Role of APOE and Age at Enrollment in the Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT) [0.03%]
APOE基因及入组年龄在阿尔茨海默氏症抗炎预防试验（ADAPT）中的作用
Lea T Drye,Peter P Zandi
Lea T Drye
Background: The Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT) tested whether non-steroidal anti-inflammatory drugs (NSAIDs) can prevent Alzheimer's disease (AD). The results were null. We analyzed ADAPT d...
Changes in phospholipid composition of erythrocyte membrane in Alzheimer's disease [0.03%]
阿尔茨海默病患者红细胞膜磷脂组成的变化
Shinji Oma,Shiro Mawatari,Kazuyuki Saito et al.
Shinji Oma et al.
Background: There are several reports indicating a decrease of ethanolamine plasmalogen (pl-PE) in brain tissues and in serum of patients with Alzheimer's disease (AD). The present study aimed to examine the composition o...
Video Rating in Neurodegenerative Disease Clinical Trials: The Experience of PRION-1 [0.03%]
进行性海绵状脑病(PRION-1)临床试验中的视频评估法：经验分享
Christopher Carswell,Michael Rañopa,Suvankar Pal et al.
Christopher Carswell et al.
Background/aims: Large clinical trials including patients with uncommon diseases involve assessors in different geographical locations, resulting in considerable inter-rater variability in assessment scores. As video reco...
Cognitive factors affecting free recall, cued recall, and recognition tasks in Alzheimer's disease [0.03%]
阿尔茨海默病患者自由回忆、提示回忆和再认任务的认知因素
Takashi Yamagishi,Takuya Sato,Atsushi Sato et al.
Takashi Yamagishi et al.
Background/aims: Our aim was to identify cognitive factors affecting free recall, cued recall, and recognition tasks in patients with Alzheimer's disease (AD). ...
CIBIC Plus-J Assessment Using a Videotaped Method in Alzheimer's Disease Patients [0.03%]
阿尔茨海默病患者使用视频方法进行CIBIC Plus-J评估
Yu Nakamura,Mikiko Usui,Takashi Nishikawa et al.
Yu Nakamura et al.
Background/aims: CIBIC plus-J is the Japanese language version equivalent to CIBIC plus. Variability of CIBIC plus-J arises among raters in accordance with their experience and their memories of patients' conditions at ba...
Cerebrovascular function in aging and dementia: a systematic review of transcranial Doppler studies [0.03%]
衰老和痴呆中的脑血管功能：经颅多普勒研究的系统评价
Hannah A D Keage,Owen F Churches,Mark Kohler et al.
Hannah A D Keage et al.
Background/aim: The contribution of cerebrovascular dysfunction to the manifestation of dementia and cognitive decline in late life is gaining increased attention. We aimed to systematically review evidence for associatio...
Yamaguchi Facial Expression-Making Task in Alzheimer's Disease: A Novel and Enjoyable Make-a-Face Game [0.03%]
山口造脸任务在阿尔茨海默病中的应用：一种新颖且有趣的造脸游戏
Tomoharu Yamaguchi,Yohko Maki,Haruyasu Yamaguchi
Tomoharu Yamaguchi
Background: To assess the ability to make emotional facial expressions, we newly developed the Yamaguchi facial expression-making task (Y-FEMT). Method: ...
Urinary Urgency Medications May Compromise Discrete rather than Global Cognitive Skills [0.03%]
控尿药物可能会损害离散而非全局性认知能力
Marilee Monnot,Elliott Ross
Marilee Monnot
Background/aims: Prior research about cognitive problems associated with the use of urinary urgency medication (UUM) has reported mixed results that suggest procedures and/or assessments may need to be refined. ...
Elizabeth E Galletta,Anthony H Lequerica,Scott R Pekrul et al.
Elizabeth E Galletta et al.
Background/aims: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients ...
Association of chronic obstructive pulmonary disease with cognitive decline in very elderly men [0.03%]
慢性阻塞性肺疾病与非常老年的男性认知功能下降的关系
Guoqing Zhou,Jinxia Liu,Fang Sun et al.
Guoqing Zhou et al.
Aim: To determine the change in cognitive function in very elderly men with chronic obstructive pulmonary disease (COPD) over a 3-year period relative to age-and education-matched controls. ...