[Research advances in immunotherapy for gastric cancer with specific molecular subtypes] [0.03%]
胃癌特定分子分型免疫治疗研究进展
B Q Zhou,Y F Tang,L Liu et al.
B Q Zhou et al.
Gastric cancer is one of the most common malignant tumors. Immunotherapy has played a significant role in the neoadjuvant, conversion, and postoperative adjuvant treatment of gastric cancer. In recent years, immunotherapies such as immune c...
M Zhuo,T Han,X Y Xiao et al.
M Zhuo et al.
In recent years, biomarkers such as HER-2, PD-L1, and Claudin 18.2 (CLDN 18.2) have provided new opportunities for precision treatment. HER-2-targeted therapies have achieved substantial advancements, while immune checkpoint inhibitors have...
[Analysis of five-year outcomes and risk factors for insufficient weight loss after laparoscopic sleeve gastrectomy in obese patients] [0.03%]
肥胖患者袖状胃切除术后五年随访结果及不足体重丢失的影响因素分析
T C Li,W J Wang,J Wang et al.
T C Li et al.
Objective: To explore the five-year outcomes of obese patients after undergoing laparoscopic sleeve gastrectomy (LSG), and to identify risk factors for insufficient weight loss. Methods: A retrospective observational study was conducted. In...
[Utilizing machine learning and SHAP analysis to develop a prognostic survival prediction model for gastric cancer patients following radical gastrectomy] [0.03%]
基于SHAP分析的机器学习胃癌根治术后预后预测模型研究
S J Zhang,G C Wang,K L Hua et al.
S J Zhang et al.
Objective: To construct a prediction model and website for the overall survival (OS) of gastric cancer patients after radical gastrectomy based on SHapley Additive exPlanations (SHAP) and machine learning models. Methods: This retrospective...
[Reasonable extent of No.12a lymph node dissection in laparoscopic surgery for locally advanced distal gastric cancer] [0.03%]
腹腔镜远端胃癌局部进展期淋巴结第12a组合理清扫范围探讨
B Ke,X N Wang,B G Wang et al.
B Ke et al.
Objective: To explore the appropriate extent of No.12a lymph node dissection in locally advanced distal gastric cancer patients. Methods: This study utilized a prospective observational research design, The inclusion criteria were: (1) age ...
[Comparison between laparotomy and laparoscopic operation for patients with gastric gastrointestinal stromal tumors: a multi-center observational study] [0.03%]
胃肠道间质瘤患者的开腹手术与腹腔镜手术的对比研究——多中心队列观察性研究
X Y Feng,F Y Zhou,R J Li et al.
X Y Feng et al.
Objective: To evaluate the safety, feasibility and efficacy of laparoscopic surgery for gastric gastrointestinal stromal tumors (G-GISTs). Methods: This study is a multicenter observational study. Between 1998 and 2017, 1072 patients with G...
[Clinical value and development prospects of surgical treatment for early gastric cancer] [0.03%]
早期胃癌外科治疗的临床价值与发展方向
Y H Sun,X D Gao
Y H Sun
While endoscopic techniques have propelled the development of early gastric cancer (EGC) treatment, surgical intervention remains irreplaceable due to its thoroughness in lymph node dissection. The limitations of preoperative staging, the r...
[Surgical treatment direction of gastroesophageal junction adenocarcinoma in the age of neoadjuvant immunotherapy] [0.03%]
免疫新辅助治疗时代的胃食管交界腺癌外科治疗方向
Z Zhu,X W Zhang,X Wang et al.
Z Zhu et al.
Adenocarcinoma of the gastroesophageal junction (AEG) represents a class of malignant digestive tract tumors with unique anatomical features and complex biological behaviors. Recent advancements in neoadjuvant immunotherapy have significant...
[Targeted regulation of tumor neovascularization to improve the efficacy of neoadjuvant immunotherapy and chemotherapy in locally advanced gastric cancer] [0.03%]
靶向调控肿瘤新生血管改善局部进展期胃癌新辅助免疫及化疗疗效的研究
Z G Zhu
Z G Zhu
In view of the abnormal network structure and function of newly formed blood vessels in tumor tissues, which often lead to an immunosuppressive state in the tumor microenvironment, resulting in varying degrees of limitations on the efficacy...
[New challenges to perioperative safety in the era of neoadjuvant immunotherapy for gastric cancer: distinguishing immune-related adverse events from postoperative complications] [0.03%]
[new challenges to perioperative safety in the era of neoadjuvant immunotherapy for gastric cancer: distinguishing irae from postoperative complications]新的胃癌新辅助免疫治疗时代下的围手术期安全挑战:区分免疫相关不良事件与术后并发症
M H Shi,Z Q Wu,J Dong et al.
M H Shi et al.
With the expanding use of immune checkpoint inhibitors (ICIs) in gastric cancer, surgical safety is facing new challenges. Perioperative immune-related adverse events (irAEs) can substantially overlap with postoperative complications in bot...