Proteomic insights into extinction memory deficits in stress-susceptible female rats [0.03%]
应激易感大鼠灭绝记忆缺陷的蛋白质组学研究新进展
Nashaly Irizarry-Méndez,Yelitza Acosta-Pierantoni,Alondra Diaz-Vazquez et al.
Nashaly Irizarry-Méndez et al.
Stress exposure can disrupt fear extinction, which is a hallmark of some stress-related disorders. The underlying molecular mechanisms of impaired extinction, especially in females, remain poorly understood. In this study, we investigated p...
Supportive enriched environment improves recovery from persistent motor and cognitive impairments after severe traumatic brain injury [0.03%]
支持性丰富环境可改善重度创伤性脑损伤后持续性运动和认知障碍的恢复
Margaret Anne Lovier,Michele Kyle,Karen Hughes et al.
Margaret Anne Lovier et al.
Objective: Severe traumatic brain injury (sTBI) causes permanent disability in adults worldwide. While enriched environments (EE) have been shown to improve recovery in the early post-TBI period, their efficacy during the...
Customized SAM-Med3D with multi-view adapter and T2-FLAIR mismatch features for glioma IDH genotyping and grading [0.03%]
基于多视图适配器和T2-FLAIR不匹配特征的个性化SAM-Med3D胶质瘤IDH基因分型和分级方法
Xinyu Li,Hui Li,Yunyi Hu et al.
Xinyu Li et al.
Objective: Gliomas, the most aggressive type of brain tumor, are infamous for their low survival rates. Tumor grading and isocitrate dehydrogenase (IDH) status are key prognostic biomarkers for gliomas. However, obtaining...
Guillermo Hidalgo-Gadea,Onur Güntürkün,Mehdi Behroozi
Guillermo Hidalgo-Gadea
Machine learning is revolutionizing behavioral neuroscience by enabling the study of animal behavior with greater ecological validity while maintaining experimental rigor. Traditional manual observation methods in ethology are constrained b...
Enhanced functional connectivity between the default mode network and executive control network during flow states may facilitate creativity and emotional regulation, and may improve health outcomes [0.03%]
流畅状态下默认模式网络与执行控制网络间功能连接的增强可能促进创造力和情绪调节并改善健康状况
Kelly Barnett,Fabian Vasiu
Kelly Barnett
Introduction: Flow is characterized by complete immersion and optimal engagement in a task, striking a balance between challenge and skill. Recent neuroimaging studies suggest that flow involves dynamic interactions among...
AI-enhanced adaptive testing with cognitive diagnostic feedback and its association with performance in undergraduate surgical education: a pilot study [0.03%]
基于认知诊断的自适应测试及其与本科医学生外科成绩的关系的增强型研究——一项初步研究
Nuno Silva Gonçalves,Carlos Collares,José Miguel Pêgo
Nuno Silva Gonçalves
Background: Effective feedback in the cognitive domain is essential for surgical education but often limited by resource constraints and traditional assessment formats. Artificial Intelligence (AI) has emerged as a cataly...
Novel behavioral tasks for the measurement of social motivation in mice: a comparison across strains [0.03%]
小鼠社会动机测量的新行为任务：跨品系比较
Caitlyn Wells,Kendall P Huddleston,Steven Brown et al.
Caitlyn Wells et al.
Introduction: Social isolation, reduced social interaction, and social anhedonia are associated with a range of neuropsychiatric conditions. While the search for novel pharmacological agents to treat social symptoms persi...
Traditional and non-traditional behavioral tests demonstrate the attenuation of cognitive deficits by therapeutic hypothermia in a rat model of neonatal hypoxic-ischemic encephalopathy [0.03%]
传统与非传统的行为测试表明，治疗性低体温处理可减轻新生 rats 缺氧缺血性脑病模型的认知功能障碍症状
Angela Saadat,Cortney Kaszowski,Haree Pallera et al.
Angela Saadat et al.
Introduction: Neonatal hypoxic-ischemic encephalopathy (HIE) is neurological disease caused by the deprivation of oxygen and blood flow to the brain during the developmentally-critical perinatal period. Therapeutic hypoth...
Probiotic supplementation attenuated early-life chemotherapy-induced brain development impairment in mice [0.03%]
益生菌补充减轻了早期间质化疗引起的脑发育障碍损伤
Aihua Tan,Jie Chen,Juan Zhang et al.
Aihua Tan et al.
Background: Brain dysfunction is a common post-chemotherapy sequela in acute lymphoblastic leukemia (ALL) survivors and is associated with poor academic performance and reduced work ability. The prevention of brain dysfun...
Photobiomodulation mechanisms: duration of action in the human prefrontal cortex [0.03%]
光生物调节机制：人体前额皮质的作用持续时间
Patrick O&#x;Connor,Turner Lime,Douglas W Barrett et al.
Patrick O&#x;Connor et al.
Introduction: Transcranial infrared laser stimulation (TILS) is a form of photobiomodulation (PBM) using a wavelength of 1064 nm shown to enhance metabolic and hemodynamic activity in the human prefrontal cortex (PFC). Pr...