Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice [0.03%]
牧草鹅观花粉源二半乳糖二脂酰甘油促进小鼠过敏反应
Nestor González Roldán,Lars P Lunding,Yukari Fujimoto et al.
Nestor González Roldán et al.
Introduction: Grass pollen triggers nearly 30% of bronchial allergic asthma cases. While most Q8 research focuses on pollen allergens, pollen lipids may also influence allergic reactions. Previous studies demonstrated tha...
Enrique Aguado,Mikel M Arbulo-Echevarria,Ewoud B Compeer
Enrique Aguado
Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis [0.03%]
胸腺素α1通过免疫调节减轻急性重症胰腺炎患者的炎症和防止感染：系统评价和Meta分析
Yong Tian,Jiaqi Yao,Yihan Ma et al.
Yong Tian et al.
Background: Immune and inflammatory disorders are part of the complex pathophysiological processes that exacerbate severe acute pancreatitis (SAP) and subsequent infection. Thymosin alpha 1 (Tα1) is an important immunomo...
Bile acid receptors regulate the role of intestinal macrophages in inflammatory bowel disease [0.03%]
胆酸受体调节肠巨噬细胞在炎症性肠病中的作用
Hongjie Yang,Xianhong Shi,Beibei Wang et al.
Hongjie Yang et al.
Many factors, including genetic vulnerability, barrier function, intestinal immune cells, and intestinal microbiota, may combine to affect the occurrence and progression of inflammatory bowel disease (IBD). Through targeting bile acid recep...
Interferons and Toxoplasma gondii shape PD-L1 regulation in retinal barrier cells: the critical role of proteases [0.03%]
干扰素和弓形虫调节视网膜屏障细胞PD-L1的作用：蛋白酶的关键作用
Benjamin Geiller,Camila Cevallos,Iuliia Tsybenko et al.
Benjamin Geiller et al.
Introduction: The apicomplexan parasite Toxoplasma gondii establishes chronic infection in the central nervous system, including the retina, causing ocular toxoplasmosis (OT). This persistence relies on a fine balance bet...
Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice [0.03%]
大麻素通过不同的代谢途径抑制年轻和年老小鼠B细胞的激活
Zhanna Yekhtin,Dmytro Petukhov,Iman Khuja et al.
Zhanna Yekhtin et al.
Objective: B lymphocytes play a crucial role in immunity but also contribute to the pathogenesis of various diseases. Cannabis plants produce numerous biologically active compounds, including cannabinoids. The two most st...
Commentary: Molecular and immunological features of TREM1 and its emergence as a prognostic indicator in glioma [0.03%]
评论：TREM1的分子和免疫学特征及其作为胶质瘤预后指标的研究进展
Jihao Xue,Zhilin Luo,Tao Wang et al.
Jihao Xue et al.
Brain-derived blood biomarkers in multiple sclerosis-current trends and beyond [0.03%]
多发性硬化症中的脑源性血液生物标志物-当前趋势及未来展望
Shamundeeswari Anandan,Karina Maciak,Regina Breinbauer et al.
Shamundeeswari Anandan et al.
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the nervous system and a main cause of neurological disability in young adults. Most disease-modifying therapies are administrated as long-term maintenance t...
Integrated multi-omics and machine learning reveals immune-metabolic signatures in osteoarthritis: from bulk RNA-seq to single-cell resolution [0.03%]
整合多组学和机器学习揭示软骨退变的免疫代谢特征：从bulk RNA-seq到单细胞分辨率
Hui He,Xiumei Zhao,Bo Zhang et al.
Hui He et al.
Purpose: The aim of this study was to investigate the activation of immune-metabolic pathways in osteoarthritis (OA) and their role in disease progression. We employed differential expression analysis and Gene Set Enrichm...
Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications [0.03%]
调节性T细胞的转录指印：确保细胞治疗应用中的质量控制
Zhang Cheng,Li-Jie Wang,Yuchi Honaker et al.
Zhang Cheng et al.
Introduction: The success of regulatory T cell (Treg) therapies depends on the source of Treg and the quality of the Treg manufacturing product that maintains Treg identity. Commonly used methods to identify Treg, includi...