Pedro Bullon,Luis E Pavillard,Rafael de la Torre-Torres
Pedro Bullon
One of the main steps in the development of the life in the earth is multicellularity. It enables cell differentiation and the development of morphological structures within an organism and is an essential factor in how to recognize friendl...
Fengying Xu,Zongmei Wen,Xueying Shi et al.
Fengying Xu et al.
Lung diseases are common and significant causes of illness and death around the world. Inflammasomes have emerged as an important regulator of lung diseases. The important role of IL-1 beta and IL-18 in the inflammatory response of many lun...
Traumatic Injury [0.03%]
创伤损伤
Borna Relja,Johann-Philipp Horstmann
Borna Relja
Traumatic injury as one of the world's most relevant but neglected health concerns results in modulated inflammasome activity, which is closely linked to the development of post-injury complications. Cytokine-producing capacity of cells is ...
Lung Diseases [0.03%]
肺疾病
Saleela M Ruwanpura,Sarah Rosli,Michelle D Tate
Saleela M Ruwanpura
Inflammasomes are large innate cytoplasmic complexes that play a major role in promoting inflammation in the lung in response to a range of environmental and infectious stimuli. Inflammasomes are critical for driving acute innate immune res...
Eduardo A Albornoz,Trent M Woodruff,Richard Gordon
Eduardo A Albornoz
Neuroinflammation is a common pathological feature in almost all neurological diseases and is a response triggered as a consequence of the chronic activation of the innate immune response in the CNS against a variety of stimuli, including i...
Gerardus P J van Hout,Lena Bosch
Gerardus P J van Hout
Cardiovascular disease (CVD) is the number one cause of death worldwide. The pathogenesis of various disease entities that comprise the area of CVD is complex and multifactorial. Inflammation serves a central role in these complex aetiologi...
Elísabet Alcocer-Gómez,Beatriz Castejón-Vega,Macarena López-Sánchez et al.
Elísabet Alcocer-Gómez et al.
Inflammasomes are multiprotein complexes formed and activated after exposure to pathogenic microbes and host danger signals that control the maturation and production of IL-1β and IL-18. Their implication in different diseases such as card...
José E Belizário,Joel Faintuch
José E Belizário
The gastrointestinal (GI) tract is the residence of trillions of microorganisms that include bacteria, archaea, fungi and viruses. The collective genomes of whole microbial communities (microbiota) integrate the gut microbiome. Up to 100 ge...
Diana Moreira,Jérôme Estaquier,Anabela Cordeiro-da-Silva et al.
Diana Moreira et al.
A complex network that embraces parasite-host intrinsic factors and the microenvironment regulated the interaction between a parasite and its host. Nutritional pressures exerted by both elements of this duet thus dictate this host-parasite ...
Cláudia S Rodrigues,Cláudia F Campos,Cristina Cunha et al.
Cláudia S Rodrigues et al.
In recent years, the renewed interest in immune cell metabolism has driven the emergence of a research field aimed at studying the role of metabolic processes during innate and adaptive immune responses. Although the specific requirements o...