The L-shaped association between weight-adjusted-waist index and all-cause mortality in individuals with psoriasis: results from NHANES database retrospective cohort study [0.03%]
基于NHANES数据库的回顾性队列研究中银屑病患者的体重指数与腰围调整后的L形关联与全因死亡率之间的关系
Jiawen Chen,Xueting Zeng,Niu Xiang et al.
Jiawen Chen et al.
Background: While obesity is widely recognized as a robust risk factor contributing to both the onset and exacerbation of psoriasis-a chronic, immune-mediated skin disorder-the relationship between the Weight-Adjusted-Wai...
Case Report: Immune checkpoint inhibitor-induced myositis without elevated creatine kinase [0.03%]
免疫检查点抑制剂诱导的肌炎（血清肌酸激酶正常）——个例报告
Klajdi Begaj,Raphael Wilhelm,Alisa Lepper et al.
Klajdi Begaj et al.
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced cancers like malignant melanoma. However, they can lead to a range of immune-related adverse events (irAEs), impacting various organ systems. Among these, myo...
Pyroptosis as a therapeutic target in preeclampsia: current research and future directions [0.03%]
胎盘炎性细胞焦亡的发病机制及治疗靶点研究进展
Yongchun Zhu,Yuting Xiang,Sathiskumar Swamiappan et al.
Yongchun Zhu et al.
Preeclampsia (PE) is a severe pregnancy-specific disorder characterized by new-onset hypertension and proteinuria after the 20th week of gestation, posing significant threats to maternal and fetal health. Globally, approximately 4 million w...
The distinct biological role of JAML positions it as a promising target for treating human cancers and a range of other diseases [0.03%]
JAML独特的生物学作用使其成为治疗人类癌症及其他多种疾病的一个很有前景的靶点
Zhilin Dong,Ning Liu,Meili Sun
Zhilin Dong
Junctional adhesion molecule-like protein (JAML), a member of the junctional adhesion molecule (JAM) family, is widely expressed in various cells. This review examines the progress made in understanding JAML, beginning with its discovery an...
Organ of Corti macrophages: a distinct group of cochlear macrophages with potential roles in supporting cell degeneration and survival [0.03%]
柯替器巨噬细胞：耳蜗中具有潜在支持细胞退变和存活作用的特殊巨噬细胞群
Mengxiao Ye,Celia Zhang,Dalian Ding et al.
Mengxiao Ye et al.
Macrophages are the primary immune cells in the cochlea, essential for maintaining cochlear homeostasis and orchestrating inflammatory responses to pathological events. Although these cells have been found in various parts of the cochlea, t...
Association between triglyceride-glucose index and subclinical carotid atherosclerosis in systemic lupus erythematosus: a cohort-based study [0.03%]
甘油三酯-葡萄糖指数与中国系统性红斑狼疮队列患者亚临床颈动脉粥样硬化的关联分析
Wenhui Xie,Minjie Li,Hong Huang et al.
Wenhui Xie et al.
Objective: To investigate the association between triglyceride-glucose (TyG) index and carotid atherosclerosis in patients with systemic lupus erythematosus (SLE). ...
Progress in combination vaccines and the co-administration of influenza virus and SARS-CoV-2 vaccines [0.03%]
联合疫苗进展和流感病毒及SARS-CoV-2疫苗联合接种的进展
Chengyu Hu,Chenguang Niu,Xiaohui Li et al.
Chengyu Hu et al.
COVID-19 and seasonal influenza have taken a huge toll on the global economy and global health. Given the potential of COVID-19 to transform into a chronic epidemic akin to seasonal influenza, the influenza virus and SARS-CoV-2 will continu...
Epidemiology, molecular typing, microbiome-immune interactions and treatment strategies of endometrial cancer: a review [0.03%]
子宫内膜癌的流行病学、分子分型、菌群-免疫互作及治疗策略：综述
Bingyan Liang,Jia Tan,Jia Li et al.
Bingyan Liang et al.
This review focuses on the field of endometrial cancer. Since 2020, there have been 417,367 new cases of endometrial cancer diagnosed globally and 97,370 deaths reported. Endometrial cancer ranks second in terms of incidence among female ge...
Megan C Purl,Alexandria Shick,Robert J Canter et al.
Megan C Purl et al.
Novel cellular therapies have shown practice changing results in a range of hematologic malignancies, though success against solid tumors has been limited. Key factors limiting success of these therapies against solid tumors are homing to t...
The potential immunomodulatory role of human milk oligosaccharides in prevention of viral infections and development of asthma in early life [0.03%]
人类乳糜寡糖在预防生命早期病毒感染和哮喘发病中的潜在免疫调节作用
Vera Rijks,Marit Zuurveld,Johan Garssen et al.
Vera Rijks et al.
Around 10% of the Western population is diagnosed with asthma, and this percentage is only expected to increase in the coming years. Allergic asthma often develops during early infancy and is characterized by chronic pulmonary type 2 inflam...