Classical Haematology: Dynamic Development at the Interface of Transfusion Medicine and Haematology [0.03%]
经典血液学：输血医学与血液学界面的动态发展
Hubert Schrezenmeier
Hubert Schrezenmeier
Paroxysmal Nocturnal Hemoglobinuria, Pathophysiology, Diagnostics, and Treatment [0.03%]
阵发性夜间血红蛋白尿的发病机制、诊断和治疗
Jens Peter Panse,Britta Höchsmann,Jörg Schubert
Jens Peter Panse
Background: Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by intravascular hemolysis (IVH) due to diminished or absent inhibition of the complement system because of deficient expression of cell-anchored comp...
Wilma Barcellini,Bruno Fattizzo
Wilma Barcellini
Background: Autoimmune hemolytic anemia (AIHA) is a rare disease due to increased destruction of erythrocytes by autoantibodies, with or without complement activation. ...
Sickle Cell Disease [0.03%]
镰状细胞疾病
Joachim B Kunz,Laura Tagliaferri
Joachim B Kunz
Background: Sickle cell disease (SCD) is among the most frequent hereditary disorders globally and its prevalence in Europe is increasing due to migration movements. ...
Regulation of the Lewis Blood Group Antigen Expression: A Literature Review Supplemented with Computational Analysis [0.03%]
露易斯血型抗原表达调控的文献回顾及计算分析补充
Martin Wipplinger,Sylvia Mink,Maike Bublitz et al.
Martin Wipplinger et al.
Background: The Lewis (Le) blood group system, unlike most other blood groups, is not defined by antigens produced internally to the erythrocytes and their precursors but rather by glycan antigens adsorbed on to the eryth...
Review of ABO Expression and Variations based on Transcriptional Regulation of the ABO Blood Group Gene [0.03%]
基于ABO血型基因转录调控的ABO表达及变异研究进展综述
Kenichi Ogasawara,Rie Sano,Yoshihiko Kominato
Kenichi Ogasawara
Background and summary: We review the transcriptional regulation of ABO expression and discuss variants in the promoter and erythroid cell-specific regulatory region in individuals with weak ABO phenotypes such as Bm, Am,...
Regulation of Blood Group Expression: Another Layer of Complexity to Consider [0.03%]
血型表达的调节：需要考虑的复杂性另一层
Christoph Gassner,Martin L Olsson
Christoph Gassner
In vitro Evaluation of DINCH-Plasticized Blood Bags for Red Blood Cell Storage with CPDA-1 Anticoagulant [0.03%]
DINCH增塑的血液储存袋贮存红细胞（CPDA-1抗凝剂）的体外评价研究
Hyungsuk Kim,Kyunghoon Lee,Soo Hyun Seo et al.
Hyungsuk Kim et al.
Introduction: Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer commonly used in blood bags. Despite its protective effects on red blood cell (RBC) storage, concerns about its reproductive toxicity exist. This study inve...
Romy Kronstein-Wiedemann,Stephan R Künzel,Jessica Thiel et al.
Romy Kronstein-Wiedemann et al.
Background: MicroRNAs (miRNAs) are small, endogenous non-coding RNA molecules that inhibit gene expression through either destabilization of the target mRNA or translational repression. MiRNAs recognize target sites, most...
CRISPR/Cas9-Editing K562 Cell Line as a Potential Tool in Transfusion Applications: Knockout of Vel Antigen Gene [0.03%]
基于CRISPR/Cas9基因编辑技术的K562细胞系在输血医学Vel抗原敲除中的应用研究
Jiaxuan Yang,Aijing Li,Minghao Li et al.
Jiaxuan Yang et al.
Introduction: The Vel- phenotype is a rare blood group, and it is challenging for identifying this phenotype due to limited available reagents. Moreover, there are relatively few studies on genomic editing of erythroid an...