Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates [0.03%]
巨噬细胞pyroptosis介导新生儿高氧性肺损伤炎症反应
Zikun Tu,Haiyan Guo,Yajing Gao et al.
Zikun Tu et al.
Background: Hyperoxia plays a key role in the development of bronchopulmonary dysplasia (BPD), a chronic lung disease of preterm infants. This study aimed to investigate the role of NLRP3/caspase-1/gasdermin D (GSDMD)-med...
Daria Bogdanova,Mikhail Y Samsonov,Svetlana Lebedeva et al.
Daria Bogdanova et al.
Sterile inflammation with ensuing immune-mediated kidney damage has been implicated in pathophysiology of acute and chronic kidney diseases. Disinhibition of interleukin 1 (IL-1) signaling triggers local inflammation of renal tissue and may...
Malakoplakia among kidney transplant recipients: case series and literature review [0.03%]
肾移植受者中的肠膨出病：病例系列和文献综述
Ali B Abbasi,Gerardo Gamino,Alan Zambeli-Ljepović et al.
Ali B Abbasi et al.
We report two cases of malakoplakia after kidney transplant, a rare granulomatous condition that occurs primarily in immunocompromised patients and his thought to occur due to incomplete clearance of phagocytized bacterial residue by macrop...
Lenvatinib versus bevacizumab when combined with PD-1/L1 inhibitor and hepatic arterial infusion chemotherapy in unresectable hepatocellular carcinoma [0.03%]
LENVA替尼与贝伐珠单抗联合PD-1/L1抑制剂及肝动脉灌注化疗治疗不可切除性肝细胞癌患者的研究
Lichang Huang,Yujie Xu,Na Liu et al.
Lichang Huang et al.
Introduction: The combination of anti-angiogenic agents, PD-1/L1 inhibitors, and hepatic arterial infusion chemotherapy (HAIC) has emerged as an important strategy for unresectable hepatocellular carcinoma (uHCC), yet com...
Comparative Study
Frontiers in immunology. 2025 May 23:16:1573098. DOI:10.3389/fimmu.2025.1573098 2025
The role of fibroblast-neutrophil crosstalk in the pathogenesis of inflammatory diseases: a multi-tissue perspective [0.03%]
成纤维细胞-中性粒细胞相互作用在炎症性疾病发病机制中的作用：多组织视角
Chen Cai,Lanxi Guan,Chenhao Wang et al.
Chen Cai et al.
Neutrophil-fibroblast crosstalk drives inflammatory pathology across organ systems through both shared and tissue-specific mechanisms. This review synthesizes evidence from skin, lung, gut, cardiovascular, joint, sinus, and oral diseases, r...
Mitochondrial metabolic rescue in post-COVID-19 syndrome: MR spectroscopy insights and precision nutritional therapeutics [0.03%]
基于磁共振光谱的见解和精确营养治疗在新冠后遗症中的线粒体代谢复苏研究
Li-Zhen Chen,Qi Cai,Peng-Fei Zheng
Li-Zhen Chen
Post-COVID-19 Condition (PCC), impacting 30-90% of survivors, is characterized by persistent fatigue and metabolic dysfunction, often linked to underlying mitochondrial impairment. This review examines current evidence on mitochondrial-targ...
Prognostic value of systemic inflammation response index in patients with glioma: a meta-analysis [0.03%]
胶质瘤患者系统性炎症反应指数的预后价值：一项meta分析研究
Yizhen Jiang,Lin Zhou
Yizhen Jiang
Background: The systemic inflammation response index (SIRI) has been investigated for its prognostic relevance in patients with glioma; however, findings remain inconsistent. Therefore, this meta-analysis aimed to clarify...
The pivotal role of inflammatory factors in glaucoma: a systematic review [0.03%]
炎症因子在青光眼发病机制中的关键作用：系统性综述
Bin Lin,Dongkan Li
Bin Lin
Glaucoma, a leading cause of irreversible vision loss, is becoming more prevalent with the aging population, burdening patients, families, and society. In the past, the role of inflammatory factors in its pathogenesis was overlooked. This s...
Biological mechanisms of pulmonary inflammation and its association with seropositive rheumatoid arthritis [0.03%]
肺部炎症的生物学机制及其与类风湿性关节炎的相关性
Peiyue Yang,Yuqing Song,Mingwei Li
Peiyue Yang
Although the pathogenesis of seropositive rheumatoid arthritis (RA) remains unclear, studies suggest that pulmonary inflammation-related biological mechanisms play a significant role in its development. This review thoroughly explores the m...
Innate immune cell barrier-related genes inform precision prognosis in pancreatic cancer [0.03%]
胰腺癌精准预后中的固有免疫细胞屏障相关基因
Qiang Luo,Tingting Jiang,Dacheng Xie et al.
Qiang Luo et al.
Introduction: Pancreatic cancer (PC) remains a lethal malignancy with limited treatment options. The role of innate immune cell barrier-related genes in PC prognosis is poorly defined. This study aimed to identify prognos...