Two Blood Monocytic Biomarkers (CCL15 and p21) Combined with the Mini-Mental State Examination Discriminate Alzheimer's Disease Patients from Healthy Subjects [0.03%]
两种血液单核细胞生物标志物(CCL15和p21)与简易智能精神状态检查联合鉴别阿尔茨海默病患者和健康人
Tanja Hochstrasser,Josef Marksteiner,Michaela Defrancesco et al.
Tanja Hochstrasser et al.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder. In AD, monocytes migrate across the blood-brain barrier and differentiate into microglia, are linked to inflammatory responses and display ...
Giorgio Giaccone,Laura Orsi,Chiara Cupidi et al.
Giorgio Giaccone et al.
The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the ...
Positive FP-CIT SPECT (DaTSCAN) in Clinical Alzheimer's Disease - An Unexpected Finding? [0.03%]
临床阿尔茨海默病患者中的假阳性FP-CIT(SPECT、DATSCAN)检查结果——一个意外的发现？
Verena Bittner,Gerhard Ullrich,Markus Thormann et al.
Verena Bittner et al.
Clinically, Alzheimer's disease (AD) is by far the most common cause of dementia. Criteria for the diagnosis of dementia with Lewy bodies (DLB) are highly specific but not at all sensitive, which is reflected by the higher number of DLB cas...
The chinese (cantonese) montreal cognitive assessment in patients with subcortical ischemic vascular dementia [0.03%]
缺血性血管性痴呆患者中山大学认知评估量表(C-MoCA)的临床应用研究
Jin-Song You,Ri-Zhao Chen,Fo-Ming Zhang et al.
Jin-Song You et al.
Background: Subcortical ischemic vascular dementia (SIVD) has been proposed as the most frequent subtype of vascular cognitive impairment. The aim of this study was to evaluate the psychometric properties of the Chinese (...
Evidence for a Common Founder and Clinical Characteristics of Japanese Families with the MAPT R406W Mutation [0.03%]
日本MAPT R406W突变家系的共同祖先证据及其临床特征
Takeshi Ikeuchi,Toru Imamura,Yasuhiro Kawase et al.
Takeshi Ikeuchi et al.
Background/aim: Mutations in MAPT cause frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). Patients with the MAPT R406W mutation were reported to show phenotypic heterogeneity in different ethnic...
Factors associated with a depressive disorder in Alzheimer's disease are different from those found for other dementia disorders [0.03%]
阿尔茨海默病伴抑郁障碍的相关因素与其他类型痴呆不同
Maria Lage Barca,Knut Engedal,Jerson Laks et al.
Maria Lage Barca et al.
Background: This study explores factors associated with depression in Alzheimer's disease (AD) compared with mild cognitive impairment (MCI) and other dementia disorders. ...
The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness [0.03%]
N末端脑利钠肽前体评估精神病老年人血管疾病的使用效果研究
Karin Nilsson,Lars Gustafson,Björn Hultberg
Karin Nilsson
Background: Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment. ...
Lack of Association between Apolipoprotein E Polymorphism with Age at Onset of Subcortical Vascular Dementia [0.03%]
载脂蛋白E多态性与亚皮质血管性痴呆发病年龄无关
Hye Guk Ryu,Sung-Won Youn,Oh Dae Kwon
Hye Guk Ryu
Background and purpose: The relationship between apolipoprotein E (ApoE) and onset of vascular dementia remains controversial. The aim of this study was to evaluate the relationship between ApoE polymorphism and the onset...
Polymorphism in apoA1 Influences High-Density Lipoprotein Cholesterol Levels but Is Not a Major Risk Factor of Alzheimer's Disease [0.03%]
载脂蛋白A1多态性影响高密度脂蛋白胆固醇水平但不是阿尔茨海默病的主要危险因素
Mohamed Ali Smach,Hayet Edziri,Bassem Charfeddine et al.
Mohamed Ali Smach et al.
Background: Apolipoprotein A1 (apoA1) is the major apolipoprotein constituent of the high-density lipoprotein (HDL) and is involved in reverse cholesterol transport. Variation in the apoA1 gene might influence the functio...
Criminal manifestations of dementia patients: report from the national forensic hospital [0.03%]
痴呆患者的犯罪表现：国家精神疾病医院的报告
Jeong-Min Kim,Kon Chu,Keun-Hwa Jung et al.
Jeong-Min Kim et al.
Background/aims: Some dementia patients have profound behavioral and psychological symptoms which might cause legal violation. We illustrate clinical and criminal characteristics of dementia patients who had been incarcer...