Dietary inflammation: a potential driver of atopic dermatitis?-Evidence from KNHANES 2017-2023 [0.03%]
饮食炎症：潜在的特应性皮炎驱动因素？—来自2017-2023年KNHANES的证据
Kaiyue Tan,Nanren Sun,Dongyang Wang et al.
Kaiyue Tan et al.
Background: The global incidence of atopic dermatitis (AD) has risen significantly in recent decades, with trends showing spatial and temporal coupling with dramatic changes in dietary habits during industrialisation. Alt...
C3d-targeted complement inhibitors to correct complement dysregulation in aHUS patients [0.03%]
用于靶向C3d以纠正aHUS患者补体失调的补体抑制剂
Valeria Guaschino,Donata Santarsiero,Sara Gastoldi et al.
Valeria Guaschino et al.
Atypical hemolytic uremic syndrome (aHUS) is a rare and severe thrombotic microangiopathy caused by genetic or acquired abnormalities leading to activation of the complement alternative pathway on cell surfaces. This process leads to endoth...
Antibody treatment of hepatocellular carcinoma: a review of current and emerging approaches [0.03%]
肝细胞癌的抗体治疗：当前和新兴方法综述
Sherif A El-Kafrawy,Mostafa S Elkafrawy,Esam I Azhar et al.
Sherif A El-Kafrawy et al.
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related deaths worldwide, underscoring the urgent need for innovative therapeutic strategies. Antibody-based therapies have emerged as a transformative approach, offering spec...
Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics [0.03%]
基于血液转录组学的非侵入性诊断炎症性肠病的生物标志物发现
Mohammad Hossein Derakhshan Nazari,Mahsa Ghorbaninejad,Shabnam Shahrokh et al.
Mohammad Hossein Derakhshan Nazari et al.
Introduction: Colonoscopy remains the gold standard for diagnosing inflammatory bowel disease (IBD) even though it is an invasive and costly procedure. To enable non-invasive diagnosis, we aimed to identify blood-based tr...
Case Report: Guselkumab treatment for sintilimab-exacerbated psoriasis in a cancer patient [0.03%]
病例报告：对一名癌症患者的 sintilimab 加剧的银屑病进行 guselkumab 治疗
Jianhao Ke,Meiliang Guo,Xuan Zhao et al.
Jianhao Ke et al.
Psoriasis is a chronic inflammatory skin disease associated with multisystem comorbidities and impaired mental health. The lesions are typically characterized by sharply demarcated, erythematous plaques covered with silvery scales. Treatmen...
Total neoadjuvant immunochemotherapy for proficient mismatch repair or microsatellite stable locally advanced rectal cancer [0.03%]
高效MMR或微卫星稳定型局部晚期直肠癌的新辅助化疗免疫治疗
Xing Li,Ligong Tang,Fangyuan Cheng et al.
Xing Li et al.
Objective: Our goal was to assess the efficacy of integrating PD-1 inhibitors with total neoadjuvant treatment (iTNT) in enhancing complete response (CR) rates and the propensity for watch-and-wait (WW) strategies in pati...
Thyroid disorders as predictors of cemiplimab efficacy in recurrent/metastatic cervical cancer: real-world evidence from Poland [0.03%]
波兰真实世界证据：甲状腺疾病是复发/转移性宫颈癌cemiplimab疗效的预测因素
Renata Pacholczak-Madej,Maja Lisik-Habib,Radosław Mądry et al.
Renata Pacholczak-Madej et al.
Introduction: Immune checkpoint inhibitors have improved survival in patients with recurrent or metastatic cervical cancer (r/mCC), yet reliable predictors of treatment efficacy remain undefined. Immune-related adverse ev...
Observational Study
Frontiers in immunology. 2025 Jun 20:16:1604826. DOI:10.3389/fimmu.2025.1604826 2025
Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei [0.03%]
布氏 melioidosis 异素和同素免疫策略的比较研究
Sergei S Biryukov,Christopher K Cote,Christopher P Klimko et al.
Sergei S Biryukov et al.
Introduction: Melioidosis is a major cause of disease and mortality in endemic tropical regions, and the etiologic agent, Burkholderia pseudomallei, is being isolated increasingly from an expanded range of environmental a...
Comparative Study
Frontiers in immunology. 2025 Jun 20:16:1596265. DOI:10.3389/fimmu.2025.1596265 2025
Exercise-related immune gene signature for hepatocellular carcinoma: machine learning and multi-omics analysis [0.03%]
基于机器学习和多组学分析的肝癌运动相关免疫基因标志物研究
Cheng Pu,Lei Pu,Xiaoyan Zhang et al.
Cheng Pu et al.
Background: Exercise is known to regulate the immune system. However, its prognostic value in hepatocellular carcinoma (HCC) remains largely unknown. Obje...
A retrospective efficacy and safety study of pembrolizumab/cetuximab neoadjuvant therapy in locally advanced hypopharyngeal cancer [0.03%]
派姆单抗/西妥昔单抗新辅助治疗局部晚期下咽癌疗效及安全性的回顾性研究
Guangnan Yao,Xiaobo Wu,Hanqing Lin et al.
Guangnan Yao et al.
Purpose: The primary objective of this study was to retrospectively assess the efficacy and safety profiles of two neoadjuvant regimens combining either pembrolizumab or cetuximab with paclitaxel and cisplatin in patients...