Mapping primary gyrogenesis during fetal development in primate brains: high-resolution in utero structural MRI of fetal brain development in pregnant baboons [0.03%]
恒河猴妊娠期间胎儿脑发育的高分辨率宫内结构MRI:灵长类胚胎大脑初级皮层发生的过程测绘
Peter Kochunov,Carlos Castro,Duff Davis et al.
Peter Kochunov et al.
The global and regional changes in the fetal cerebral cortex in primates were mapped during primary gyrification (PG; weeks 17-25 of 26 weeks total gestation). Studying pregnant baboons using high-resolution MRI in utero, measurements inclu...
Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand? [0.03%]
运动神经元疾病中神经营养因子治疗的研究进展及展望
Alexandre Henriques,Claudia Pitzer,Armin Schneider
Alexandre Henriques
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within 3-5 years after disease onset. Therapeutic options remain limited despite substa...
Invariance in visual object recognition requires training: a computational argument [0.03%]
视觉物体识别中的不变性需要训练:一个计算理由
Robbe L T Goris,Hans P Op de Beeck
Robbe L T Goris
Visual object recognition is remarkably accurate and robust, yet its neurophysiological underpinnings are poorly understood. Single cells in brain regions thought to underlie object recognition code for many stimulus aspects, which poses a ...
Characterization of neural activity recorded from the descending tracts of the rat spinal cord [0.03%]
大鼠脊髓下行传导束记录到的神经活动特征分析
Abhishek Prasad,Mesut Sahin
Abhishek Prasad
A multi-electrode array (MEA) was implanted in the dorsolateral funiculus of the cervical spinal cord to record descending information during behavior in freely moving rats. Neural signals were characterized in terms of frequency and inform...
Nitric oxide enhances inhibitory synaptic transmission and neuronal excitability in Guinea-pig submucous plexus [0.03%]
一氧化氮增强象牙猪粘膜下plexus的抑制性突触传递和神经元兴奋性
Joel C Bornstein,Kathryn A Marks,Jaime Pei Pei Foong et al.
Joel C Bornstein et al.
Varicosities immunoreactive for nitric oxide synthase (NOS) make synaptic connections with submucosal neurons in the guinea-pig small intestine, but the effects of nitric oxide (NO) on these neurons are unknown. We used intracellular record...
Charles C Lee,S Murray Sherman
Charles C Lee
The classic view of auditory information flow depicts a simple serial route from the periphery through tonotopically-organized nuclei in the brainstem, midbrain and thalamus, ascending eventually to the neocortex. Yet, complicating this pic...
Ferdinando A Mussa-Ivaldi,Simon T Alford,Michela Chiappalone et al.
Ferdinando A Mussa-Ivaldi et al.
Brain-machine interfaces (BMIs) are mostly investigated as a means to provide paralyzed people with new communication channels with the external world. However, the communication between brain and artificial devices also offers a unique opp...
Laurent Gautron,Sophie Layé
Laurent Gautron
Compelling data demonstrate that inflammation-associated anorexia directly results from the action of pro-inflammatory factors, primarily cytokines and prostaglandins E2, on the nervous system. For instance, the aforementioned pro-inflammat...
In Silico Enhanced Restriction Enzyme Based Methylation Analysis of the Human Glioblastoma Genome Using Agilent 244K CpG Island Microarrays [0.03%]
人胶质母细胞瘤基因组的甲基化分析(使用Agilent 244K CpG岛微阵列进行基于限制性内切酶的体内增强分析)
Anh Tran,Cameron Escovedo,Justine Migdall-Wilson et al.
Anh Tran et al.
Genome wide methylation profiling of gliomas is likely to provide important clues to improving treatment outcomes. Restriction enzyme based approaches have been widely utilized for methylation profiling of cancer genomes and will continue t...
Frequency-Domain Analysis of Intrinsic Neuronal Properties using High-Resistant Electrodes [0.03%]
基于高阻抗电极的固有神经元特性频域分析方法研究
Christian Rössert,Hans Straka,Stefan Glasauer et al.
Christian Rössert et al.
Intrinsic cellular properties of neurons in culture or slices are usually studied by the whole cell clamp method using low-resistant patch pipettes. These electrodes allow detailed analyses with standard electrophysiological methods such as...