Aquaporin-2 promoter is synergistically regulated by nitric oxide and nuclear factor of activated T cells [0.03%]
一氧化氮和活化T细胞核因子协同调节水通道蛋白-2启动子
María F Albertoni Borghese,Layne M Bettini,Carlos H Nitta et al.
María F Albertoni Borghese et al.
Background/aims: We have previously shown that aquaporin-2 (AQP2) is down-regulated in the renal medulla of rats made hypertensive by chronic inhibition of nitric oxide synthase. It has been shown that AQP2 expression is ...
CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study [0.03%]
CYBA基因多态性与急性肾损伤不良结局的关联：前瞻性队列研究
Mary C Perianayagam,Hocine Tighiouart,Caroline M Nievergelt et al.
Mary C Perianayagam et al.
Background: NADPH oxidase is an important enzyme involved in the generation of reactive oxygen species in acute kidney injury (AKI). Its key subunit, p22(phox), is encoded by the highly polymorphic CYBA gene. ...
Early treatment with methylprednisolone pulse therapy combined with tonsillectomy for heavy proteinuric henoch-schönlein purpura nephritis in children [0.03%]
大剂量甲基强的松龙冲击联合扁桃体切除术治疗儿童重型蛋白尿过敏性紫癜肾炎疗效分析
Hiroaki Kanai,Emi Sawanobori,Anna Kobayashi et al.
Hiroaki Kanai et al.
Background: There is no clear consensus as to which patients with Henoch-Schönlein purpura nephritis (HSPN) at risk of a poor outcome should be treated and what therapeutic regimen should be used. ...
Determinants of outcome in non-septic critically ill patients with acute kidney injury on continuous venovenous hemofiltration [0.03%]
连续静脉-静脉血液滤过对非感染重症急性肾损伤患者结局的影响因素分析
Mark V Koning,Asselina A Roest,Marc G Vervloet et al.
Mark V Koning et al.
Background/aims: In view of ongoing controversy, we wished to study whether patient characteristics and/or continuous venovenous hemofiltration (CVVH) characteristics contribute to the outcome of non-septic critically ill...
Attenuation of Immune-Mediated Renal Injury by Telmisartan, an Angiotensin Receptor Blocker and a Selective PPAR-γ Activator [0.03%]
telmisartan通过免疫介导的肾损伤机制发挥保护作用：一种血管紧张素受体阻断剂和选择性过氧化物酶增殖激活受体γ活化剂的作用
Yuki Hamano,Takashi Okude,Osamu Yokosuka et al.
Yuki Hamano et al.
Background/aims: Anti-glomerular basement membrane (GBM) nephritis is characterized by activation of the renin-angiotensin system. This study aimed to determine the question of whether a temporary angiotensin II blockade ...
Maria Helena Vaisbich,Luciana Pache de Faria Guimaraes,Maria Heloisa Mazzola Shimizu et al.
Maria Helena Vaisbich et al.
Background/aims: Nephropathic cystinosis (NC) is a severe systemic disease and cysteamine improves its prognosis. Lysosomal cystine accumulation is the hallmark of cystinosis and is regarded as the primary defect due to m...
Crescentic glomerulonephritis in IgA multiple myeloma: a case report [0.03%]
IgA型多发性骨髓瘤 crescentic肾小球肾炎一例报告
Grace T Moscoso-Solorzano,Marcus V Madureira-Silva,Carlos Balda et al.
Grace T Moscoso-Solorzano et al.
Background: There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. ...
Case Reports
Nephron extra. 2011 Jan;1(1):69-72. DOI:10.1159/000331217 2011
Quantitative estimation of urate transport in nephrons in relation to urinary excretion employing benzbromarone-loading urate clearance tests in cases of hyperuricemia [0.03%]
尿酸排泄障碍的肾小管尿酸转运的定量估计——利尿醇负荷试验的应用研究
Toru Nakamura,Rie Nishi,Tuneo Tanaka et al.
Toru Nakamura et al.
Background: A four-component system for urate transport in nephrons has been proposed and widely investigated by various investigators studying the mechanisms underlying urinary urate excretion. However, quantitative dete...
Dosing of erythropoiesis-stimulating agents can be reduced by a new administration regimen [0.03%]
新型给药方案可减少促红细胞生成素的使用剂量
Bergur V Stefánsson,Börje Haraldsson,Ulf Nilsson
Bergur V Stefánsson
Background/aims: At our hemodialysis (HD) unit, we noted a drop in the treatment dose of erythropoietin-stimulating agents (ESAs) when the frequency of dose adjustment was reduced from weekly, where doses were withheld if...
Reference renal artery diameter is a stronger predictor of contrast-induced nephropathy than chronic kidney disease in patients with high cardiovascular risk [0.03%]
参考肾动脉直径比慢性肾脏病更强烈地预测高心血管风险患者的对比剂诱发的肾功能不全事件
Luca Zanoli,Stefania Rastelli,Carmelita Marcantoni et al.
Luca Zanoli et al.
Introduction: The incidence of contrast-induced nephropathy (CIN) increases in high cardiovascular risk patients. Chronic kidney disease (CKD) is a known risk factor for CIN development. In a previous report, we demonstra...