Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease [0.03%]
调整阴离子间隙与慢性肾脏病患者的肾小球滤过率下降有关
Akashi Togawa,Satoko Uyama,Seiko Takanohashi et al.
Akashi Togawa et al.
Background: Metabolic acidosis is known to accelerate the progression of chronic kidney disease (CKD). However, whether undetermined anions as indicated by the adjusted anion gap (aAG) are associated with estimated glomer...
The Association between Fibroblast Growth Factor-23 and Vascular Calcification Is Mitigated by Inflammation Markers [0.03%]
炎症标志物可缓解成纤维细胞生长因子-23与血管钙化的关联性
Mohamed M Nasrallah,Amal R El-Shehaby,Noha A Osman et al.
Mohamed M Nasrallah et al.
Background: Fibroblast growth factor-23 (FGF-23) has been linked to vascular calcification, ventricular hypertrophy and mortality in chronic kidney disease (CKD), although these links may not be direct and independent. Si...
Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery [0.03%]
肥胖患者代谢手术后中性粒细胞明胶酶相关脂质运载蛋白对急性肾损伤的生物标志物价值研究
Maria Koukoulaki,Charalampos Spyropoulos,Panagiotis Hondrogiannis et al.
Maria Koukoulaki et al.
Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) has been identified as a biomarker of acute kidney injury (AKI) that could contribute to early diagnosis and effective management of AKI. The purpose of this...
Prevalence in the General Population of a CFH Sequence Variant Associated with Atypical Haemolytic Uraemic Syndrome in an Extensive Family from Southwest England [0.03%]
在英国西南部一个大家族中发现与非典型溶血性尿毒综合症相关的CFH序列变异体在普通人群中的发病率
Alexander J Hamilton,Carl B A Lyons,Timothy H J Goodship et al.
Alexander J Hamilton et al.
Background/aims: Twenty-five members of a family from the county of Devon in England have been affected by atypical haemolytic uraemic syndrome (aHUS) associated with a CFH mutation (c.3643C>G; p.Arg1215Gly). A 65-year-ol...
Variation of urate transport in the nephrons in subtypes of hyperuricemia [0.03%]
不同类型高尿酸血症患者肾小管尿酸转运的变化
Toru Nakamura,Rie Nishi,Tuneo Tanaka et al.
Toru Nakamura et al.
Background: Hyperuricemia cases (HU) can be classified into four subgroups by combining the two main causes of hyperuricemia, i.e. urate underexcretion and overproduction. These subgroups are as follows: underexcretion-ty...
The Prevalence of the Risk Factors for Atherosclerosis among Type 2 Diabetic Patients Is Greater in the Progressive Stages of Chronic Kidney Disease [0.03%]
2型糖尿病患者动脉粥样硬化危险因素患病率在慢性肾脏病进展期更高
Hiroyuki Ito,Shinichi Antoku,Masahide Furusho et al.
Hiroyuki Ito et al.
Background/aims: The prevalence of the risk factors for atherosclerosis, other than diabetes mellitus, among type 2 diabetic patients with different stages of chronic kidney disease (CKD) determined by glomerular filtrati...
Effects of different administration protocols on the plasma concentration of donepezil hydrochloride in dementia patients with stage 5 chronic kidney disease [0.03%]
不同给药方案对5期慢性肾病痴呆患者氯化多奈哌齐血浆浓度的影响
Chika Amano,Takafumi Ito,Masahiro Egawa et al.
Chika Amano et al.
The prevalence of chronic kidney disease (CKD) as well as Alzheimer's disease (AD) increases with age. With the aging of the population in Japan, there is an increasing likelihood that patients with CKD will receive donepezil hydrochloride ...
Case Reports
Nephron extra. 2013 Jun 8;3(1):59-65. DOI:10.1159/000351434 2013
Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis [0.03%]
缺氧可诱导肾小管上皮细胞间叶转化：肾移植纤维化的体外模型
Stephanie Zell,Roland Schmitt,Sandra Witting et al.
Stephanie Zell et al.
Background: The development of interstitial fibrosis and tubular atrophy is a common complication after kidney transplantation and is associated with reduced long-term outcome. The hallmark of tubulointerstitial fibrosis ...
Renoprotection and the Bardoxolone Methyl Story - Is This the Right Way Forward? A Novel View of Renoprotection in CKD Trials: A New Classification Scheme for Renoprotective Agents [0.03%]
肾保护与巴多索隆甲基的案例——这是否是前进的正确途径？慢性肾脏病试验中肾保护作用的新视角：对具有肾保护作用药物的新分类方法
Macaulay Onuigbo
Macaulay Onuigbo
In the June 2011 issue of the New England Journal of Medicine, the BEAM (Bardoxolone Methyl Treatment: Renal Function in CKD/Type 2 Diabetes) trial investigators rekindled new interest and also some controversy regarding the concept of reno...
Development of a chronic kidney disease model in C57BL/6 mice with relevance to human pathology [0.03%]
一种与人类病理相关的慢性肾脏病C57BL/6小鼠模型的建立与发展
Linghong Huang,Alessandra Scarpellini,Muriel Funck et al.
Linghong Huang et al.
Background: Genetically modified mice are used to investigate disease and assess potential interventions. However, research into kidney fibrosis is hampered by a lack of models of chronic kidney disease (CKD) in mice. Rec...