Effect of Water Bath versus Refrigerator Thaw on Cryoprecipitate Fibrinogen and Factor VIII Content Using a Pre-Pooled Plasma Experimental Approach [0.03%]
采用预先汇集血浆的实验方法研究水浴解冻和冰箱解冻对 cryoprecipitate 的纤维蛋白原及因子 VIII 含量的影响
Jessie A Swanson,Michelle A Soland,Scott A Hammel et al.
Jessie A Swanson et al.
Introduction: Originally developed as a form of factor VIII concentrate, cryoprecipitate's primary clinical use has changed to treat fibrinogen deficiency as highlighted by recent approval of pathogen-reduced cryoprecipit...
Influence of the Immune Checkpoint Inhibitors on the Hemostatic Potential of Blood Plasma [0.03%]
免疫检查点抑制剂对血浆凝血潜能的影响
Irina Patalakh,Alexandra Wandersee,Julian Schlüter et al.
Irina Patalakh et al.
Introduction: Immune checkpoint inhibitors (ICIs) have revolutionized classical treatment approaches of various cancer entities, but are also associated with a number of side effects. One of these may be life-threatening ...
[This corrects the article DOI: 10.1159/000532049.]. Copyright © 2024 by The Author(s) Published by S. Karger AG, Basel.
Virus-Specific T-Cell Therapy for the Management of Viral Infections in the Immunocompromised [0.03%]
免疫缺陷患者病毒性感染的T细胞治疗管理疗法
Kiriakos Koukoulias,Penelope Georgia Papayanni,Ann Marie Leen et al.
Kiriakos Koukoulias et al.
Background: Immunocompromised individuals are at major risk for severe infectious complications. This is particularly relevant in the context of allogeneic hematopoietic stem cell transplantation (allo-HCT) - a treatment ...
Empowering Natural Killer Cells to Combat Acute Myeloid Leukemia: Perspective on CAR-NK Cell Therapy [0.03%]
赋能自然杀伤细胞对抗急性髓系白血病：嵌合抗原受体自然杀伤细胞治疗的展望
Fenja Gierschek,Juliane Schlueter,Ines Kühnel et al.
Fenja Gierschek et al.
Background: Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with a high relapse rate and still limited therapeutic options. Natural killer (NK) cell-based immunotherapy has the potential to improve ou...
Cytokine-Induced Killer Cells: A Unique Platform for Adoptive Cell Immunotherapy after Allogeneic Hematopoietic Stem Cell Transplantation [0.03%]
细胞因子诱导的杀伤细胞：allo-HSCT后过继性细胞免疫治疗的理想平台
Eva Rettinger
Eva Rettinger
Background: Immunotherapies in general, and cellular immunotherapies, in particular are becoming increasingly integrated into current personalized cancer treatment, though still facing some obstacles in the allogeneic hem...
Adoptive Cell Therapy from the Dish: Potentiating Induced Pluripotent Stem Cells [0.03%]
从培养皿中获得的过继性细胞疗法：诱导多能干细胞的应用与前景
Pieter L Lindenbergh,Sjoukje J C van der Stegen
Pieter L Lindenbergh
Background: The clinical success of autologous adoptive cell therapy (ACT) is substantial but wide application is challenged by the quality and quantity of the patient's immune cells and the need for personalized manufact...
Britta Eiz-Vesper,Halvard Bonig
Britta Eiz-Vesper
Lara Sophie Schlegel,Patrick Schlegel
Lara Sophie Schlegel
Background: Cellular therapies leveraging genetically engineered immune effector cells have witnessed a remarkable surge in success, particularly evident in the notable high rates of remission induction and durable remiss...
Purified Granulocyte Concentrates from Buffy Coats with Extended Storage Time [0.03%]
延长保存时间的 buffy coat 中纯化的粒细胞浓缩物
Gerd Klinkmann,Fanny Doss,Sandra Doss et al.
Gerd Klinkmann et al.
Background: Granulocyte concentrates (GCs) are usually prepared by single-donor apheresis after G-CSF pretreatment and have to be transfused within 24 h after cell collection because of the rapid decrease in pH and cell s...