Change of epigenetic control of cystathionine beta-synthase gene expression through dietary vitamin B12 is not recovered by methionine supplementation [0.03%]
膳食维生素B12引起的半胱氨酸β-合成酶基因表观遗传调控改变不能通过甲硫氨酸补充得到恢复
Atsushi Uekawa,Keishuke Katsushima,Asumi Ogata et al.
Atsushi Uekawa et al.
Background/aims: Vitamin B12 (B-12) is an essential cofactor for methionine synthase, and methionine is critical for the methylation of various biological molecules including DNA. Whether changes in B-12 levels can alter ...
Genome-wide analysis of dietary eicosapentaenoic acid- and oleic acid-induced modulation of colon inflammation in interleukin-10 gene-deficient mice [0.03%]
基因分析_IL-10基因缺陷小鼠饮食二十碳五烯酸和油酸诱导的结肠炎的影响研究
Bianca Knoch,Matthew P G Barnett,Shuotun Zhu et al.
Bianca Knoch et al.
Background/aims: Dietary n-3 polyunsaturated fatty acids can reduce inflammation via a range of mechanisms. This study tested the effect of dietary eicosapentaenoic acid (EPA) on intestinal inflammation using interleukin-...
Folate nutritional genetics and risk for hypertension in an elderly population sample [0.03%]
叶酸营养基因组学与老年人群高血压患病风险的关系研究
Xiaowei Ng,Lyndell Boyd,Lisa Dufficy et al.
Xiaowei Ng et al.
Background/aims: 118 elderly participants (65-90 years) were assessed for any relationship between folate, related genes and hypertension. Methods: ...
Influence of CYP11B2 gene polymorphism on the prevalence of hypertension and the blood pressure in Japanese men: interaction with dietary salt intake [0.03%]
日本男性中CYP11B2基因多态性对高血压患病率及血压水平的影响及其与食盐摄入量的交互作用
Yixuan Song,Koichi Miyaki,Jungo Araki et al.
Yixuan Song et al.
Aims: CYP11B2 gene encodes a key enzyme for the production of aldosterone. Our aim is to investigate the association of -344T/C polymorphism with hypertension in Japanese men. The interaction between genotypes and dietary...
Effect of dietary calcium and dairy proteins on the adipose tissue gene expression profile in diet-induced obesity [0.03%]
膳食钙和乳清蛋白对饮食诱导的肥胖小鼠脂肪组织基因表达的影响
Taru K Pilvi,Markus Storvik,Marjut Louhelainen et al.
Taru K Pilvi et al.
Background/aims: Calcium and dairy proteins have been postulated to explain why the intake of dairy products correlates inversely with body mass index in several populations. We have shown that a high-calcium diet with wh...
Public health genomics and genetic test evaluation: the challenge of conducting behavioural research on the utility of lifestyle-genetic tests [0.03%]
公共卫生基因组学和基因检测评估：开展生活方式-基因检测实用性的行为研究面临的挑战
Saskia C Sanderson,Jane Wardle,Steve E Humphries
Saskia C Sanderson
Human genetics research is increasingly concerned with multifactorial conditions such as diabetes and heart disease, which are influenced not only by genetic but also lifestyle factors such as diet and smoking. Although the results of 'life...
Genetic polymorphisms of tumor necrosis factor-alpha modify the association between dietary polyunsaturated fatty acids and plasma high-density lipoprotein-cholesterol concentrations in a population of young adults [0.03%]
肿瘤坏死因子α的基因多态性修饰饮食中的必需脂肪酸与血浆高密度脂蛋白胆固醇浓度之间的关系
Bénédicte Fontaine-Bisson,Ahmed El-Sohemy
Bénédicte Fontaine-Bisson
Background/aims: Genetic polymorphisms in tumor necrosis factor-alpha (TNF-alpha) modify the association between polyunsaturated fatty acids (PUFA) and plasma high-density lipoprotein (HDL) cholesterol in a population wit...
E C M Mariman
E C M Mariman
Epigenetic phenomena are changes in phenotype that are due to resetting of gene expression under the influence of the environment or genetic factors without changing the DNA sequence. Usually this resetting occurs at a certain stage in life...
Effect of the PPAR-Alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 polyunsaturated fatty acids [0.03%]
PPAR-Alpha L162V多态性对n-3多不饱和脂肪酸反应性心血管疾病风险因素的影响
Dominique Caron-Dorval,Pascale Paquet,Ann-Marie Paradis et al.
Dominique Caron-Dorval et al.
Background: Dietary n-3 polyunsaturated fatty acids (PUFAs) decrease the risk of cardiovascular disease (CVD). Yet, genetic variations of the gene encoding the peroxisome proliferator-activated receptor-alpha (PPARalpha) ...