Unveiling the dual role of circulating tumor cells in colorectal cancer immunotherapy: a comprehensive review of biomarker utility and immune microenvironment crosstalk [0.03%]
循环肿瘤细胞在结直肠癌免疫治疗中的双重作用：生物标志物应用和免疫微环境相互作用的全面综述
Yifan Feng,Gang Liu,Qixue Cai et al.
Yifan Feng et al.
Colorectal cancer (CRC) has the highest incidence in the Asia-Pacific region, accounting for 51.8% of global cases. Despite early screening methods like colonoscopy, CT, and MRI, 20-25% of patients are diagnosed at advanced stages, with som...
Hazem Aboaid,Taimur Khalid,Abbas Hussain et al.
Hazem Aboaid et al.
Head and neck squamous cell carcinoma (HNSCC) remains a challenging malignancy with suboptimal survival outcomes despite advances in surgery, radiotherapy, and chemotherapy. Immunotherapy, particularly immune checkpoint inhibitors (ICIs) ta...
Effect of immune checkpoint inhibitor therapy on biventricular mechanics in cancer patients over a short-term follow-up: a systematic review [0.03%]
免疫检查点抑制剂治疗对癌症患者双心室力学的短期影响：系统性回顾
Andrea Sonaglioni,Antonino Bruno,Gian Luigi Nicolosi et al.
Andrea Sonaglioni et al.
Background: Immune checkpoint inhibitors (ICI) have demonstrated a survival benefit in various cancer types. A few numbers of imaging studies have recently measured myocardial strain parameters in cancer patients before a...
Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance [0.03%]
关于调节性T细胞和I型干扰素在阿巴卡韦诱导的免疫耐受及过敏反应中的作用机制的新认识
Marco Cardone,Hratch M Baghdassarian,Maryam Khalaj et al.
Marco Cardone et al.
Introduction: Clinical use of several small molecule drugs may lead to severe T-cell-mediated idiosyncratic drug hypersensitivity reactions (iDHR) linked to HLA alleles, including abacavir (ABC) with HLA-B*57:01. Due to s...
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p [0.03%]
METTL3介导的m6A修饰通过miR-208a-5p调控D-半乳糖诱导的皮肤成纤维细胞衰老
Gaoxiang Huang,Sainan Sun,Mingde Liao et al.
Gaoxiang Huang et al.
Introduction: As the most abundant epitranscriptomic modification, N6-methyladenosine (m6A) critically influences aging and age-related pathologies. However, its regulatory interplay with microRNAs (miRNAs) in skin aging ...
IL-1beta expressing neutrophil extracellular traps in Legionella pneumophila infection [0.03%]
铜绿假单胞菌感染中IL-1β诱导的中性粒细胞胞外陷阱形成及其机制研究
Myrto Koutantou,Theocharis Konstantinidis,Dimosthenis Chochlakis et al.
Myrto Koutantou et al.
Introduction: Legionella pneumophila is the causative agent of Legionnaires' Disease (LD), an atypical pneumonia with potentially fatal outcome. Neutrophils, the first line of defense, infiltrate the lungs during L. pneum...
Immune response dynamics of SARS-CoV-2 vaccination in chronic lymphocytic leukemia individuals: a descriptive analysis [0.03%]
慢性淋巴细胞白血病个体的SARS-CoV-2疫苗免疫反应动态：描述性分析
Clara Sánchez-Menéndez,Alejandro Zurdo,Magdalena Corona et al.
Clara Sánchez-Menéndez et al.
Chronic lymphocytic leukaemia (CLL) is a lymphoproliferative disorder of abnormal B-lymphocytes. Due to immune deregulation and therapy-related factors, CLL individuals face increased infection risks, making vaccination a priority. Although...
Impact of postoperative depression and immune-inflammatory biomarkers on the prognosis of patients with esophageal cancer receiving minimally invasive esophagectomy: a retrospective cohort study based on a Chinese population [0.03%]
中国人群食管癌患者微创食管切除术后抑郁和免疫炎症生物标志物对其预后影响的队列研究
Pei-Xin Tan,Lin-Xin Wu,Shuang Ma et al.
Pei-Xin Tan et al.
Background: Patients with esophageal cancer (EC) frequently experience depression following neoadjuvant therapy and surgery, a condition that may trigger systemic inflammation, suppress antitumor immunity, and alter immun...
Pituitary dysfunction with eosinophilic granulomatosis with polyangiitis presenting with diabetes insipidus: a case report and review of the literature [0.03%]
糖尿病.insipidus并多血管炎伴嗜酸性粒细胞肉芽肿1例及文献复习
Aifei Zhang,Xiaoxia Liu,Pengjia Wu et al.
Aifei Zhang et al.
Central diabetes insipidus secondary to hypophysitis in eosinophilic granulomatosis with polyangiitis (EGPA) is very rare, and this article summarizes one case reported from our site as well as two previously reported patients with EGPA, bo...
Safety and efficacy of sintilimab versus pembrolizumab in the treatment of advanced or recurrent pediatric malignancies: a real-world study in China [0.03%]
斯鲁利单抗与帕博利珠单抗治疗晚期或复发性儿童恶性肿瘤的安全性和疗效：中国真实世界研究
Lei Mao,Mengzhen Li,Linnan Wu et al.
Lei Mao et al.
Background: Programmed death receptor 1 (PD-1) inhibitors have shown durable response and mild adverse events in adult malignancies. However, study on PD-1 inhibitors in pediatric patients remains limited, and a direct co...
Comparative Study
Frontiers in immunology. 2025 Jun 6:16:1608844. DOI:10.3389/fimmu.2025.1608844 2025