Empowering Natural Killer Cells to Combat Acute Myeloid Leukemia: Perspective on CAR-NK Cell Therapy [0.03%]
赋能自然杀伤细胞对抗急性髓系白血病：嵌合抗原受体自然杀伤细胞治疗的展望
Fenja Gierschek,Juliane Schlueter,Ines Kühnel et al.
Fenja Gierschek et al.
Background: Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with a high relapse rate and still limited therapeutic options. Natural killer (NK) cell-based immunotherapy has the potential to improve ou...
Cytokine-Induced Killer Cells: A Unique Platform for Adoptive Cell Immunotherapy after Allogeneic Hematopoietic Stem Cell Transplantation [0.03%]
细胞因子诱导的杀伤细胞：allo-HSCT后过继性细胞免疫治疗的理想平台
Eva Rettinger
Eva Rettinger
Background: Immunotherapies in general, and cellular immunotherapies, in particular are becoming increasingly integrated into current personalized cancer treatment, though still facing some obstacles in the allogeneic hem...
Adoptive Cell Therapy from the Dish: Potentiating Induced Pluripotent Stem Cells [0.03%]
从培养皿中获得的过继性细胞疗法：诱导多能干细胞的应用与前景
Pieter L Lindenbergh,Sjoukje J C van der Stegen
Pieter L Lindenbergh
Background: The clinical success of autologous adoptive cell therapy (ACT) is substantial but wide application is challenged by the quality and quantity of the patient's immune cells and the need for personalized manufact...
Britta Eiz-Vesper,Halvard Bonig
Britta Eiz-Vesper
Lara Sophie Schlegel,Patrick Schlegel
Lara Sophie Schlegel
Background: Cellular therapies leveraging genetically engineered immune effector cells have witnessed a remarkable surge in success, particularly evident in the notable high rates of remission induction and durable remiss...
Purified Granulocyte Concentrates from Buffy Coats with Extended Storage Time [0.03%]
延长保存时间的 buffy coat 中纯化的粒细胞浓缩物
Gerd Klinkmann,Fanny Doss,Sandra Doss et al.
Gerd Klinkmann et al.
Background: Granulocyte concentrates (GCs) are usually prepared by single-donor apheresis after G-CSF pretreatment and have to be transfused within 24 h after cell collection because of the rapid decrease in pH and cell s...
Platelet Additive Solutions SSP+ and T-PAS+ Are Interchangeable for Platelet Concentrate Storage despite Differences in Composition and Plasticizer [0.03%]
尽管血小板添加溶液SSP+和T-PAS+在成分和增塑剂方面存在差异，但它们可用于储存浓缩血小板
Britt Van Aelst,Karen Bens,Bea Sabot et al.
Britt Van Aelst et al.
Introduction: Platelet additive solutions support ex vivo storage of platelet concentrates used for transfusion. The composition of platelet additive solutions within one generation (i.e., PAS-E) is similar but not identi...
Erythrocyte Alloimmunization and Autoimmunization in the Pediatric Population: A Multicenter, Cross-Sectional Study in Central China [0.03%]
中国中部地区儿科人群红细胞同种免疫和自身免疫的多中心横断面研究
Yongjun Wang,Yuanqing Yang,Zhengfeng Li et al.
Yongjun Wang et al.
Background: Erythrocyte alloantibodies and autoantibodies complicate transfusion. However, the prevalence of erythrocyte alloimmunization and autoimmunization has not been estimated in the Chinese pediatric population. Th...
The Application of Regional Citrate Anticoagulation in Protein A Immunoadsorption: A Single-Center Retrospective Cohort Study [0.03%]
区域枸橼酸抗凝在蛋白A免疫吸附中的应用：一项单中心回顾性队列研究
Amir Muhammad,Xueling Hu,Juan Pan et al.
Amir Muhammad et al.
Introduction: Protein A immunoadsorption (IA) is proving to be an effective treatment method for autoimmune diseases and other disorders. Regional citrate anticoagulation (RCA) prevents clotting in extracorporeal circuits...
Impact of Shelf-Life Extension on Platelet Availability: Results from an Inventory Management Modeling Study [0.03%]
贮存期延长对血小板供应的影响——基于库存模拟的研究结果
Veronika Brixner,Marcia Cardoso,Erik Spaepen et al.
Veronika Brixner et al.
Introduction: In Germany, demand for platelet transfusion is maintained or even increasing, despite a decrease in whole blood donations observed in the last decade. The shelf-life of platelet concentrates (PCs) in Germany...