Breaking the one-dimensional paradigm: why cardiovascular research needs a multi-systems revolution [0.03%]
打破一维观念：为什么心血管研究需要多系统革命
Sebastien Chaigne
Sebastien Chaigne
Neutrophil extracellular trap markers predict thrombotic risk in patients with hyperhomocysteinemia: development and validation of a predictive model [0.03%]
中性粒细胞胞外诱捕物标志物可预测高同型半胱氨酸血症患者的血栓风险：预测模型的建立与验证
Lifan Shao,Shujie Zhang,Zhenyu Wang et al.
Lifan Shao et al.
Background: Venous thromboembolic diseases pose a serious threat to human health, and their pathogenesis is closely associated with the abnormal activation of neutrophils and neutrophil extracellular traps (NETs). However...
Challenges in diagnosing and treating chronic exertional compartment syndrome: perspective from a student nurse with lower extremity pain [0.03%]
慢性劳损隔室综合征的诊断与治疗挑战：一位有下肢疼痛的学生护士的观点
Madelyne Marbel,Robert Knoerl
Madelyne Marbel
Chronic Exertional Compartment Syndrome (CECS) is an uncommon yet debilitating condition that causes activity-induced pain due to increased pressure within muscle compartments. While typically diagnosed through dynamic intercompartmental pr...
Integrated transcriptomic and proteomic analyses identify the TLR2-CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity [0.03%]
整合转录组和蛋白质组分析确定TLR2-CXCR4轴在模拟微重力条件下调控内皮细胞迁移中的作用
Xiaodong Qin,Ruonan Wang,Chengfei Li et al.
Xiaodong Qin et al.
Simulated microgravity profoundly alters endothelial function, particularly cell migration. However, the mechanosensitive molecular pathways involved remain incompletely understood. In this study, we performed integrated transcriptomic and ...
The multi-protective role of dietary betaine in largemouth bass (Micropterus salmoides): coordinating antioxidant, inflammatory, and metabolic homeostasis under high-fat diet stress [0.03%]
饲喂甜菜碱对高脂饮食胁迫下蓝鳃太阳鱼抗氧化、抗炎和代谢稳态的多保护作用研究
Yi-Jia Liu,Jian Guo,Chang-Da Li et al.
Yi-Jia Liu et al.
Introduction: Intensive aquaculture frequently utilizes high-fat diets (HF) as a cost-effective strategy, yet this practice often induces hepatic steatosis, oxidative stress, and chronic inflammation in carnivorous fish. ...
The predictive value of the FT3/FT4 ratio for the severity of coronary artery disease in patients with acute coronary syndrome [0.03%]
FT3/FT4比值对急性冠脉综合征患者冠心病严重程度的预测价值研究
Hui He,Zhen Zhang,Long Xia et al.
Hui He et al.
Background and aims: Thyroid hormones critically regulate cardiovascular homeostasis, with thyroid dysfunction established as an independent risk factor for coronary artery disease. While free triiodothyronine (FT3) to fr...
A meta-analysis of the effects of high-intensity interval training on circulatory system-related indicators in sedentary populations [0.03%]
久坐人群高强度间歇训练对心血管系统影响的meta分析研究
Guoshuai Li,Depeng Dong
Guoshuai Li
Objective: This study systematically evaluated the effects of high-intensity interval training (HIIT) on circulatory indicators in sedentary populations. Following the framework of systematic review and meta-analysis, it ...
Current perspectives and trends on the role of mitochondria in renal ischemia-reperfusion injury from 2005 to 2024: a bibliometric analysis and literature review [0.03%]
2005-2024年肾脏缺血再灌注损伤中线粒体作用的现状和趋势：文献计量分析与综述
Rui Yan,Yalong Zhang,Zewen Li et al.
Rui Yan et al.
Background: Renal ischemia-reperfusion injury (RIRI) represents a leading cause of acute kidney injury (AKI). Mitochondria, serving as the central organelles for cellular energy metabolism and signal transduction, play a ...
Paddle selection and adjustment for young male kayakers: the science behind the art [0.03%]
论桨：年轻男子皮划艇运动员的选配与调整——艺术背后的科学
Rui António Fernandes,Fernando Alacid,Beatriz Branquinho Gomes
Rui António Fernandes
This study aimed to produce predictive equations to determine the optimal paddle size for young Iberian kayakers competing in three categories: U14, U16, and U18. Data were collected in Portugal and Spain between 2005 and 2018, with a sampl...
The critical role of inflammation in osteoporosis prediction unveiled by a machine learning framework integrating multi-source data [0.03%]
整合多源数据的机器学习框架揭示了炎症在骨质疏松症预测中的关键作用
Bo Liu,Hongli Chang,Peipei Li et al.
Bo Liu et al.
Objective: Osteoporosis poses a major global public health challenge. The limitations of current diagnostic methods, primarily diagnostic delays in bone density testing, are compounded by the insufficient exploration of i...