The Novel Variant c.122delG on the ABO*B3.0x Allele Associated with B3 Phenotype [0.03%]
ABO*B3.0x等位基因上的新突变c.122delG与B3表型相关性研究
Yu Zhang,Yating Ling,Meng Li et al.
Yu Zhang et al.
Introduction: B3 is known to be one of the B subtypes that are characterized by serologic mixed-field agglutination. The proportion of Chinese Han individuals with the B3 subtype (B type) and AB3 subtype (AB type) is abou...
Microangiopathic Anemia [0.03%]
微血管性贫血
Martin Bommer,Johannes Bloehdorn
Martin Bommer
Background: Patients suffering from hemolytic anemia, thrombocytopenia, and organ damage may suffer from microangiopathic anemia, also called thrombotic microangiopathy (TMA). This condition is caused by many different pa...
Yan Wang,Lvling Zhang,Na Ma et al.
Yan Wang et al.
Background: Platelet transfusion is essential for preventing and treating hemorrhage in oncology patients and can markedly improve quality of life and survival. However, access to platelet concentrates is often limited by...
Irradiation with 265-nm Ultraviolet Light-Emitting Diodes to Plasma: Alterations of Hemostatic Parameters and von Willebrand Factor [0.03%]
265nm紫外光发光二极管照射对血浆凝血指标及血管性假血友病因子的影响
Tomoya Hayashi,Yoshihiro Fujimura,Yoshihiko Sakurai et al.
Tomoya Hayashi et al.
Introduction: Among pathogen inactivation methods for blood products, an ultraviolet C (UVC) irradiation has been attracting attention. We previously reported that 265 nm UV-LED (UVC-LED) effectively prevents bacterial in...
Genotype Distribution and Clinical Characteristics of Thalassemia Patients Needing Transfusion in Yangjiang, Western Guangdong [0.03%]
广东省阳江地区输血性地中海贫血患者的基因型分布及临床特征
Zhi-Xiao Chen,Rong-Huo Liu,Jian-Cheng Huang et al.
Zhi-Xiao Chen et al.
Objectives: This study aimed to evaluate the distribution of genotypes and iron metabolism imbalance in transfusion-dependent thalassemia patients. Method...
Single-Tube Multiplex PCR-SSP for the Detection of RHD Variant Alleles Commonly Found in Serologically D- Phenotype Individuals in a Thai Population [0.03%]
应用于泰国D血型人群RhD阴性表型个体的RHD变异等位基因检测的多重PCR-SSP单管法
Ornuma Pittayabumrung,Chanvit Leelayuwat,Amornrat V Romphruk et al.
Ornuma Pittayabumrung et al.
Introduction: The molecular basis of the RHD gene found in serologically D- phenotype individuals differs with race/ethnicity. Therefore, we aimed to develop a single-tube multiplex PCR-sequence specific primer (multiplex...
CLIC1 Supports Mechanisms Related to Platelet Activation and Thrombosis [0.03%]
CLIC1支持与血小板活化和血栓形成相关的机制
Lynn M Knowles,Emmanuel Ampofo,Michael D Menger et al.
Lynn M Knowles et al.
Background: Chloride intracellular channel 1 (CLIC1) is expressed in endothelial cells and platelets. Loss-of-function studies suggest that CLIC1 is involved in adhesive interactions in either cell type, but the exact mec...
Unbiased Morphometric Assessment of Red Blood Cell Storage Lesion in the Presence of Shear-Induced Stomatocytes [0.03%]
无偏红细胞形态学评估储存损伤及剪切诱导 stomatocyte 形态异常的作用
Clemens Boecker,Jose Luis Halblaub Miranda,Harald Klüter et al.
Clemens Boecker et al.
Introduction: Red blood cells (RBCs) undergo progressive biochemical and morphological changes during storage, collectively called storage lesion. The quality of red cell concentrates (RCCs) is typically assessed by quant...
A Rare Variant c.1024A>C in the ABO*A1.02 Allele Was Associated with an Ael Phenotype [0.03%]
ABO*A1.02等位基因c.1024A>C罕见变异与Ael表型相关
Yan Li,Mengyuan Ding,Zhaoze Ma et al.
Yan Li et al.
Introduction: Ael is known to be one of the weakest A subgroups and can be identified through either the adsorption-elution technique or molecular analysis. Single nucleotide variation in the ABO gene can potentially disr...
Rainer Moog,Lena Brückle,Oliver Xia
Rainer Moog
Background and objectives: Blood donor release prior to donation by a physician is mandatory in Germany according to current guidelines. Due to shortage of qualified staff, the German Transfusion Act was modified allowing...