Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses [0.03%]
高致病性韩国谱系B型PRRSV-2的免疫病理特征：关于毒力指标和宿主免疫反应的新见解
Gyeong-Seo Park,Seung-Chai Kim,Hwan-Ju Kim et al.
Gyeong-Seo Park et al.
Introduction: Porcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most economically devastating pathogens in swine, primarily due to its extensive genetic diversity and lineage-dependent pathoge...
Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch [0.03%]
肺纤维化再探：脂纤维细胞向炎性脂纤维细胞向活化的肌成纤维细胞可逆转换的炎症动力学
Georgios-Dimitrios Panagiotidis,Esmeralda Vasquez-Pacheco,Xuran Chu et al.
Georgios-Dimitrios Panagiotidis et al.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by excessive extracellular matrix (ECM) deposition and irreversible lung damage. A key driver of disease progression is the phenotypic shi...
Bibliometric and visual analysis of global crc circular RNA research 2015-2023 [0.03%]
2015-2023年全球结直肠癌环形RNA研究的 bibliometri 和可视化分析
Jian Feng Bin,Long Fei Chen,Yan Wang et al.
Jian Feng Bin et al.
Background: Colorectal cancer (CRC) is the third highest malignant tumor in the world in terms of incidence rate, accounting for about 10% of all cancer cases and the second leading cause of cancer related deaths. Timely ...
AAV-HBV mouse model replicates the intrahepatic immune landscape of chronic HBV patients at single-cell level [0.03%]
基于单细胞水平的腺相关病毒HBV感染小鼠模型再现慢性乙肝患者肝脏免疫图谱
Nádia Conceição-Neto,Wim Pierson,Qinglin Han et al.
Nádia Conceição-Neto et al.
Introduction: Unresolved hepatitis B virus (HBV) infection leads to a progressive state of HBV-specific immune dysfunctionality that characterizes chronic infection. The immune-competent adeno associated virus (AAV)-HBV m...
The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis [0.03%]
血浆蛋白质组揭示了与PR3-ANCAs阳性及MPO-ANCAs阳性血管炎相关的不同信号通路
Erik Hellbacher,Vincent van Hoef,Alina Johansson et al.
Erik Hellbacher et al.
Objective: Despite recent advances, the pathophysiological mechanisms underlying anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) remain incompletely understood, and comparative proteomic analyses...
Single-cell analysis of peripheral blood and pleural effusion reveals functional diversity of γδ T cells in tuberculosis infection [0.03%]
单细胞测序揭示肺结核感染中外周血和胸腔积液γδT细胞的功能多样性
Yanjun Feng,Yu Chen,Wanying Zhang et al.
Yanjun Feng et al.
Introduction: Tuberculosis is a contagious airborne disease caused by the Mycobacterium tuberculosis infection. γδ T cells are closely associated with TB infection; however, the specific role of γδ T cells in the immu...
Editorial: A new perspective in immune polymorphism (the HLA, KIR, and LILR genes) [0.03%]
社论：免疫多态性（HLA、KIR和LILR基因）的新视角
Seik-Soon Khor,Martin Maiers,Jason Krawic et al.
Seik-Soon Khor et al.
A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors [0.03%]
一项全基因敲低shRNA筛选研究发现NK细胞活化受体的新配体
Paolo Romania,Loredana Cifaldi,Paula Gragera et al.
Paolo Romania et al.
Introduction: Natural Killer (NK) cells play a key role in both innate and adaptive immune responses against viruses and tumor cells. Their function relies on the dynamic balance between activating and inhibitory signals,...
Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics [0.03%]
整合分析Ewing肉瘤中T细胞相关标志物揭示其预后特征及免疫特性odynamicsimmune动态免疫特性之间的关系不太准确，调整为：整合分析Ewing肉瘤中T细胞相关标志物揭示其预后特征及免疫动态
Umair Ali Khan Saddozai,Chenxu Liu,Fei Yan et al.
Umair Ali Khan Saddozai et al.
Background: Ewing sarcoma (ES) is a rare and aggressive pediatric bone malignancy with poor prognosis, driven by therapy-resistant tumor microenvironments (TME). The TME plays a critical role in tumor progression through ...
Recent advances in the genetics and innate immune cells of bullous pemphigoid [0.03%]
大疱性天疱疮的遗传和先天免疫细胞研究进展近述
Xiaoli Yang,Panling Wei,Zaixing Wang
Xiaoli Yang
Bullous pemphigoid (BP) is a common autoimmune subepidermal blistering disease that primarily affects elderly patients. The pathogenesis of BP is complex, involving genetic, immune, and environmental factors. Recent evidence suggests that m...