BRICS sequential therapeutic regimen as first-Line treatment for PD-L1-negative metastatic non-small cell lung cancer patients harboring EGFR/ALK wild-type status: a retrospective study [0.03%]
一项针对EGFR/ALK野生型PD-L1阴性转移性非小细胞肺癌患者的回顾性研究：BRICS序贯治疗方案作为一线治疗
Jianxin Chen,Jian Wang,Weiqiang Fang et al.
Jianxin Chen et al.
Background: Patients with PD-L1-negative, EGFR/ALK wild-type metastatic non-small cell lung cancer (NSCLC) exhibit limited responses to immune checkpoint inhibitors (ICIs). This study evaluates the BRICS regimen-a sequent...
Co-expression of IL-15/IL-15Ra complex enhances NKG2D-CAR T cell-mediated anti-pancreatic cancer immunity by activating the JAK/STAT5 signaling pathway [0.03%]
IL-15/IL-15Ra共表达通过激活JAK/STAT5信号通路增强NKG2D-CAR-T细胞抗胰腺癌免疫能力
Yiran Chen,Chenxu Jin,Dandan Guo et al.
Yiran Chen et al.
The application of CAR T therapy has significantly improved the efficacy of hematological tumors. However, there are still some challenges in the treatment of solid tumors, mainly because the complex immune microenvironment affects the prol...
Correction: Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells [0.03%]
纠正：动脉粥样硬化斑块中的蛋白质氨基甲酰化与尿毒症和疾病进展相关，并且主要定位在泡沫细胞中
Valeria Saar-Kovrov,Aleksandra Pawlowska,Adrien Guillot et al.
Valeria Saar-Kovrov et al.
[This corrects the article DOI: 10.3389/fimmu.2025.1532250.]. Keywords: atherosclerosis; carbamylation; foam...
Published Erratum
Frontiers in immunology. 2025 Jun 23:16:1637511. DOI:10.3389/fimmu.2025.1637511 2025
Short-term heavy drinking in a non-human primate model skews monocytes toward a hypo-inflammatory phenotype [0.03%]
短期过度饮酒使非人灵长类动物单核细胞向低炎症表型偏移
Madison B Blanton,Hami Hemati,Qi Qiao et al.
Madison B Blanton et al.
Introduction: Alcohol use is prevalent in the United States (US), with ~80% of persons over 12 years old reporting alcohol consumption in 2023 and ~10% of those individuals developing alcohol use disorder (AUD). Acute and...
The battle between bacterial infection and autophagy in aquatic animals [0.03%]
水产动物细菌感染与自噬的博弈机制研究进展
Qi Wang,He Xu,Jiaxue Jin et al.
Qi Wang et al.
Autophagy is a conserved cellular degradative pathway that has been demonstrated to play a crucial role in the innate immune response to combat infection with a range of pathogenic bacteria via xenophagy. Although this process has been well...
The tumor microenvironment across four dimensions: assessing space and time in cancer biology [0.03%]
肿瘤微环境的四维研究：从时空角度评估癌症生物学
Christina R Larson,Ayushi Mandloi,Satwik Acharyya et al.
Christina R Larson et al.
The tumor microenvironment is heterogeneous, structurally complex, and continually evolving, making it difficult to fully capture. Common dissociative techniques thoroughly characterize the heterogeneity of cellular populations but lack str...
Research progress on the role of dendritic cells in glioma during 1992-2024: a bibliometric analysis [0.03%]
1992-2024年胶质瘤领域树突状细胞研究的文献计量分析
Linglei Zhu,Linpeng Zhang,Shuqi Han et al.
Linglei Zhu et al.
Background: Gliomas represent the most prevalent primary neoplasms of the central nervous system. Activating an immune response by dendritic cells is pivotal in glioma immunotherapy. This study offers a comprehensive bibl...
The role of notch signaling pathway and non-coding RNAs in cancer and inflammation: progress, therapeutic insights, and future directions [0.03%]
Notch信号通路和非编码RNA在癌症及炎症中的作用：进展、治疗启示与未来方向
Rong-Zu Nie,Hang Wang,Shuang-Shuang Wang et al.
Rong-Zu Nie et al.
The Notch signaling pathway and non-coding RNAs (ncRNAs) play significant roles in regulating key cellular processes such as cancer progression, metastasis, and drug resistance. This article systematically reviews the interactions between t...
Rituximab as the first-line treatment in newly diagnosed systemic lupus erythematosus [0.03%]
利妥昔单抗治疗新诊断的系统性红斑狼疮患者
Haiting Wang,Liling Zhao,Shaoying Yang et al.
Haiting Wang et al.
Objectives: Rituximab (RTX) has been commonly used for the treatment of patients with severe or refractory systemic lupus erythematosus (SLE), yet real-world data concerning RTX as the first-line treatment in newly diagno...
Editorial: Cellular and host immune responses in the context of dual viral infection [0.03%]
编辑部：双重病毒感染下的细胞及宿主免疫反应
Mohamed Mahdi,Vartika Srivastava
Mohamed Mahdi