Risk factors for renal failure in patients with lupus nephritis: data from the spanish registry of glomerulonephritis [0.03%]
西班牙系膜毛细血管性肾小球肾炎登记注册处 lupus 患者终末期肾脏病的危险因素
Carmen Vozmediano,Francisco Rivera,Juan Manuel López-Gómez et al.
Carmen Vozmediano et al.
Background: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus. Data from national registries based on renal biopsies are scarce. The aim of our study was to analyze the demographic characterist...
Urinary matrix metalloproteinase activity in diabetic kidney disease: a potential marker of disease progression [0.03%]
糖尿病肾脏疾病尿基质金属蛋白酶活性改变及临床意义研究进展
Nagi Altemtam,Meguid El Nahas,Tim Johnson
Nagi Altemtam
Background: Progressive kidney fibrosis, associated with chronic kidney disease (CKD), results from an imbalance in extracellular matrix (ECM) homeostasis. Reduced matrix metalloproteinases (MMP) activity causing lower cl...
Amlodipine Reduces Inflammation despite Promoting Albuminuria in the Streptozotocin-Induced Diabetic Rat [0.03%]
氨氯地平减少炎症但可促进链脲佐菌素诱导的糖尿病大鼠尿白蛋白排泄量升高
Elizabeth R Flynn,David C Marbury,R Taylor Sawyer et al.
Elizabeth R Flynn et al.
Amlodipine reduces blood pressure; however, its effect in the diabetic kidney irrespective of its blood pressure-lowering effects is unclear. This study examined the effects of amlodipine (0, 5, 10 and 20 mg/kg; D(A0), D(A5), D(A10) and D(A...
Increased Prevalence and Severity of Coronary Artery Calcification in Patients with Chronic Kidney Disease Stage III and IV [0.03%]
III期和IV期慢性肾脏病患者冠状动脉钙化的患病率和严重程度增加
Maria Koukoulaki,Evangelos Papachristou,Christina Kalogeropoulou et al.
Maria Koukoulaki et al.
Background: Cardiovascular disease (CVD) is the main cause of mortality in patients with chronic kidney disease (CKD). The pathophysiology of coronary artery disease in CKD is multifactorial including, in addition to trad...
Skin autofluorescence: a pronounced marker of mortality in hemodialysis patients [0.03%]
皮肤自体荧光：血液透析患者的死亡率标志物
Esther G Gerrits,Helen L Lutgers,Gertie H W Smeets et al.
Esther G Gerrits et al.
Background: Accelerated formation and tissue accumulation of advanced glycation endproducts (AGEs), reflecting cumulative glycemic and oxidative stress, occur in age-related and chronic diseases like diabetes mellitus (DM...
Nephroprotective Effect of Echinodorus macrophyllus Micheli on Gentamicin-Induced Nephrotoxicity in Rats [0.03%]
迈克利大叶南莲属对大鼠庆大霉素致肾毒性的肾脏保护作用
Viviane Gomes Portella,Gustavo Pereira Cosenza,Lúcio Ricardo Leite Diniz et al.
Viviane Gomes Portella et al.
Background/aims: Leaves of Echinodorus macrophyllus (EM), from the Alismataceae family, have been used in Brazilian folk medicine for their anti-inflammatory and diuretic properties. In this work, the diuretic and nephrop...
Serum Beta 2-microglobulin/cystatin C index: a useful biomarker in lupus nephritis? [0.03%]
β2微球蛋白/半胱氨酸C指数：狼疮性肾炎的一个有用的生物标志物？
Marcus Vinicius Madureira Silva,Grace T Moscoso-Solorzano,Sonia K Nishida et al.
Marcus Vinicius Madureira Silva et al.
Background: Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease with frequent flares. Our aim was to evaluate the beta 2-microglobulin/cystatin C (β2M/CysC) index versus other markers as a pred...
DNA hypermethylation and inflammatory markers in incident Japanese dialysis patients [0.03%]
日本透析患者的DNA高甲基化和炎症标志物
Sawako Kato,Bengt Lindholm,Peter Stenvinkel et al.
Sawako Kato et al.
Background/aims: Inflammation is an established mortality risk factor in chronic kidney disease (CKD) patients. Although a previous report showed that uremic Caucasian patients with inflammation had signs of global DNA hy...
T A Facca,G Mastroianni Kirsztajn,A R Pereira et al.
T A Facca et al.
Background/aims: Preeclampsia (PE) is a cause of glomerulopathy worldwide. Urinary retinol-binding protein (RBP) is a marker of proximal tubular dysfunction, albuminuria is an endothelial injury marker, urine protein:crea...
Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey [0.03%]
脲苷酸盐相关性肾脏病的流行病学特征——一项全国范围调查的结果分析
Karl Lhotta,Sian E Piret,Reinhard Kramar et al.
Karl Lhotta et al.
Background/aims: Uromodulin-associated kidney disease (UAKD) is caused by uromodulin mutations and leads to end-stage renal disease. Our objective was to examine the epidemiology of UAKD. ...