Co-expression of Argonaute2 Enhances Short Hairpin RNA-induced RNA Interference in Xenopus CNS Neurons In Vivo [0.03%]
Ago2共表达增强shrna在非洲爪蟾中枢神经元中的rnai效应
Chih-Ming Chen,Shu-Ling Chiu,Wanhua Shen et al.
Chih-Ming Chen et al.
RNA interference (RNAi) is an evolutionarily conserved mechanism for sequence-specific gene silencing. Recent advances in our understanding of RNAi machinery make it possible to reduce protein expression by introducing short hairpin RNA (sh...
Offline Identification of Imagined Speed of Wrist Movements in Paralyzed ALS Patients from Single-Trial EEG [0.03%]
来自单次试验EEG的瘫痪ALS患者的想象性手腕运动速度的离线识别
Ying Gu,Dario Farina,Ander Ramos Murguialday et al.
Ying Gu et al.
The study investigated the possibility of identifying the speed of an imagined movement from EEG recordings in amyotrophic lateral sclerosis (ALS) patients. EEG signals were acquired from four ALS patients during imagination of wrist extens...
A Simple and Accurate onset Detection Method for a Measured Bell-shaped Speed Profile [0.03%]
一种简单的检测测度钟形速度剖面的时域起始点的方法
Lior Botzer,Amir Karniel
Lior Botzer
Motor control neuroscientists measure limb trajectories and extract the onset of the movement for a variety of purposes. Such trajectories are often aligned relative to the onset of individual movement before the features of that movement a...
P300-Based Brain-Computer Interface Communication: Evaluation and Follow-up in Amyotrophic Lateral Sclerosis [0.03%]
基于P300的脑计算机接口交流：在肌萎缩侧索硬化中的评估和随访研究
Stefano Silvoni,Chiara Volpato,Marianna Cavinato et al.
Stefano Silvoni et al.
To describe results of training and 1-year follow-up of brain-communication in a larger group of early and middle stage amyotrophic lateral sclerosis (ALS) patients using a P300-based brain-computer interface (BCI), and to investigate the r...
Lei Chen,Qiao-Ling Cui,Wing-Ho Yung
Lei Chen
The undecapeptide substance P has been demonstrated to modulate neuronal activity in a number of brain regions by acting on neurokinin-1 receptors. Anatomical studies revealed a moderate level of neurokinin-1 receptor in rat globus pallidus...
Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource [0.03%]
小鼠海马转录组的遗传学：系统研究及在线神经基因组资源
Rupert W Overall,Gerd Kempermann,Jeremy Peirce et al.
Rupert W Overall et al.
Differences in gene expression in the CNS influence behavior and disease susceptibility. To systematically explore the role of normal variation in expression on hippocampal structure and function, we generated an online microarray database ...
To What Extent is Blood a Reasonable Surrogate for Brain in Gene Expression Studies: Estimation from Mouse Hippocampus and Spleen [0.03%]
血液在基因表达研究中能在多大程度上作为大脑的合理替代品：来自小鼠海马和脾脏的估计
Matthew N Davies,Sarah Lawn,Steven Whatley et al.
Matthew N Davies et al.
Microarrays are designed to measure genome-wide differences in gene expression. In cases where a tissue is not accessible for analysis (e.g. human brain), it is of interest to determine whether a second, accessible tissue could be used as a...
Meta-analysis of kindling-induced gene expression changes in the rat hippocampus [0.03%]
大鼠海马痫灶发生过程中基因表达变化的meta分析研究
Sanja Rogic,Paul Pavlidis
Sanja Rogic
Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies. Because this con...
Wiring Olfaction: The Cellular and Molecular Mechanisms that Guide the Development of Synaptic Connections from the Nose to the Cortex [0.03%]
嗅觉的神经连接机制：从鼻子到大脑皮层的突触连接的细胞和分子指南
Fernando de Castro
Fernando de Castro
Within the central nervous system, the olfactory system fascinates by its developmental and physiological particularities, and is one of the most studied models to understand the mechanisms underlying the guidance of growing axons to their ...
Ablation of mouse adult neurogenesis alters olfactory bulb structure and olfactory fear conditioning [0.03%]
小鼠成体神经发生的选择性消融改变了嗅球的结构及其在嗅觉恐惧条件反射中的作用
Matthew T Valley,Tanner R Mullen,Lucy C Schultz et al.
Matthew T Valley et al.
Adult neurogenesis replenishes olfactory bulb (OB) interneurons throughout the life of most mammals, yet during this constant flux it remains unclear how the OB maintains a constant structure and function. In the mouse OB, we investigated t...