Histone lactylation-mediated glycolysis-ferroptosis axis in neurological diseases [0.03%]
组蛋白乳酰化介导的神经疾病中的糖酵解-铁死亡轴
Zengrong Wei,Lu Bai,Xueting Liu et al.
Zengrong Wei et al.
Histone lactylation is an emerging epigenetic modification that covalently links the glycolytic metabolite lactate to histones, thereby establishing a direct link between cellular metabolic status and gene transcription programs. Recent stu...
Prenatal and neonatal housing conditions affect anxiety-like behavior in adulthood in rats and interact with brain-derived neurotrophic factor (BDNF) Val66Met to alter expression of BDNF and stress markers in the ventral hippocampus [0.03%]
妊娠和新生儿期的饲养条件会影响大鼠成年后的类似焦虑的行为并与脑源性神经营养因子（BDNF）Val66Met相互作用以改变腹侧海马区BDNF和压力标志物的表达
Maarten van den Buuse,Michelle Corrone,Emily J Jaehne et al.
Maarten van den Buuse et al.
Introduction: We investigated the interaction of the brain-derived neurotrophic factor (BDNF) gene variant, Val66Met, with the effect of prenatal/neonatal environmental conditions on anxiety-like behavior in adulthood in ...
BDNF-amyloid- β Axis in Alzheimer's disease: molecular mechanisms and therapeutic perspectives [0.03%]
阿尔茨海默病中的脑源性神经营养因子-β淀粉样蛋白轴：分子机制和治疗前景
Fangfang Liu,Yuanmao Huang,Aiping Wang et al.
Fangfang Liu et al.
Alzheimer's disease (AD), the most common cause of dementia in older adults, is characterized by progressive cognitive decline, synaptic dysfunction, and neuronal loss. Among the multifactorial mechanisms implicated in AD, reciprocal intera...
16p11.2 microdeletion enhances gene expression variability between human IPSC-derived forebrain interneuron progenitor cells in culture [0.03%]
16P11.2基因缺失增强人类诱导多能干细胞来源的前脑中间神经元祖细胞培养中的基因表达变异
Yifei Yang,Idoia Quintana Urzainqui,Thomas Pratt
Yifei Yang
The 574-kilobase pair 16p11.2 microdeletion raises a person's odds for neurodevelopmental and energy balance conditions, particularly autism and obesity, with considerable clinical heterogeneity, and how much this reflects genetic versus en...
CircHomer1 may contribute to postoperative cognitive impairment by modulating Homer1b/mGluR5-associated signaling in the vCA1 region of aged mice [0.03%]
Circular RNA CircHomer1 可通过调节老年小鼠海马内嗅皮质回路 CA1 区域 Homer1b/mGluR5 信号通路参与术后认知功能障碍病理进程的研究
Wei Ran,Yiwei Shen,Ruixue Yuan et al.
Wei Ran et al.
Background: Postoperative delirium (POD) is a common and severe complication in elderly patients after surgery, primarily characterized by a decline in cognitive function. ...
Correction: Chloral hydrate alters brain activation induced by methamphetamine-associated cue and prevents relapse [0.03%]
纠正：氯醛hydrate改变甲基苯丙胺相关线索诱导的脑激活并预防复吸
Chenyu Jiang,Yunlong Xu,Jiafeng Zhong et al.
Chenyu Jiang et al.
[This corrects the article DOI: 10.3389/fnmol.2022.934167.]. Keywords: addiction; brain activation; chloral ...
Published Erratum
Frontiers in molecular neuroscience. 2026 Jun 24:19:1895561. DOI:10.3389/fnmol.2026.1895561 2026
Transcriptomic signatures of the insular cortex in a mouse model of neuropathic pain [0.03%]
神经病理性疼痛小鼠模型中岛皮层的转录组标志物
Yang Bai,Guo-Quan Yao,Cheng-Guo Jiang et al.
Yang Bai et al.
Background: Neuropathic pain (NP) remains poorly managed by current therapies. Although the insular cortex (IC) is critical for cortical pain processing, a comprehensive spatiotemporal molecular characterization of the IC...
Modulation of the microbiota-lipid-brain axis by modified Chaihu-Longgu-Muli Decoction ameliorates chronic stress-induced depression [0.03%]
调肝汤加减通过调控菌脂脑轴改善慢性应激抑郁状态
Yonghao Chen,Yongcheng Liu,Ruxi Tong et al.
Yonghao Chen et al.
Background and aims: Modified Chaihu-Longgu-Muli Decoction (mCLMD) has well-established clinical antidepressant efficacy, yet its precise systemic mechanisms of action remain incompletely characterized. Here, we employed ...
Tuina therapy alleviates neuropathic pain by modulating the CX3CL1/CX3CR1 axis to inhibit degradation of the perineuronal nets [0.03%]
推拿通过调节CX3CL1/CX3CR1轴抑制神经网退化来缓解神经病理性疼痛作用机制研究
Yukui Tian,Cheng Wang,Qingguang Zhu et al.
Yukui Tian et al.
Introduction: Tuina, a traditional Chinese non-pharmacological therapy, is effective in treating neuropathic pain (NP). However, its underlying molecular mechanisms remain elusive. The degradation of perineuronal nets (PN...
Piezo1 in neuropathic pain: a putative mechanotransduction hub and underlying mechanisms [0.03%]
Piezo1在神经病理性疼痛中的作用：一个假定的机械转导中心及其潜在机制
Kuangpin Liu,Chunyan Li,Wei Ma et al.
Kuangpin Liu et al.
Neuropathic pain (NP) is a chronic pain syndrome caused by damage or dysfunction in the nervous system. Its pathogenesis involves enhanced neuronal excitability, inflammatory responses, and neuron-glial interactions. Mechanotransduction, a ...