High-Throughput Next-Generation Sequencing of the Kidd Blood Group: Unexpected Antigen Expression Properties of Four Alleles and Detection of Novel Variants [0.03%]
Kidd血型系统的高效次代测序：四个等位基因的意外抗原表达性质及新变异的发现
Stephanie M Vorholt,Veronika Lenz,Burkhard Just et al.
Stephanie M Vorholt et al.
Background: The blood supply for patients with foreign ethnic backgrounds can be challenging, as they often have blood group and HPA patterns that differ from the variants prevalent in the German population. In addition, ...
Phenotyping and Genotyping of HNA: Prevalence, Risk of Alloimmunization, and HNA Incompatibilities in Indians [0.03%]
印度人HNA表型和基因型的分布、输血致敏风险及不相容情况的研究
Harita Gogri,Meghana Parihar,Swati Kulkarni et al.
Harita Gogri et al.
Background: Antibodies to human neutrophil alloantigens (HNA) are involved in the pathophysiology of several clinical conditions including transfusion-related acute lung injury (TRALI), alloimmune and autoimmune neutropen...
Risk Factors and Outcomes of Stem Cell Mobilization Failure in Multiple Myeloma Patients [0.03%]
移植前造血干细胞动员失败的多发性骨髓瘤患者的危险因素及转归分析
Te-Lin Hsu,Chun-Kuang Tsai,Chun-Yu Liu et al.
Te-Lin Hsu et al.
Introduction: Autologous hematopoietic stem cell transplantation (ASCT) is a well-established treatment for patients with multiple myeloma (MM), and adequate stem cell collection must be assured before ASCT. However, pred...
Factor XIII in the Acute Care Setting and Its Relevance in Obstetric Bleeding [0.03%]
因子 XIII 在急诊医学中的作用及其在产科出血中的相关性
Patricia Duque,Wolfgang Korte
Patricia Duque
Background: Major hemorrhage is one of the main causes of preventable mortality in either severe trauma, high-risk surgical patient, or the obstetric population. As underlined by the cell-based coagulation model, a resist...
Successful Management of Severe Hyperhaemolysis with Combined Tocilizumab and Rituximab in Non-Transfusion-Dependent Thalassaemia: A Case Report [0.03%]
成功使用托珠单抗和利妥昔单抗联合治疗非输血依赖性地中海贫血重症溶血1例报告
Amal M El Afifi,Alia M Saeed,Gihad H Fekry et al.
Amal M El Afifi et al.
Introduction: This is the fourth case reporting the administration of tocilizumab to control hyperhaemolysis. It was administered with rituximab to stop hyperhaemolysis refractory to frontline therapy. Hyperhaemolysis is ...
Effect of Blood Groups on Clinical Presentations and Treatment Outcomes in Immune Thrombotic Thrombocytopenic Purpura Patients with Severe ADAMTS13 Deficiency: A Multi-Center Experience [0.03%]
ABO血型对严重ADAMTS13缺乏的免疫性血栓性血小板减少性紫癜临床表现和治疗结局的影响：多中心经验
Murat Yıldırım,Selim Sayın,Ahmet Kürşad Güneş et al.
Murat Yıldırım et al.
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy caused by accumulation of ultra-large von Willebrand factor (vWF) due to the significantly reduced activity ADAMTS13. Limited studies...
Follow-Up of Plasma Donors after Quarantine Storage: Results of a 5-Year Survey in Germany [0.03%]
德国检疫储存后的血浆捐献血浆者随访调查结果——5年回顾
Sarah Anna Fiedler,Doris Oberle,Olaf Henseler et al.
Sarah Anna Fiedler et al.
Background and objectives: In 1993, a quarantine storage of 6 months was introduced for plasma for transfusion and was reduced to 4 months in 2003, owing to the improvements of screening assays used in German blood establ...
The Impact of Prepartum Platelet Count on Postpartum Blood Loss and Its Association with Coagulation Factor XIII Activity [0.03%]
孕前血小板计数对产后出血的影响及其与凝血因子XIII活性的关系
Romana Brun,Torsten Hothorn,Eva Eigenmann et al.
Romana Brun et al.
Background: Postpartum hemorrhage is a leading cause of maternal morbidity and mortality worldwide. Contradictory information exists regarding the relevance of prepartum platelet count on postpartum hemorrhage. We have sh...
A Novel Mutation Eliminates GATA-1 and RUNX1-Mediated Promoter Activity in Galactosyltransferase Gene [0.03%]
一个新的突变消除了GATA-1和RUNX1介导的半乳糖基转移酶基因启动子活性
Fengxia Liu,Guocai Li,Jian Li et al.
Fengxia Liu et al.
Introduction: Mutations in the promoter region and exons of ABO gene may cause changes in the expression of blood group antigens, often showing a weak ABO phenotype. Here, we identified a novel weak ABO subgroup allele th...
Occurrence of Rare Deletional Yus and Gerbich Alleles in Syria and Neighbouring Countries [0.03%]
罕见的Yus和Gerbich等位基因缺失在叙利亚及邻国的发生情况
Christoph Gassner,Vanessa Scherer,Daniela Zanolin-Purin et al.
Christoph Gassner et al.
Background: Gerbich-negative phenotypes of the Gerbich Blood Group System (ISBT 020) are very rare (with the exception of Papua New Guinea). The Gerbich-negative phenotypes Yus and Gerbich are negative for the antigens Ge...