A set of plasmatic microRNA related to innate immune response highly predicts the onset of immune reconstitution inflammatory syndrome in tuberculosis co-infected HIV individuals (ANRS-12358 study) [0.03%]
一组与先天性免疫反应相关的血清miRNA可高度预测结核病合并艾滋病患者免疫重建炎症综合征的发生（ANRS-12358研究）
Polidy Pean,Ratana Meng,Eliott Benichou et al.
Polidy Pean et al.
Background: After initiation of combination antiretroviral treatment (cART), HIV-1/tuberculosis coinfected patients are at high risk of developing tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IR...
Correlation between microneutralization test and a multiplexed immunoassay for evaluation of monkeypox and vaccinia virus antibodies before and after smallpox vaccination [0.03%]
改良微中和试验与评价天花疫苗接种前后猴痘病毒和痘苗病毒抗体的多重免疫分析的相关性研究
Serena Marchi,Giulia Piccini,Edmond J Remarque et al.
Serena Marchi et al.
Introduction: Monkeypox (mpox), an endemic zoonotic viral disease in Central and Western Africa, gained international attention in 2022 when clade IIb of the Monkeypox virus (MPXV) spread outside Africa, prompting the Wor...
Kidney transplant outcomes in HLA desensitized patients with pretransplant CDC and/or FCM positive crossmatches [0.03%]
针对CDC和/或FCM阳性交叉配型受者的肾脏移植HLA耐受诱导效果及移植物存活率分析
Johan Noble,Céline Dard,Diane Giovannini et al.
Johan Noble et al.
Background: Kidney transplant (KT) candidates with very high calculated panel reactive alloantibody (cPRA >95%) have limited chances to receive an HLA-matched transplant unless they undergo pretransplant desensitization. ...
Characterization of the clinical relevance and hypoallergenic peptides of the newly evidenced major allergen Hum j 1 [0.03%]
新型主要过敏原Hum j 1的临床相关性及低变应原性肽段特征分析
Ya-Li Cheng,Qiong Li,Yong-Shi Yang et al.
Ya-Li Cheng et al.
Background: Humulus japonicus (HJ) pollen is a predominant autumn allergen in northern China. Two decades ago, a 10 kDa protein termed Hum j 1 was proposed as a major allergen, but its uncertainty hindered its clinical ap...
Assessing disease phenotypes in Behçet's syndrome: insights from a multiple correspondence analysis [0.03%]
贝赫切特综合征的疾病表型评估：多重对应分析的启示
Rosaria Talarico,Federica Di Cianni,Antonello Sulis et al.
Rosaria Talarico et al.
Introduction: Behçet's syndrome (BS) is a rare systemic vasculitis. Clinical manifestations in BS are frequently clustered rather than discrete, and the concept that distinct clinical phenotypes may exist in BS has recen...
Single-cell transcriptomic and m6A methylation analyses reveal platelet-mediated immune regulatory mechanisms in sepsis [0.03%]
单细胞转录组和m6A甲基化分析揭示血小板介导的脓毒症免疫调控机制
Weiwei Qian,Yuanyuan Liu,Xinyang Zhao et al.
Weiwei Qian et al.
Objective: Sepsis is a systemic inflammatory response syndrome triggered by infection, characterized by high clinical heterogeneity and complex immunopathological mechanisms. Immune dysregulation plays a central role in i...
A fish-specific antimicrobial peptide Ms Piscidin2 inactivates MSRV and confers protection in largemouth bass [0.03%]
一种鱼特异性抗菌肽Ms Piscidin2可使MSRV失活并在鲤鱼中发挥保护作用
Chenjie Fei,Ziwen Wang,Yang Hu et al.
Chenjie Fei et al.
Antimicrobial peptides (AMPs) represent an evolutionarily conserved component of innate immunity with broad-spectrum antimicrobial and antiviral activities. However, the antiviral potential of fish-specific piscidins against emerging aquati...
Machine learning combined multi-omics analysis to explore key oxidative stress features in systemic lupus erythematosus [0.03%]
机器学习结合多组学分析探索系统性红斑狼疮氧化应激关键特征
Hongwei Zhou,Xiaoqing Li,Yanyu Zhang et al.
Hongwei Zhou et al.
Objective: Metabolic dysregulation and redox imbalance in immune cells are key drivers of systemic lupus erythematosus (SLE) pathogenesis. This study explores critical oxidative stress (OS) features and their interrelatio...
Serum exosomal microRNA profiling reveals a down-regulation of hsa-miR-124-3p in patients with severe acne [0.03%]
血清外泌体微小核糖核酸谱系检测发现严重痤疮患者hsa-miR-124-3p下调
Shujuan Zhang,Yimin Liang,Manqi Xia et al.
Shujuan Zhang et al.
Background: Acne is a chronic inflammatory skin disease affecting pilosebaceous unit. However, its specific mechanism remain incompletely understood. Obje...
Altered co-expression patterns of synovial fluid proteins related to the immune system and extracellular matrix organization in late stage OA, compared to non-OA controls [0.03%]
与无骨关节炎对照相比，晚期骨关节炎滑液蛋白的相关免疫系统和细胞外基质组织共表达模式发生变化
Jenny Lönsjö,Martin Rydén,Aleksandra Turkiewicz et al.
Jenny Lönsjö et al.
Objective: Synovial fluid contains proteins that may have been released from surrounding tissues, our aim was to gain new insights into the proteomic profiles of human synovial fluid in knees with and without osteoarthrit...