Sex-dependent effects of food-restriction on cocaine self-administration and cocaine-seeking in rats [0.03%]
性别依赖的节食对大鼠可卡因自助和觅药的影响
Alixandria T Mascarin,Ava M Mac,Srinivasu Kallakuri et al.
Alixandria T Mascarin et al.
Introduction: Misuse of drugs and natural rewards, such as food, share common neural pathways and comparably influence behavioral consequences. Food-restriction enhances drug-taking and drug-seeking behaviors in animals, ...
Vagus nerve stimulation ameliorates cognitive impairment caused by hypoxia [0.03%]
迷走神经刺激改善缺氧引起的学习记忆障碍
Birendra Sharma,Krysten A Jones,Laura K Olsen et al.
Birendra Sharma et al.
Introduction: Hypoxia significantly impairs cognitive function due to the brain's high demand for oxygen. While emerging evidence suggests that vagus nerve stimulation (VNS) can enhance cognition, its effectiveness in mit...
Characterization of alterations in spontaneous behaviors in a rat model of neuropathic pain - new outcome measures for pain evaluation? [0.03%]
大鼠神经病理性疼痛模型中自发行为改变的特征-新的疼痛评估结果指标？
Annamária Liptáková,M J Castelhano-Carlos,Juliana Fiúza-Fernandes et al.
Annamária Liptáková et al.
Chronic pain affects all life domains including social interaction and responding. The aim of this study was to track spontaneous behaviors in an experimental chronic pain model to uncover alternative pain indicators in a socially and physi...
Constitutive activity of the inhibitory G protein pathway mediated by non-visual opsin Opn7b reduces cFos activity in stress and fear circuits and modulates avoidance behavior [0.03%]
由非视觉视蛋白Opn7b介导的抑制性G蛋白通路的组成型活性通过减少压力和恐惧环路中的cFos活性来调节回避行为
Hanna Böke,Hannah Schulte,Maria Worm et al.
Hanna Böke et al.
Constitutive activity of G protein-coupled receptors (GPCRs) plays an important role in brain function and disease including neurodegenerative and psychiatric disorders. The non-visual opsin Opn7b is a constitutively active G i/o coupled GP...
Vitamin A attenuates PFOS-induced neurotoxicity and alters early proximity patterns to conspecifics in zebrafish larvae [0.03%]
维生素A可减轻全氟辛烷磺酸对斑马鱼幼体神经毒性和社交行为的影响
Peiyun Jiang,Jingyu Wang,Xiaoying Wang et al.
Peiyun Jiang et al.
Introduction: Perfluorooctane sulfonic acid (PFOS), a persistent perfluoroalkyl substance with ubiquitous environmental distribution and bioaccumulative potential, has raised significant public health concerns due to its ...
Effects of propofol on the cognition and hippocampal N-methyl-D-aspartate subunits expression in an MPTP-induced Parkinson's disease rat model [0.03%]
异丙酚对莫凡梯帕诱导的帕金森病大鼠认知及海马N-甲基-D-天冬氨酸受体亚单位表达的影响
Ping Zhu,Yongyan Zhang,Hua Xu et al.
Ping Zhu et al.
Introduction: Parkinson's disease (PD) is associated with higher risk of cognitive impairment. Until now, little is known about the effect of anesthetics on cognitive function in PD patients. The imbalance of hippocampal ...
Higher levels of D2R and D3R in the frontal-striatal regions are associated with reduced perseverative reward seeking after opioid abstinence [0.03%]
较高的D2R和D3R额皮层-纹状体通路水平与阿片类药物脱毒后的持续性觅药行为降低有关
Yingying Li,Xigeng Zheng,Cong Gao et al.
Yingying Li et al.
Introduction: The lower levels of dopamine D2 receptor (D2R) in the striatum and the heightened levels of dopamine D2 receptor (D3R) in the midbrain have been linked to impulsive behavior and risky decision-making associa...
Yung-Hsun Cheng
Yung-Hsun Cheng
Background study: The rapid growth of online gaming has sparked interest in its potential effects on cognitive abilities such as creativity. Previous research indicates that interactive digital environments may enhance cr...
Deletion of Mex3c gene leads to autistic-like behavior in mice by inhibiting AMPK signal pathway [0.03%]
Mex3c基因缺失通过抑制AMPK信号通路导致小鼠自闭症样行为
Hui Cai,Chengping Zhang,Haonan Zhang et al.
Hui Cai et al.
Introduction: Autism Spectrum Disorder (ASD) is a hereditary neurodevelopmental condition influenced by genetic alterations, particularly in genes regulating neural development and synaptic plasticity. Emerging evidence s...
Sex differences in anxiety and depression: insights from adult rodent models of chronic stress and neural plasticity [0.03%]
慢性压力和神经可塑性成人鼠模型对焦虑及抑郁性别差异研究的新见解
Rachel Bowman,Maya Frankfurt,Victoria Luine
Rachel Bowman
The often co-morbid conditions of depression and anxiety are the most common mental illnesses and are more prevalent among females than males. Chronic stress paradigms in rodents serve as valuable preclinical models for investigating the fa...