Case Report: Anti-ADAM23 antibody: an overlooked autoantibody against VGKC-complex in autoimmune encephalitis [0.03%]
案例报告：抗ADAM23抗体：自身免疫性脑炎中被忽视的针对VGKC复合物的自身抗体
Pinfei Ni,Lin Bai,Nan Jiang et al.
Pinfei Ni et al.
Objectives: Antibodies against voltage-gated potassium channel (VGKC) complexes include anti-LGI1 and anti-CASPR2. Anti-ADAM23 antibodies have not been previously reported in autoimmune encephalitis (AE). ...
GPR65 is a novel immune biomarker and regulates the immune microenvironment in lung adenocarcinoma [0.03%]
GPR65是肺腺癌免疫生物标志物并调节肿瘤免疫微环境
Hanxu Zhou,Zhi Chen,Shuang Gao et al.
Hanxu Zhou et al.
Background: The tumor microenvironment (TME) plays a crucial role in the progression of lung adenocarcinoma (LUAD), and it may serve as the best prognostic predictor of LUAD. GPR65 is an extracellular pH-sensing G protein...
Negative associations of age and lifestyle factors with the antibody response to the COVID-19 vaccine BNT162b2 in health workers from Spain [0.03%]
西班牙卫生工作者接种BNT162b2新冠疫苗后抗体反应较差的相关因素分析
Luis Sarabia de Ardanaz,Esther Serrano-Conde,Ana Fuentes et al.
Luis Sarabia de Ardanaz et al.
Introduction: Despite the high efficacy of the anti-coronavirus disease 2019 (COVID-19) BNT162b2 vaccine (Comirnaty®, Pfizer-BioNTech), variability in the antibody titers following vaccination has been described. However...
Cytokine concentration in peripheral blood of patients with childhood obesity [0.03%]
儿童肥胖患者外周血细胞因子浓度测定
Jia Mai,Min Wang,Ying Guo et al.
Jia Mai et al.
Introduction: Obesity is marked by chronic inflammation, with research showing notable changes in cytokines. However, systematic investigations into cytokine level changes are still lacking. This study compared the concen...
The concordance of swelling/tenderness with ultrasound-detected inflammatory lesions in patients with psoriatic arthritis [0.03%]
银屑病关节炎患者中肿胀/触痛与超声检测的炎症损伤的一致性分析
Xiaoying Sun,Yan Geng,Zhibo Song et al.
Xiaoying Sun et al.
Background: Psoriatic arthritis (PsA) is a complex and varied inflammatory condition that can cause arthritis, enthesitis, dactylitis, and spondylitis. In recent years, ultrasound (US) imaging has emerged as a valuable ad...
Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response [0.03%]
基于mild新冠感染后中位随访时间为28个月的患者的PBMCs综合转录组评估，发现JAK/STAT信号传导上调和免疫反应持续存在
Serena Fineschi,Joakim Klar,Juan Ramon Lopez Egido et al.
Serena Fineschi et al.
Background: Post-acute sequelae of SARS-CoV-2 infection (PASC), also known as post-COVID-19 condition (here abbreviated as post-COVID) is an escalating global health issue. The aim of our study was to investigate the mech...
Control of MAIT cell functions by cytokines in health and disease [0.03%]
细胞因子在健康和疾病状态下对MAIT细胞功能的调控作用
Laetitia Camard,Elisabetta Bianchi,Lars Rogge
Laetitia Camard
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that express a semi-invariant T cell receptor (TCR). These cells predominantly reside in tissues, such as the liver, lung, skin and the gastrointestinal tract. MAIT cells c...
Mapping of RORγt+ dendritic cells in human tissues establishes their preferential niche in adult lymph nodes [0.03%]
RORγt+树突细胞在人体组织中的分布表明其主要分布在成人淋巴结中
Silvia Lonardi,Francisco Ma Bianchetto-Aguilera,Matilde Monti et al.
Silvia Lonardi et al.
Background: The retinoic-acid-receptor-related orphan receptor gamma t (RORγt) isoform is required for the development of lymphoid organs, T-helper 17 cells (Th17), and innate lymphoid cells (ILC3s). Recent data in mouse...
Spontaneous partial resolution of autoimmune-mediated brain MRI abnormalities before immunotherapy in anti-metabotropic glutamate receptor 5 encephalitis: a case report [0.03%]
抗代谢型谷氨酸受体5脑炎患者接受免疫治疗前自身免疫性脑MRI异常的部分自发改善：病例报告
Jingjiong Chen,Xin Tang,Linran Wang et al.
Jingjiong Chen et al.
Anti-metabotropic glutamate receptor 5 (mGluR5) encephalitis is a rare autoimmune disorder characterized by varied neurological symptoms, often associated with limbic syndromes. We report the case of a 57-year-old female who presented with ...
Is adiponectin involved in morphea pathogenesis? - first observational study [0.03%]
脂联素参与硬化病发病机制吗？- 首个观察研究
Adriana Polańska,Aleksandra Wiktoria Bratborska,Michał J Kowalczyk et al.
Adriana Polańska et al.
Background: Morphea is a chronic inflammatory condition characterized by fibrosis of the skin and/or subcutaneous tissues. Adiponectin is an adipokine known for its anti-inflammatory and antifibrotic properties. Lower lev...
Observational Study
Frontiers in immunology. 2025 May 30:16:1588439. DOI:10.3389/fimmu.2025.1588439 2025