Rituximab in the treatment of anti-neutrophil cytoplasm antibody-associated vasculitis [0.03%]
利妥昔单抗治疗抗中性粒细胞胞浆抗体相关性血管炎
Rachel B Jones
Rachel B Jones
The introduction of cyclophosphamide and high-dose glucocorticoids for anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) has allowed a reduction in 1-year mortality from 80% to 10-20%. AAV is now a chronic disease, and g...
Pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis and potential targets for biologic treatment [0.03%]
抗中性粒细胞胞浆自身抗体相关性血管炎的发病机制及生物治疗潜在靶点
J S F Sanders,W H Abdulahad,C A Stegeman et al.
J S F Sanders et al.
Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV) are autoimmune diseases in which the small vessels are inflamed. Clinical observations suggest a pathogenic role for ANCA. Such a role is supported by in vitro exp...
JTT-751 for treatment of patients with hyperphosphatemia on peritoneal dialysis [0.03%]
JTT-751治疗腹膜透析患者高磷血症的疗效及安全性研究
Keitaro Yokoyama,Takashi Akiba,Masafumi Fukagawa et al.
Keitaro Yokoyama et al.
Background/aims: JTT-751 (ferric citrate hydrate) is a novel iron-based phosphate approved in Japan for the treatment of hyperphosphatemia in dialysis and nondialysis patients with chronic kidney disease. ...
Clinical Trial
Nephron. Clinical practice. 2014;128(1-2):135-40. DOI:10.1159/000366482 2014
Efficacy of oral hydration in the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography or intervention [0.03%]
口服水化预防冠状动脉造影或介入手术患者对比剂引起的急性肾损伤的有效性
Sukru Akyuz,Mehmet Karaca,Tugba Kemaloglu Oz et al.
Sukru Akyuz et al.
Background: Efficacy of intravenous (IV) volume expansion in preventing contrast-induced acute kidney injury (CI-AKI) is well known. However, the role of oral hydration has not been well established. The aim of this work ...
Randomized Controlled Trial
Nephron. Clinical practice. 2014;128(1-2):95-100. DOI:10.1159/000365090 2014
Association of serum bicarbonate with bone fractures in hemodialysis patients: the mineral and bone disorder outcomes study for Japanese CKD stage 5D patients (MBD-5D) [0.03%]
血清碳酸氢盐与日本终末期肾病患者骨折的相关性：终末期肾病患者的矿物质及骨骼异常结果研究（MBD-5D）
Akihiko Kato,Ryo Kido,Yoshihiro Onishi et al.
Akihiko Kato et al.
Background/aims: Bone fracture is often complicated in hemodialysis (HD) patients. Metabolic acidosis is related to bone disease and muscle wasting, but it is not known whether acid-base disturbance is associated with the...
Observational Study
Nephron. Clinical practice. 2014;128(1-2):79-87. DOI:10.1159/000365089 2014
Geriatric assessment for therapeutic decision-making regarding renal replacement in elderly patients with advanced chronic kidney disease [0.03%]
老年慢性肾脏病患者透析治疗决策的姑息性评估措施研究
Isabel Rodriguez Villarreal,Olimpia Ortega,Julie Hinostroza et al.
Isabel Rodriguez Villarreal et al.
In patients older than 75 years with advanced chronic kidney disease (CKD), the decision between treatment with dialysis [intention to treat with dialysis (ITD)] or conservative care (CC) is a challenge. Geriatric assessment can be helpful....
Longitudinal assessments of erythropoietin-stimulating agent responsiveness and the association with specific clinical outcomes in dialysis patients [0.03%]
评估透析患者促红细胞生成素疗效的长期评价及其与特定临床结果的关系
Andreas Schneider,Lena Gutjahr-Lengsfeld,Eberhard Ritz et al.
Andreas Schneider et al.
Background: Dose requirements of erythropoietin-stimulating agents (ESAs) can vary considerably over time and may be associated with cardiovascular outcomes. We aimed to longitudinally assess ESA responsiveness over time ...
Clinical and biological determinants of sclerostin plasma concentration in hemodialysis patients [0.03%]
血液透析患者血浆抗硬化素浓度的影响因素
Pierre Delanaye,Jean-Marie Krzesinski,Xavier Warling et al.
Pierre Delanaye et al.
Background: Sclerostin is a potent inhibitor of bone formation, but the meaning of its serum levels remains undetermined. We evaluated the association between sclerostin levels and clinical or biological data in hemodialy...
Observational Study
Nephron. Clinical practice. 2014;128(1-2):127-34. DOI:10.1159/000366449 2014
Treatment with haemodiafiltration stabilises vascular stiffness (measured by aortic pulse wave velocity) compared to haemodialysis [0.03%]
与血液透析相比，血浆滤过吸附治疗可稳定血管顺应性(以主动脉脉搏波速度测量)
Evangelia Charitaki,Daniel Belman,Andrew Davenport
Evangelia Charitaki
Background/aims: Cerebrovascular diseases such as stroke are increased in dialysis patients, and haemodiafiltration has been reported to reduce cerebrovascular mortality compared to haemodialysis. We wished to determine w...
Comparative Study
Nephron. Clinical practice. 2014;128(1-2):185-91. DOI:10.1159/000368242 2014
Platelet-derived growth factor receptor-β expression in human peritoneum [0.03%]
人腹膜血小板源性生长因子受体-β的表达
Harald Seeger,Niko Braun,Joerg Latus et al.
Harald Seeger et al.
Introduction: Simple peritoneal fibrosis and encapsulating peritoneal sclerosis (EPS) are important lesions in the peritoneum of patients on peritoneal dialysis (PD). We have previously described a population of podoplani...