Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer's disease [0.03%]
整合生物信息学和机器学习方法揭示氧化应激和糖酵解相关基因为阿尔茨海默病的治疗靶点和药物候选物
Fatima Noor,Sidra Aslam,Ignazio S Piras et al.
Fatima Noor et al.
Background: Alzheimer's disease (AD), the most common form of dementia, has treatments that slow but do not stop cognitive decline. Additional treatments are based on its pathogenic mechanisms are needed. Evidence has lon...
Senescence-associated signature based on immunotherapy response sequencing reveals PPIL3 as target for bladder cancer treatment and prognosis prediction [0.03%]
基于免疫治疗反应测序的衰老相关签名揭示了PPIL3是用于膀胱癌治疗和预后预测的目标分子
Kaixuan Du,Ning Kang,Yuda Lin et al.
Kaixuan Du et al.
Background: Bladder cancer (Bca) remains a major genitourinary malignancy with unmet needs in immunotherapy optimization. Despite advancements in immune checkpoint inhibitors (ICIs), challenges persist, including low resp...
The prognostic and clinicopathological value of HALP score in non-small cell lung cancer [0.03%]
HALP评分在非小细胞肺癌预后及临床病理特征中的价值分析
Qin Li,Mengqi Chen,Huaqin Zhao et al.
Qin Li et al.
Objective: The prognostic role of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in non-small cell lung cancer (NSCLC) has been widely reported, but the results remain controversial. Therefore, we aim to e...
Correction: Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: results from a phase Ia/Ib clinical trial [0.03%]
纠正：博安 mustardine 联合移植后环磷酰胺对年轻患者T细胞丰富半相合骨髓移植后免疫重建的影响：一项Ia/Ib期临床试验的结果
Forrest L Baker,Jessica Stokes,Megan J Cracchiolo et al.
Forrest L Baker et al.
[This corrects the article DOI: 10.3389/fimmu.2025.1568862.]. Keywords: T-cells; TCR-β sequencing; bendamus...
Published Erratum
Frontiers in immunology. 2025 Jun 26:16:1633590. DOI:10.3389/fimmu.2025.1633590 2025
Correction: Acute exacerbation of anti-Ha antibody-positive antisynthetase syndrome-associated interstitial lung disease: a case report [0.03%]
抗Ha抗体阳性氨基酰-tRNA合酶综合征相关间质性肺疾病的急性加重：1例报告校正稿
Yinying Li,Junyi Ke,Shu Huang et al.
Yinying Li et al.
[This corrects the article DOI: 10.3389/fimmu.2025.1614777.]. Keywords: ILD; anti-Ha antibody; anti-syntheta...
Published Erratum
Frontiers in immunology. 2025 Jun 26:16:1647113. DOI:10.3389/fimmu.2025.1647113 2025
Plasma polymeric immunoglobulin receptor exacerbates lung injury in Klebsiella pneumoniae-induced pneumosepsis [0.03%]
铜绿假单胞菌诱导的脓毒症中等离子体多聚免疫球蛋白受体加重肺损伤
Shuaiwei Wang,Hao Fu,Xiaoqing Li et al.
Shuaiwei Wang et al.
Background: Polymeric immunoglobulin receptors (pIgR) may enhance mucosal immunity or worsen an infection through transcytosis of polymeric immunoglobulins or infectious pathogens. The function of plasma pIgR in infection...
Extracellular vesicles: molecular messengers and new therapeutic targets in acute myocardial infarction [0.03%]
细胞外囊泡：急性心肌梗死中的分子信使和新的治疗靶点
Hao Wu,Jinyi Xue,Qiuyu Liu et al.
Hao Wu et al.
Extracellular vesicles (EVs) are nanoscale particles secreted by cells, encapsulating a variety of biomolecules, and have emerged as significant players in the pathophysiology of acute myocardial infarction (AMI). These vesicles exhibit bot...
Association between protein diet score and colorectal adenomas risk: a prospective study [0.03%]
基于前瞻性队列的饮食蛋白质摄入与结直肠腺瘤风险关联的病例巢式病例对照研究
Yangpiaoyi Shi,Zhiquan Xu,Wanhao Tan et al.
Yangpiaoyi Shi et al.
Objective: Given the significantly increased risk of colorectal adenoma in middle-aged and elderly populations, identifying modifiable risk factors remains a priority. While dietary protein is an essential nutrient in hum...
Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model [0.03%]
纳米脂蛋白颗粒（NLP）疫苗可保护BALB/c小鼠免受耶尔森氏菌鼠疫菌气溶胶攻击
Sergei S Biryukov,Amy Rasley,Michael L Davies et al.
Sergei S Biryukov et al.
Introduction: Yersinia pestis is the etiological agent of plague, a disease that remains a concern as demonstrated by recent outbreaks in Madagascar. Infection with Y. pestis results in a rapidly progressing illness that ...
Amplification of select autonomous HERV loci and surrounding host gene transcription in monocytes from patients with post-acute sequelae of COVID-19 [0.03%]
新冠病毒后急性 sequelaes患者的单核细胞中选择性自主HERV位点及其周围宿主基因转录的放大作用研究
Hyunmin Koo,Casey D Morrow
Hyunmin Koo
Background: The human genome contains approximately 3,200 near full-length autonomous human endogenous retroviral (HERV) genomes distributed across the 23 chromosomes. These autonomous HERV proviral genomes include long t...