A novel anxiety-associated SNP identified in LYNX2 (LYPD1) is associated with decreased protein binding to nicotinic acetylcholine receptors [0.03%]
在LYNX2（LYPD1）中鉴定出的一种新的与焦虑相关的单核苷酸多态性与烟碱乙酰胆碱受体结合的蛋白质减少相关
Kristin R Anderson,Wenpeng Cao,Hui Sun Lee et al.
Kristin R Anderson et al.
Introduction: Anxiety disorders are among the most common mental illnesses in the US. An estimated 31.1% of U.S. adults experience any anxiety disorder at some time in their lives. Understanding some of the molecular unde...
Analysis of goal, feedback and rewards on sustained attention via machine learning [0.03%]
基于机器学习的目标、反馈和奖励对持续注意力的影响分析
Nethali Fernando,Matthew Robison,Pedro D Maia
Nethali Fernando
Introduction: Sustaining attention is a notoriously difficult task as shown in a recent experiment where reaction times (RTs) and pupillometry data were recorded from 350 subjects in a 30-min vigilance task. Subjects were...
Aldrich Chan,Philip Harvey,Rene Hernandez-Cardenache et al.
Aldrich Chan et al.
While PTSD continues to be researched in great depth, less attention has been given to the continuum of traumatic responses that resides outside this diagnosis. This investigation begins with a literature review examining the spectrum of re...
Developmental improvements in the ability to benefit from testing across middle childhood [0.03%]
从中年级到高年级测试效应量的增长
Sandra Rodríguez-Gonzalo,Jaione Arnaez-Telleria,Pedro M Paz-Alonso
Sandra Rodríguez-Gonzalo
Extensive behavioral research on adults has shown that retrieval practice is highly beneficial for long-term memory retention. However, limited evidence exists on the developmental course of this benefit. Here, we present data from a behavi...
Novel automated method to assess group dynamics reveals deficits in behavioral contagion in rats with social deficits [0.03%]
一种新颖的自动化方法可评估群体动力学并揭示行为传染在社交缺陷大鼠中的缺陷
Kirill Smirnov,Ilya Starkov,Olga Sysoeva et al.
Kirill Smirnov et al.
Behavioral copying is a key process in group actions, but it is challenging for individuals with autism spectrum disorder (ASD). We investigated behavioral contagion, or instinctual replication of behaviors, in Krushinky-Molodkina (KM) rats...
Jacob H Wilmot,Tracy L Warren,Cassiano R A F Diniz et al.
Jacob H Wilmot et al.
Molecular and genetic techniques now allow selective tagging and manipulation of the population of neurons, often referred to as "engram cells," that were active during a specific experience. One common approach to labeling these cells is t...
Selective deletion of Tsc1 from mouse cerebellar Purkinje neurons drives sex-specific behavioral impairments linked to autism [0.03%]
选择性删除小脑浦肯野神经元中的Tsc1基因驱动与自闭症相关的性别特异性行为缺陷
Ryan J Lawson,Nicholas J Lipovsek,Samuel P Brown et al.
Ryan J Lawson et al.
There is a striking sex bias in the prevalence and severity of autism spectrum disorder (ASD) with 80% of diagnoses occurring in males. Because the molecular etiology of ASD is likely combinatorial, including interactions across multiple ge...
Animacy processing by distributed and interconnected networks in the temporal cortex of monkeys [0.03%]
猴颞叶分布式互联网络处理有生命性信息机制的研究
Rizal Ichwansyah,Keigo Onda,Jun Egawa et al.
Rizal Ichwansyah et al.
Animacy perception, the ability to discern living from non-living entities, is crucial for survival and social interaction, as it includes recognizing abstract concepts such as movement, purpose, and intentions. This process involves interp...
Shifts in naturalistic behaviors induced by early social isolation stress are associated with adult binge-like eating in female rats [0.03%]
早期社会隔离应激诱发的自然行为改变与成年大鼠暴食样进食有关
Timothy B Simon,Julio Sierra,Arianna Williams et al.
Timothy B Simon et al.
Binge eating (BE) is a highly pervasive maladaptive coping strategy in response to severe early life stress such as emotional and social neglect. BE is described as repeated episodes of uncontrolled eating and is tightly linked with comorbi...
Effect of carbonated water on cerebral blood flow in the frontal region: a study using near-infrared spectroscopy [0.03%]
碳酸水对前额叶脑血流的影响——近红外光谱法研究
Wataru Kosugi,Brian Sumali,Nozomu Hamada et al.
Wataru Kosugi et al.
Introduction: Carbonated water (CarbW) affects the swallowing function associated with the action of the brainstem. In addition, CarbW ingestion promotes mean blood flow in the middle cerebral artery, which is associated ...