and remodeling iron homeostasis via a STAT3-dependent pathway [0.03%]
Noggin通过STAT3依赖性途径调节小胶质细胞极化和重塑铁稳态以缓解神经病理性疼痛
Wenjuan Zhang,Lin Yang,Ran Zhang
Wenjuan Zhang
Objectives: Pain sensitization, as a core feature of neuropathic pain (NP), is closely associated with inflammatory imbalance within the central nervous system. To investigate the effects of intrathecal injection of noggi...
EGR2 maintains neuropathic pain by promoting microglial phagocytosis [0.03%]
EGR2通过促进小胶质细胞吞噬作用维持神经病理性疼痛
Caiyun Xi,Jianxi Zhang,Zhifeng Huang et al.
Caiyun Xi et al.
Objectives: Neuropathic pain (NP) is one of the most common forms of chronic pain, yet current treatment options are limited in effectiveness. Peripheral nerve injury activates spinal microglia, altering their inflammator...