Matching-adjusted indirect comparison of tislelizumab plus lenvatinib versus sintilimab plus bevacizumab biosimilar as first-line treatment for unresectable hepatocellular carcinoma [0.03%]
替雷利珠单抗联合乐伐替尼与信迪利单抗联合贝伐珠单抗生物类似药作为不可切除肝细胞癌一线治疗的匹配调整间接比较研究
Kunyuan Wang,Chang Liu,Xiaoling Song et al.
Kunyuan Wang et al.
Background: Programmed cell death-1/programmed cell death-ligand 1 (PD-[L]1) inhibitors plus bevacizumab (or biosimilars) or tyrosine kinase inhibitors (TKIs) have been widely used for the first-line treatment of patients...
Comparative Study
Frontiers in immunology. 2025 Jun 23:16:1594935. DOI:10.3389/fimmu.2025.1594935 2025
MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis [0.03%]
微小核糖核酸调节肺纤维化中肺泡巨噬细胞的稳态及其功能
Nirmal Parajuli,Yi Yao,Namir Khalasawi et al.
Nirmal Parajuli et al.
Introduction: Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of ...
GMMA-based vaccine candidates against invasive nontyphoidal salmonellosis elicit bactericidal antibodies against a panel of epidemiologically relevant Salmonellae [0.03%]
基于GMMA的疫苗候选者可针对一系列流行病学相关的沙门氏菌产生杀菌型抗体
Daniele De Simone,Marika Pinto,Maria Grazia Aruta et al.
Daniele De Simone et al.
Systemic disease caused by nontyphoidal Salmonella (NTS) represents a major cause of death and morbidity, especially in young children in sub-Saharan Africa. No licensed vaccine is yet available, and an increase in antimicrobial resistance ...
Systematic pan-cancer analysis identifies PKNOX1 as a potential prognostic and immunological biomarker and its functional validation [0.03%]
系统泛癌分析确定PKNOX1作为一个潜在的预后和免疫生物标志物及其功能验证
Kan Liu,Yongkang Xu,Ye Mao et al.
Kan Liu et al.
Background: PBX/knotted1 homeobox 1 (PKNOX1), also known as PREP1, is a homeodomain transcription factor that has been reported to be involved in the progression of gastric adenocarcinoma and non-small cell lung cancer. H...
PLGA nanoparticles as an efficient carrier in Toxoplasma GAP45: a more effective vaccine against acute toxoplasmosis than traditional ones [0.03%]
聚乳酸-乙醇酸纳米粒作为弓形虫GAP45 DNA疫苗的高效递送载体：一种比传统疫苗更有效的急毒性弓形虫病疫苗
Pan Zhou,YanLi Yu,WeiYu Qi et al.
Pan Zhou et al.
Introduction: Toxoplasma gondii (T. gondii), as a strict intracellular parasite, can infect nearly all mammals, including humans, posing significant threats to public health. Toxoplasmosis in animals also leads to substan...
Sarah A Wedemeyer,Ann V Griffith
Sarah A Wedemeyer
Thymic B cells comprise a heterogenous population of cells localized primarily within the thymic medulla, a region populated by professional antigen-presenting cells (APCs) including dendritic cells, medullary thymic epithelial cells (mTECs...
Non-coding RNAs as key regulators in hepatitis B virus-related hepatocellular carcinoma [0.03%]
非编码RNA在乙肝病毒相关肝癌发生发展中的作用及机制研究
Prasanna Srinivasan Ramalingam,Liming Zhang,Md Sadique Hussain et al.
Prasanna Srinivasan Ramalingam et al.
Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remains a significant global health challenge due to its high prevalence and poor prognosis. Recent advances have revealed that non-coding RNAs (ncRNAs), including microRNAs, lo...
Correction: Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology [0.03%]
关于使用靶向蛋白质组学Olink技术筛查胎盘介导的胎儿生长受限疾病的潜在蛋白生物标志物的研究更正通知
Xinyao Zhou,Wuqian Wang,Luan Chen et al.
Xinyao Zhou et al.
[This corrects the article DOI: 10.3389/fimmu.2025.1542034.]. Keywords: Olink proteomics platform; biomarker...
Published Erratum
Frontiers in immunology. 2025 Jun 23:16:1632381. DOI:10.3389/fimmu.2025.1632381 2025
From syndromic clues to diagnosis: understanding CARD11-driven disorders [0.03%]
从综合征线索到诊断：理解CARD11驱动的疾病
Elena García-Martínez,María Teresa Schiaffino,Marisa Di Natale et al.
Elena García-Martínez et al.
CARD11 is primarily expressed in hematopoietic tissues and lymphocytes and plays a crucial role in the proper activation of B and T cells in response to antigen recognition. Pathogenic variants in the CARD11 gene result in a broad spectrum ...
The safety and effectiveness of sintilimab versus camrelizumab, both plus targeted drugs, in advanced hepatocellular carcinoma [0.03%]
特瑞普利单抗与卡瑞利珠单抗联合仑伐替尼治疗晚期肝细胞癌的安全性和有效性：随机、开放性、多中心II期研究
Chenglong Zhao,Qiongni Zhu,Xiaoyan Qian et al.
Chenglong Zhao et al.
Objectives: We aimed to evaluate the effectiveness and safety of sintilimab versus camrelizumab, both plus targeted drugs, for advanced hepatocellular carcinoma (HCC) in the real world. Then the effectiveness was compared...
Comparative Study
Frontiers in immunology. 2025 Jun 23:16:1585956. DOI:10.3389/fimmu.2025.1585956 2025